BZIP domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IC26_LEIIN

TriTrypDb:

LINF_350054600

Length:

153

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IC26

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IC26

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0016740	transferase activity	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	52	56	PF00656	0.697
CLV_NRD_NRD_1	39	41	PF00675	0.682
CLV_NRD_NRD_1	44	46	PF00675	0.697
CLV_PCSK_FUR_1	37	41	PF00082	0.551
CLV_PCSK_KEX2_1	39	41	PF00082	0.611
CLV_PCSK_PC7_1	35	41	PF00082	0.593
CLV_PCSK_SKI1_1	149	153	PF00082	0.647
DEG_SPOP_SBC_1	72	76	PF00917	0.765
DOC_PP2B_LxvP_1	62	65	PF13499	0.546
LIG_14-3-3_CanoR_1	3	11	PF00244	0.636
LIG_14-3-3_CterR_2	149	153	PF00244	0.558
LIG_BIR_III_4	55	59	PF00653	0.698
LIG_Clathr_ClatBox_1	120	124	PF01394	0.454
LIG_deltaCOP1_diTrp_1	143	148	PF00928	0.650
LIG_deltaCOP1_diTrp_1	98	107	PF00928	0.548
LIG_FHA_2	120	126	PF00498	0.368
LIG_FHA_2	50	56	PF00498	0.691
LIG_LIR_Gen_1	98	107	PF02991	0.482
LIG_LIR_Nem_3	130	136	PF02991	0.540
LIG_LIR_Nem_3	143	147	PF02991	0.474
LIG_LIR_Nem_3	98	103	PF02991	0.491
LIG_PDZ_Class_2	148	153	PF00595	0.462
LIG_Pex14_1	144	148	PF04695	0.488
LIG_SH2_STAT5	119	122	PF00017	0.520
LIG_SH2_STAT5	147	150	PF00017	0.638
LIG_SH3_3	89	95	PF00018	0.490
LIG_SUMO_SIM_anti_2	113	118	PF11976	0.474
LIG_SUMO_SIM_par_1	118	126	PF11976	0.403
LIG_TRAF2_1	122	125	PF00917	0.490
MOD_CK2_1	119	125	PF00069	0.368
MOD_GlcNHglycan	41	44	PF01048	0.557
MOD_GlcNHglycan	51	55	PF01048	0.678
MOD_GlcNHglycan	75	78	PF01048	0.606
MOD_GSK3_1	50	57	PF00069	0.641
MOD_PK_1	7	13	PF00069	0.483
MOD_PKA_1	39	45	PF00069	0.574
MOD_PKA_2	2	8	PF00069	0.655
MOD_PKA_2	39	45	PF00069	0.563
MOD_PKB_1	37	45	PF00069	0.564
TRG_ER_diArg_1	33	36	PF00400	0.641
TRG_ER_diArg_1	39	41	PF00400	0.583

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I444	Leptomonas seymouri	55%	98%
A0A1X0P5P2	Trypanosomatidae	29%	100%
A0A3S5H809	Leishmania donovani	100%	100%
A4HNF4	Leishmania braziliensis	74%	100%
E9AFW5	Leishmania major	91%	100%
E9B718	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%