LeishMANIAdb
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N6_Mtase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
N6_Mtase domain-containing protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania infantum
UniProt:
A4IBW0_LEIIN
TriTrypDb:
Length:
486

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBW0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBW0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 275 279 PF00656 0.796
CLV_NRD_NRD_1 119 121 PF00675 0.552
CLV_NRD_NRD_1 85 87 PF00675 0.759
CLV_PCSK_KEX2_1 118 120 PF00082 0.551
CLV_PCSK_KEX2_1 336 338 PF00082 0.575
CLV_PCSK_KEX2_1 85 87 PF00082 0.759
CLV_PCSK_PC1ET2_1 118 120 PF00082 0.477
CLV_PCSK_PC1ET2_1 336 338 PF00082 0.575
CLV_PCSK_SKI1_1 119 123 PF00082 0.669
CLV_PCSK_SKI1_1 12 16 PF00082 0.352
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Homologs

ProteinTaxonomySequence identityCoverage
E9AFP7 Leishmania major 79% 73%
E9B6V0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 76% 68%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS