Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

GTPase activating protein - putative

Species:

Leishmania infantum

UniProt:

A4IC93_LEIIN

TriTrypDb:

LINF_360075000

Length:

557

Annotations

Annotations by Jardim et al.

Intracellular protein trafficking, GTPase activating Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Previous1Next

Expansion

Sequence features

A4IC93

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IC93

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0015931	nucleobase-containing compound transport	5	1
GO:0050657	nucleic acid transport	6	1
GO:0050658	RNA transport	4	1
GO:0051028	mRNA transport	5	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0051236	establishment of RNA localization	3	1
GO:0071702	organic substance transport	4	1
GO:0071705	nitrogen compound transport	4	1

Previous1Next

Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	420	424	PF00656	0.357
CLV_C14_Caspase3-7	490	494	PF00656	0.383
CLV_NRD_NRD_1	274	276	PF00675	0.463
CLV_NRD_NRD_1	308	310	PF00675	0.341
CLV_NRD_NRD_1	68	70	PF00675	0.467
CLV_PCSK_KEX2_1	308	310	PF00082	0.374
CLV_PCSK_KEX2_1	505	507	PF00082	0.526
CLV_PCSK_KEX2_1	529	531	PF00082	0.480
CLV_PCSK_PC1ET2_1	505	507	PF00082	0.526
CLV_PCSK_PC1ET2_1	529	531	PF00082	0.472

Previous1 2 3 4 5…17Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL31	Leptomonas seymouri	65%	90%
A0A0S4IUJ5	Bodo saltans	51%	98%
A0A1X0NLM8	Trypanosomatidae	54%	100%
A0A3Q8IRX0	Leishmania donovani	99%	100%
A0A3R7LIA2	Trypanosoma rangeli	53%	100%
A4HQF7	Leishmania braziliensis	78%	100%
D0A3K6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
E9AU73	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4Q0C1	Leishmania major	96%	100%
V5B8C0	Trypanosoma cruzi	55%	98%

Previous1Next