LeishMANIAdb
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PHM7_ext domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
PHM7_ext domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IC20_LEIIN
TriTrypDb:
LINF_350054000
Length:
256

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) yes yes: 2
Forrest at al. (procyclic) yes yes: 2
Silverman et al. no yes: 0
Pissara et al. no yes: 6
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 3
GO:0110165 cellular anatomical entity 1 3
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Expansion

Sequence features

A4IC20
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IC20

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 254 256 PF00675 0.823
CLV_PCSK_SKI1_1 83 87 PF00082 0.466
DEG_APCC_DBOX_1 82 90 PF00400 0.658
DEG_Nend_Nbox_1 1 3 PF02207 0.527
DOC_CKS1_1 7 12 PF01111 0.505
DOC_CYCLIN_yCln2_LP_2 43 49 PF00134 0.459
DOC_CYCLIN_yCln2_LP_2 85 91 PF00134 0.664
DOC_PP2B_LxvP_1 85 88 PF13499 0.692
DOC_PP4_FxxP_1 221 224 PF00568 0.474
DOC_PP4_FxxP_1 228 231 PF00568 0.449
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IJX6 Leishmania donovani 99% 100%
E9AFV9 Leishmania major 91% 100%
E9B712 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 73%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS