LeishMANIAdb
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ABC transmembrane type-1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ABC transmembrane type-1 domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IC72_LEIIN
TriTrypDb:
LINF_350055100 *
Length:
169

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 4
GO:0110165 cellular anatomical entity 1 4
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Expansion

Sequence features

A4IC72
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IC72

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 105 107 PF00675 0.547
CLV_NRD_NRD_1 147 149 PF00675 0.463
CLV_NRD_NRD_1 80 82 PF00675 0.722
CLV_NRD_NRD_1 85 87 PF00675 0.676
CLV_PCSK_KEX2_1 101 103 PF00082 0.796
CLV_PCSK_KEX2_1 136 138 PF00082 0.517
CLV_PCSK_PC1ET2_1 101 103 PF00082 0.738
CLV_PCSK_PC1ET2_1 136 138 PF00082 0.517
CLV_PCSK_PC7_1 97 103 PF00082 0.790
CLV_PCSK_SKI1_1 148 152 PF00082 0.442
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IVL9 Leishmania donovani 99% 81%
A4HNF9 Leishmania braziliensis 78% 100%
E9AFX0 Leishmania major 92% 100%
E9B723 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS