LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4ICL0_LEIIN
TriTrypDb:
LINF_360018200
Length:
773

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4ICL0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICL0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 723 727 PF00656 0.436
CLV_NRD_NRD_1 318 320 PF00675 0.402
CLV_PCSK_KEX2_1 318 320 PF00082 0.402
CLV_PCSK_SKI1_1 145 149 PF00082 0.513
CLV_PCSK_SKI1_1 166 170 PF00082 0.416
CLV_PCSK_SKI1_1 24 28 PF00082 0.551
CLV_PCSK_SKI1_1 268 272 PF00082 0.513
CLV_PCSK_SKI1_1 378 382 PF00082 0.411
CLV_PCSK_SKI1_1 403 407 PF00082 0.513
CLV_PCSK_SKI1_1 451 455 PF00082 0.355
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HYL2 Leptomonas seymouri 43% 100%
A0A3S7XAL8 Leishmania donovani 99% 100%
A4HNY4 Leishmania braziliensis 76% 100%
E9ASP4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q1V2 Leishmania major 93% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS