Calphotin-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

calphotin-like protein

Species:

Leishmania infantum

UniProt:

A4ICC7_LEIIN

TriTrypDb:

LINF_360080600

Length:

429

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4ICC7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4ICC7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	245	249	PF00656	0.740
CLV_NRD_NRD_1	282	284	PF00675	0.640
CLV_NRD_NRD_1	299	301	PF00675	0.449
CLV_PCSK_KEX2_1	188	190	PF00082	0.784
CLV_PCSK_KEX2_1	282	284	PF00082	0.644
CLV_PCSK_KEX2_1	298	300	PF00082	0.475
CLV_PCSK_KEX2_1	305	307	PF00082	0.608
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.784
CLV_PCSK_PC1ET2_1	282	284	PF00082	0.629
CLV_PCSK_PC1ET2_1	298	300	PF00082	0.400
CLV_PCSK_PC1ET2_1	305	307	PF00082	0.631
CLV_PCSK_SKI1_1	17	21	PF00082	0.653
CLV_PCSK_SKI1_1	185	189	PF00082	0.617
CLV_PCSK_SKI1_1	221	225	PF00082	0.766
CLV_PCSK_SKI1_1	351	355	PF00082	0.625
DEG_APCC_DBOX_1	410	418	PF00400	0.713
DEG_SCF_FBW7_1	392	399	PF00400	0.599
DOC_CKS1_1	393	398	PF01111	0.601
DOC_MAPK_MEF2A_6	330	338	PF00069	0.582
DOC_PP1_RVXF_1	15	22	PF00149	0.622
DOC_PP1_RVXF_1	199	205	PF00149	0.609
DOC_PP2B_LxvP_1	56	59	PF13499	0.783
DOC_PP4_FxxP_1	270	273	PF00568	0.608
DOC_USP7_MATH_1	384	388	PF00917	0.615
DOC_USP7_MATH_1	397	401	PF00917	0.559
DOC_WW_Pin1_4	117	122	PF00397	0.772
DOC_WW_Pin1_4	269	274	PF00397	0.606
DOC_WW_Pin1_4	3	8	PF00397	0.754
DOC_WW_Pin1_4	31	36	PF00397	0.723
DOC_WW_Pin1_4	317	322	PF00397	0.519
DOC_WW_Pin1_4	392	397	PF00397	0.667
DOC_WW_Pin1_4	409	414	PF00397	0.737
DOC_WW_Pin1_4	63	68	PF00397	0.726
DOC_WW_Pin1_4	9	14	PF00397	0.698
LIG_14-3-3_CanoR_1	143	150	PF00244	0.707
LIG_14-3-3_CanoR_1	178	184	PF00244	0.653
LIG_14-3-3_CanoR_1	189	197	PF00244	0.497
LIG_14-3-3_CanoR_1	228	234	PF00244	0.789
LIG_14-3-3_CanoR_1	73	80	PF00244	0.734
LIG_BIR_II_1	1	5	PF00653	0.798
LIG_EVH1_2	121	125	PF00568	0.782
LIG_FHA_1	18	24	PF00498	0.745
LIG_FHA_1	188	194	PF00498	0.684
LIG_FHA_1	241	247	PF00498	0.710
LIG_FHA_1	26	32	PF00498	0.661
LIG_FHA_1	308	314	PF00498	0.555
LIG_FHA_2	243	249	PF00498	0.738
LIG_FHA_2	73	79	PF00498	0.808
LIG_LIR_Gen_1	160	169	PF02991	0.644
LIG_LIR_Nem_3	160	164	PF02991	0.547
LIG_LIR_Nem_3	291	297	PF02991	0.608
LIG_LIR_Nem_3	344	350	PF02991	0.556
LIG_LYPXL_S_1	108	112	PF13949	0.749
LIG_LYPXL_yS_3	109	112	PF13949	0.749
LIG_MYND_1	39	43	PF01753	0.649
LIG_PCNA_PIPBox_1	208	217	PF02747	0.652
LIG_PDZ_Class_1	424	429	PF00595	0.601
LIG_Pex14_1	265	269	PF04695	0.583
LIG_SH2_CRK	98	102	PF00017	0.668
LIG_SH2_STAT5	161	164	PF00017	0.537
LIG_SH2_STAT5	215	218	PF00017	0.685
LIG_SH2_STAT5	269	272	PF00017	0.605
LIG_SH2_STAT5	294	297	PF00017	0.607
LIG_SH3_3	174	180	PF00018	0.725
LIG_SH3_3	30	36	PF00018	0.603
LIG_SH3_3	362	368	PF00018	0.629
LIG_SH3_3	390	396	PF00018	0.611
LIG_SH3_3	4	10	PF00018	0.733
LIG_SH3_3	40	46	PF00018	0.624
LIG_SH3_3	56	62	PF00018	0.511
LIG_SH3_3	64	70	PF00018	0.624
LIG_SUMO_SIM_anti_2	332	340	PF11976	0.446
LIG_SUMO_SIM_par_1	179	184	PF11976	0.775
LIG_SUMO_SIM_par_1	332	340	PF11976	0.446
LIG_TRAF2_1	74	77	PF00917	0.812
LIG_Vh1_VBS_1	324	342	PF01044	0.520
LIG_WW_1	158	161	PF00397	0.707
MOD_CK1_1	117	123	PF00069	0.668
MOD_CK1_1	170	176	PF00069	0.599
MOD_CK1_1	229	235	PF00069	0.769
MOD_CK1_1	3	9	PF00069	0.742
MOD_CK1_1	317	323	PF00069	0.516
MOD_CK1_1	355	361	PF00069	0.632
MOD_CK2_1	142	148	PF00069	0.560
MOD_CK2_1	275	281	PF00069	0.447
MOD_CK2_1	72	78	PF00069	0.815
MOD_GlcNHglycan	116	119	PF01048	0.624
MOD_GlcNHglycan	137	140	PF01048	0.563
MOD_GlcNHglycan	169	172	PF01048	0.633
MOD_GlcNHglycan	2	5	PF01048	0.517
MOD_GlcNHglycan	23	26	PF01048	0.712
MOD_GlcNHglycan	290	293	PF01048	0.539
MOD_GlcNHglycan	339	342	PF01048	0.554
MOD_GlcNHglycan	354	357	PF01048	0.395
MOD_GSK3_1	113	120	PF00069	0.755
MOD_GSK3_1	17	24	PF00069	0.752
MOD_GSK3_1	227	234	PF00069	0.783
MOD_GSK3_1	240	247	PF00069	0.576
MOD_GSK3_1	392	399	PF00069	0.705
MOD_NEK2_1	113	118	PF00069	0.748
MOD_NEK2_1	181	186	PF00069	0.714
MOD_NEK2_1	21	26	PF00069	0.711
MOD_NEK2_1	337	342	PF00069	0.487
MOD_PK_1	330	336	PF00069	0.456
MOD_PKA_1	17	23	PF00069	0.781
MOD_PKA_1	188	194	PF00069	0.634
MOD_PKA_2	142	148	PF00069	0.708
MOD_PKA_2	167	173	PF00069	0.537
MOD_PKA_2	188	194	PF00069	0.756
MOD_PKA_2	227	233	PF00069	0.736
MOD_PKA_2	342	348	PF00069	0.531
MOD_PKA_2	72	78	PF00069	0.740
MOD_Plk_1	343	349	PF00069	0.464
MOD_Plk_4	275	281	PF00069	0.424
MOD_Plk_4	307	313	PF00069	0.604
MOD_Plk_4	330	336	PF00069	0.525
MOD_Plk_4	361	367	PF00069	0.575
MOD_ProDKin_1	117	123	PF00069	0.773
MOD_ProDKin_1	269	275	PF00069	0.608
MOD_ProDKin_1	3	9	PF00069	0.753
MOD_ProDKin_1	31	37	PF00069	0.726
MOD_ProDKin_1	317	323	PF00069	0.516
MOD_ProDKin_1	392	398	PF00069	0.670
MOD_ProDKin_1	409	415	PF00069	0.738
MOD_ProDKin_1	63	69	PF00069	0.728
MOD_SUMO_for_1	91	94	PF00179	0.613
TRG_DiLeu_BaLyEn_6	67	72	PF01217	0.731
TRG_ENDOCYTIC_2	109	112	PF00928	0.624
TRG_ENDOCYTIC_2	161	164	PF00928	0.569
TRG_ENDOCYTIC_2	215	218	PF00928	0.676
TRG_ENDOCYTIC_2	98	101	PF00928	0.633
TRG_NLS_Bipartite_1	282	302	PF00514	0.472

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGY1	Leishmania donovani	100%	100%
A4HQK7	Leishmania braziliensis	67%	100%
E9AUC2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q068	Leishmania major	86%	100%