LeishMANIAdb
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Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transmembrane protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IC98_LEIIN
TriTrypDb:
LINF_360075600
Length:
206

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 4
GO:0110165 cellular anatomical entity 1 4
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Expansion

Sequence features

A4IC98
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IC98

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 162 164 PF00675 0.516
CLV_PCSK_KEX2_1 162 164 PF00082 0.516
CLV_PCSK_SKI1_1 71 75 PF00082 0.296
DEG_APCC_DBOX_1 6 14 PF00400 0.385
DEG_Nend_Nbox_1 1 3 PF02207 0.351
DEG_SPOP_SBC_1 149 153 PF00917 0.582
DOC_MAPK_FxFP_2 56 59 PF00069 0.318
DOC_MAPK_MEF2A_6 7 15 PF00069 0.385
DOC_MAPK_MEF2A_6 71 78 PF00069 0.374
DOC_MAPK_NFAT4_5 71 79 PF00069 0.325
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P600 Leptomonas seymouri 64% 74%
A0A1X0NN71 Trypanosomatidae 35% 79%
A0A3Q8IK72 Leishmania donovani 100% 100%
A4HQG2 Leishmania braziliensis 74% 100%
E9AU78 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4Q0B6 Leishmania major 94% 100%
V5B8C5 Trypanosoma cruzi 36% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS