LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Domain of unknown function (DUF4496) - putative
Species:
Leishmania infantum
UniProt:
A4IC97_LEIIN
TriTrypDb:
LINF_360075500
Length:
532

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005815 microtubule organizing center 2 1
GO:0036064 ciliary basal body 3 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4IC97
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IC97

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 239 243 PF00656 0.798
CLV_C14_Caspase3-7 487 491 PF00656 0.613
CLV_NRD_NRD_1 187 189 PF00675 0.524
CLV_NRD_NRD_1 272 274 PF00675 0.592
CLV_NRD_NRD_1 286 288 PF00675 0.587
CLV_NRD_NRD_1 294 296 PF00675 0.566
CLV_NRD_NRD_1 329 331 PF00675 0.795
CLV_NRD_NRD_1 416 418 PF00675 0.721
CLV_NRD_NRD_1 438 440 PF00675 0.679
CLV_NRD_NRD_1 46 48 PF00675 0.455
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I476 Leptomonas seymouri 56% 94%
A0A3Q8IPX9 Leishmania donovani 99% 100%
A4HQG1 Leishmania braziliensis 76% 100%
E9AU77 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q0B7 Leishmania major 92% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS