Uncharacterized protein

Quick info Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

predicted zinc finger protein

Species:

Leishmania infantum

UniProt:

A4IBY5_LEIIN

TriTrypDb:

LINF_350050300

Length:

264

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 128

Expansion

Sequence features

A4IBY5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBY5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	6
GO:0043167	ion binding	2	6
GO:0043169	cation binding	3	6
GO:0046872	metal ion binding	4	6
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	196	198	PF00675	0.599
CLV_PCSK_KEX2_1	196	198	PF00082	0.599
DEG_Nend_Nbox_1	1	3	PF02207	0.666
DEG_SCF_FBW7_1	236	242	PF00400	0.692
DOC_CKS1_1	150	155	PF01111	0.547
DOC_CKS1_1	160	165	PF01111	0.524
DOC_CKS1_1	236	241	PF01111	0.660
DOC_CKS1_1	5	10	PF01111	0.653
DOC_CKS1_1	55	60	PF01111	0.558
DOC_CYCLIN_yCln2_LP_2	206	212	PF00134	0.581
DOC_PP1_RVXF_1	123	130	PF00149	0.511
DOC_PP4_FxxP_1	201	204	PF00568	0.554
DOC_PP4_FxxP_1	251	254	PF00568	0.678
DOC_USP7_MATH_1	219	223	PF00917	0.600
DOC_USP7_MATH_1	239	243	PF00917	0.538
DOC_WW_Pin1_4	109	114	PF00397	0.647
DOC_WW_Pin1_4	140	145	PF00397	0.692
DOC_WW_Pin1_4	149	154	PF00397	0.606
DOC_WW_Pin1_4	159	164	PF00397	0.467
DOC_WW_Pin1_4	205	210	PF00397	0.671
DOC_WW_Pin1_4	215	220	PF00397	0.573
DOC_WW_Pin1_4	232	237	PF00397	0.544
DOC_WW_Pin1_4	4	9	PF00397	0.690
DOC_WW_Pin1_4	54	59	PF00397	0.627
DOC_WW_Pin1_4	78	83	PF00397	0.635
LIG_14-3-3_CanoR_1	125	130	PF00244	0.527
LIG_BRCT_BRCA1_1	125	129	PF00533	0.614
LIG_FHA_1	243	249	PF00498	0.697
LIG_FHA_1	95	101	PF00498	0.671
LIG_FHA_2	216	222	PF00498	0.632
LIG_FHA_2	255	261	PF00498	0.670
LIG_Integrin_isoDGR_2	191	193	PF01839	0.569
LIG_LIR_Apic_2	250	254	PF02991	0.675
LIG_LIR_Gen_1	152	163	PF02991	0.639
LIG_LIR_Gen_1	230	239	PF02991	0.624
LIG_LIR_Gen_1	256	263	PF02991	0.519
LIG_LIR_Nem_3	152	158	PF02991	0.640
LIG_LIR_Nem_3	230	234	PF02991	0.662
LIG_LIR_Nem_3	238	243	PF02991	0.610
LIG_LIR_Nem_3	256	262	PF02991	0.443
LIG_LIR_Nem_3	81	86	PF02991	0.631
LIG_PTB_Apo_2	225	232	PF02174	0.590
LIG_SH2_CRK	155	159	PF00017	0.632
LIG_SH2_CRK	2	6	PF00017	0.613
LIG_SH2_CRK	240	244	PF00017	0.621
LIG_SH2_GRB2like	189	192	PF00017	0.559
LIG_SH2_SRC	189	192	PF00017	0.559
LIG_SH2_SRC	19	22	PF00017	0.656
LIG_SH2_SRC	86	89	PF00017	0.628
LIG_SH2_STAT3	84	87	PF00017	0.632
LIG_SH2_STAT5	189	192	PF00017	0.559
LIG_SH2_STAT5	19	22	PF00017	0.722
LIG_SH3_3	110	116	PF00018	0.617
LIG_SH3_3	147	153	PF00018	0.566
LIG_SH3_3	15	21	PF00018	0.575
LIG_SH3_3	2	8	PF00018	0.699
LIG_SH3_3	206	212	PF00018	0.609
LIG_SH3_3	233	239	PF00018	0.663
LIG_SH3_3	33	39	PF00018	0.468
LIG_SH3_3	52	58	PF00018	0.530
LIG_SH3_3	67	73	PF00018	0.649
LIG_WRC_WIRS_1	248	253	PF05994	0.629
MOD_CK1_1	121	127	PF00069	0.763
MOD_CK1_1	213	219	PF00069	0.624
MOD_CK1_1	235	241	PF00069	0.657
MOD_CK1_1	242	248	PF00069	0.569
MOD_CK1_1	75	81	PF00069	0.719
MOD_CK1_1	94	100	PF00069	0.514
MOD_CK2_1	254	260	PF00069	0.667
MOD_GlcNHglycan	168	171	PF01048	0.724
MOD_GlcNHglycan	221	224	PF01048	0.596
MOD_GSK3_1	105	112	PF00069	0.559
MOD_GSK3_1	121	128	PF00069	0.555
MOD_GSK3_1	215	222	PF00069	0.631
MOD_GSK3_1	235	242	PF00069	0.543
MOD_GSK3_1	249	256	PF00069	0.510
MOD_GSK3_1	90	97	PF00069	0.550
MOD_N-GLC_1	109	114	PF02516	0.547
MOD_N-GLC_1	180	185	PF02516	0.477
MOD_N-GLC_1	95	100	PF02516	0.506
MOD_NEK2_1	118	123	PF00069	0.708
MOD_NEK2_1	166	171	PF00069	0.640
MOD_PIKK_1	134	140	PF00454	0.751
MOD_PIKK_1	164	170	PF00454	0.636
MOD_PIKK_1	20	26	PF00454	0.698
MOD_PIKK_1	254	260	PF00454	0.567
MOD_Plk_1	91	97	PF00069	0.534
MOD_Plk_4	13	19	PF00069	0.674
MOD_Plk_4	258	264	PF00069	0.602
MOD_Plk_4	48	54	PF00069	0.715
MOD_ProDKin_1	109	115	PF00069	0.645
MOD_ProDKin_1	140	146	PF00069	0.690
MOD_ProDKin_1	149	155	PF00069	0.604
MOD_ProDKin_1	159	165	PF00069	0.468
MOD_ProDKin_1	205	211	PF00069	0.673
MOD_ProDKin_1	215	221	PF00069	0.573
MOD_ProDKin_1	232	238	PF00069	0.541
MOD_ProDKin_1	4	10	PF00069	0.691
MOD_ProDKin_1	54	60	PF00069	0.629
MOD_ProDKin_1	78	84	PF00069	0.636
TRG_ENDOCYTIC_2	155	158	PF00928	0.634
TRG_ENDOCYTIC_2	2	5	PF00928	0.618
TRG_ENDOCYTIC_2	240	243	PF00928	0.689
TRG_NLS_MonoExtN_4	196	201	PF00514	0.577
TRG_Pf-PMV_PEXEL_1	200	205	PF00026	0.540

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X9W1	Leishmania donovani	100%	100%
A4HNB3	Leishmania braziliensis	64%	100%
E9AFS2	Leishmania major	89%	100%
E9B6X4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%