DUF4164 family protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4ICJ2_LEIIN

TriTrypDb:

LINF_360036400

Length:

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ICJ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICJ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DOC_USP7_UBL2_3	55	59	PF12436	0.672
LIG_BIR_II_1	1	5	PF00653	0.522
LIG_FHA_1	41	47	PF00498	0.548
LIG_FHA_1	71	77	PF00498	0.625
LIG_FHA_2	1	7	PF00498	0.518
MOD_CK1_1	60	66	PF00069	0.606
MOD_CK1_1	70	76	PF00069	0.504
MOD_GlcNHglycan	67	70	PF01048	0.573
MOD_NEK2_1	57	62	PF00069	0.608
MOD_NEK2_1	67	72	PF00069	0.610
MOD_PIKK_1	67	73	PF00454	0.605
MOD_PKA_2	60	66	PF00069	0.698
TRG_ER_diArg_1	14	17	PF00400	0.580

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I666	Leptomonas seymouri	51%	98%
A0A3Q8IG76	Leishmania donovani	100%	100%
A4HPF1	Leishmania braziliensis	87%	100%
D0A3G0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	97%
E9AT62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q1D5	Leishmania major	96%	100%