LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
DnaJ domain containing protein - putative
Species:
Leishmania infantum
UniProt:
A4ICE4_LEIIN
TriTrypDb:
LINF_360059200
Length:
346

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ICE4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICE4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 110 112 PF00675 0.634
CLV_NRD_NRD_1 118 120 PF00675 0.557
CLV_NRD_NRD_1 203 205 PF00675 0.413
CLV_NRD_NRD_1 222 224 PF00675 0.501
CLV_NRD_NRD_1 247 249 PF00675 0.735
CLV_NRD_NRD_1 251 253 PF00675 0.727
CLV_NRD_NRD_1 271 273 PF00675 0.591
CLV_NRD_NRD_1 43 45 PF00675 0.578
CLV_PCSK_FUR_1 116 120 PF00082 0.597
CLV_PCSK_KEX2_1 116 118 PF00082 0.596
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P554 Leptomonas seymouri 66% 92%
A0A1X0P394 Trypanosomatidae 39% 87%
A0A3Q8IRL6 Leishmania donovani 100% 100%
A0A3R7NA51 Trypanosoma rangeli 49% 97%
A4HQ14 Leishmania braziliensis 81% 100%
D0A8V6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 46% 100%
E9ATT1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 99%
Q4Q0R5 Leishmania major 90% 98%
V5BDN3 Trypanosoma cruzi 48% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS