LeishMANIAdb
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Si:ch211-242b18.1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Si:ch211-242b18.1
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IBY4_LEIIN
TriTrypDb:
LINF_350050200 *
Length:
95

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBY4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBY4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 87 91 PF00656 0.707
CLV_NRD_NRD_1 59 61 PF00675 0.671
CLV_PCSK_KEX2_1 59 61 PF00082 0.671
DEG_APCC_DBOX_1 59 67 PF00400 0.667
DEG_APCC_DBOX_1 78 86 PF00400 0.344
DOC_ANK_TNKS_1 23 30 PF00023 0.662
DOC_PP4_FxxP_1 35 38 PF00568 0.733
DOC_WW_Pin1_4 30 35 PF00397 0.776
LIG_AP2alpha_1 88 92 PF02296 0.618
LIG_APCC_ABBA_1 32 37 PF00400 0.749
LIG_BIR_II_1 1 5 PF00653 0.552
LIG_BRCT_BRCA1_1 88 92 PF00533 0.521
LIG_FHA_1 4 10 PF00498 0.631
LIG_FHA_1 50 56 PF00498 0.562
LIG_LIR_Apic_2 33 38 PF02991 0.742
LIG_Pex14_2 88 92 PF04695 0.618
LIG_WRC_WIRS_1 85 90 PF05994 0.693
MOD_CK1_1 49 55 PF00069 0.664
MOD_CK1_1 84 90 PF00069 0.560
MOD_GSK3_1 84 91 PF00069 0.690
MOD_NEK2_1 72 77 PF00069 0.544
MOD_NEK2_1 88 93 PF00069 0.446
MOD_PKA_2 3 9 PF00069 0.632
MOD_PKB_1 8 16 PF00069 0.719
MOD_Plk_1 49 55 PF00069 0.564
MOD_ProDKin_1 30 36 PF00069 0.768
MOD_SUMO_for_1 38 41 PF00179 0.707
MOD_SUMO_rev_2 33 40 PF00179 0.734
TRG_DiLeu_BaEn_2 49 55 PF01217 0.664
TRG_ER_diArg_1 58 60 PF00400 0.662
TRG_NES_CRM1_1 46 57 PF08389 0.566

Homologs

Protein Taxonomy Sequence identity Coverage
E9AFS1 Leishmania major 89% 100%
E9B6X3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS