Uncharacterized protein

Quick info Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IBV2_LEIIN

TriTrypDb:

LINF_350047000

Length:

585

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 419

Expansion

Sequence features

A4IBV2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBV2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	152	156	PF00656	0.707
CLV_C14_Caspase3-7	518	522	PF00656	0.700
CLV_NRD_NRD_1	172	174	PF00675	0.711
CLV_NRD_NRD_1	204	206	PF00675	0.814
CLV_NRD_NRD_1	240	242	PF00675	0.822
CLV_NRD_NRD_1	273	275	PF00675	0.655
CLV_NRD_NRD_1	429	431	PF00675	0.718
CLV_NRD_NRD_1	433	435	PF00675	0.712
CLV_NRD_NRD_1	66	68	PF00675	0.735
CLV_PCSK_KEX2_1	172	174	PF00082	0.711
CLV_PCSK_KEX2_1	204	206	PF00082	0.814
CLV_PCSK_KEX2_1	240	242	PF00082	0.822
CLV_PCSK_KEX2_1	273	275	PF00082	0.661
CLV_PCSK_KEX2_1	290	292	PF00082	0.646
CLV_PCSK_KEX2_1	487	489	PF00082	0.721
CLV_PCSK_KEX2_1	66	68	PF00082	0.735
CLV_PCSK_PC1ET2_1	290	292	PF00082	0.702
CLV_PCSK_PC1ET2_1	487	489	PF00082	0.702
CLV_PCSK_SKI1_1	193	197	PF00082	0.643
CLV_PCSK_SKI1_1	205	209	PF00082	0.708
CLV_PCSK_SKI1_1	340	344	PF00082	0.691
CLV_PCSK_SKI1_1	430	434	PF00082	0.671
DEG_SCF_FBW7_2	43	50	PF00400	0.753
DEG_SPOP_SBC_1	104	108	PF00917	0.740
DEG_SPOP_SBC_1	299	303	PF00917	0.656
DOC_CKS1_1	139	144	PF01111	0.774
DOC_CKS1_1	197	202	PF01111	0.725
DOC_PP2B_LxvP_1	330	333	PF13499	0.742
DOC_PP4_FxxP_1	524	527	PF00568	0.670
DOC_USP7_MATH_1	180	184	PF00917	0.705
DOC_USP7_MATH_1	214	218	PF00917	0.661
DOC_USP7_MATH_1	248	252	PF00917	0.793
DOC_USP7_MATH_1	28	32	PF00917	0.721
DOC_USP7_MATH_1	333	337	PF00917	0.630
DOC_USP7_MATH_1	424	428	PF00917	0.711
DOC_USP7_MATH_1	492	496	PF00917	0.667
DOC_USP7_MATH_1	501	505	PF00917	0.684
DOC_USP7_MATH_1	509	513	PF00917	0.560
DOC_USP7_MATH_1	60	64	PF00917	0.763
DOC_USP7_UBL2_3	431	435	PF12436	0.810
DOC_WW_Pin1_4	138	143	PF00397	0.748
DOC_WW_Pin1_4	196	201	PF00397	0.730
DOC_WW_Pin1_4	224	229	PF00397	0.687
DOC_WW_Pin1_4	235	240	PF00397	0.690
DOC_WW_Pin1_4	301	306	PF00397	0.800
DOC_WW_Pin1_4	322	327	PF00397	0.748
DOC_WW_Pin1_4	347	352	PF00397	0.734
DOC_WW_Pin1_4	41	46	PF00397	0.753
DOC_WW_Pin1_4	481	486	PF00397	0.609
DOC_WW_Pin1_4	523	528	PF00397	0.620
DOC_WW_Pin1_4	533	538	PF00397	0.625
DOC_WW_Pin1_4	56	61	PF00397	0.566
DOC_WW_Pin1_4	564	569	PF00397	0.659
LIG_14-3-3_CanoR_1	12	17	PF00244	0.711
LIG_14-3-3_CanoR_1	193	198	PF00244	0.663
LIG_14-3-3_CanoR_1	204	214	PF00244	0.808
LIG_14-3-3_CanoR_1	247	253	PF00244	0.755
LIG_14-3-3_CanoR_1	256	261	PF00244	0.647
LIG_14-3-3_CanoR_1	278	288	PF00244	0.746
LIG_14-3-3_CanoR_1	37	45	PF00244	0.733
LIG_14-3-3_CanoR_1	488	494	PF00244	0.794
LIG_14-3-3_CanoR_1	54	60	PF00244	0.716
LIG_14-3-3_CanoR_1	561	567	PF00244	0.690
LIG_14-3-3_CanoR_1	580	584	PF00244	0.758
LIG_14-3-3_CanoR_1	79	85	PF00244	0.686
LIG_Actin_WH2_2	190	206	PF00022	0.630
LIG_BIR_II_1	1	5	PF00653	0.814
LIG_EVH1_2	449	453	PF00568	0.749
LIG_FHA_1	105	111	PF00498	0.741
LIG_FHA_1	118	124	PF00498	0.537
LIG_FHA_1	337	343	PF00498	0.791
LIG_FHA_1	431	437	PF00498	0.769
LIG_FHA_1	572	578	PF00498	0.696
LIG_FHA_2	568	574	PF00498	0.679
LIG_LIR_Apic_2	521	527	PF02991	0.670
LIG_LIR_Gen_1	127	138	PF02991	0.586
LIG_LIR_Gen_1	192	202	PF02991	0.639
LIG_LIR_Gen_1	311	319	PF02991	0.704
LIG_LIR_Gen_1	46	56	PF02991	0.776
LIG_LIR_Gen_1	570	577	PF02991	0.672
LIG_LIR_Nem_3	127	133	PF02991	0.627
LIG_LIR_Nem_3	311	316	PF02991	0.772
LIG_LIR_Nem_3	46	51	PF02991	0.777
LIG_LIR_Nem_3	570	575	PF02991	0.705
LIG_PDZ_Class_2	580	585	PF00595	0.763
LIG_Pex14_2	524	528	PF04695	0.670
LIG_PTAP_UEV_1	306	311	PF05743	0.697
LIG_SH2_CRK	313	317	PF00017	0.709
LIG_SH2_NCK_1	249	253	PF00017	0.813
LIG_SH2_NCK_1	313	317	PF00017	0.709
LIG_SH2_STAP1	313	317	PF00017	0.709
LIG_SH3_2	236	241	PF14604	0.718
LIG_SH3_2	482	487	PF14604	0.680
LIG_SH3_3	111	117	PF00018	0.789
LIG_SH3_3	174	180	PF00018	0.726
LIG_SH3_3	233	239	PF00018	0.702
LIG_SH3_3	269	275	PF00018	0.814
LIG_SH3_3	304	310	PF00018	0.685
LIG_SH3_3	446	452	PF00018	0.661
LIG_SH3_3	476	482	PF00018	0.619
LIG_SH3_3	547	553	PF00018	0.704
LIG_SUMO_SIM_par_1	441	446	PF11976	0.586
LIG_SUMO_SIM_par_1	573	578	PF11976	0.694
LIG_WRC_WIRS_1	463	468	PF05994	0.665
MOD_CDC14_SPxK_1	238	241	PF00782	0.819
MOD_CDC14_SPxK_1	484	487	PF00782	0.681
MOD_CDK_SPK_2	235	240	PF00069	0.818
MOD_CDK_SPK_2	347	352	PF00069	0.828
MOD_CDK_SPK_2	564	569	PF00069	0.687
MOD_CDK_SPxK_1	235	241	PF00069	0.819
MOD_CDK_SPxK_1	481	487	PF00069	0.678
MOD_CDK_SPxxK_3	481	488	PF00069	0.679
MOD_CDK_SPxxK_3	523	530	PF00069	0.709
MOD_CK1_1	102	108	PF00069	0.713
MOD_CK1_1	124	130	PF00069	0.795
MOD_CK1_1	149	155	PF00069	0.709
MOD_CK1_1	15	21	PF00069	0.652
MOD_CK1_1	156	162	PF00069	0.628
MOD_CK1_1	183	189	PF00069	0.689
MOD_CK1_1	255	261	PF00069	0.636
MOD_CK1_1	294	300	PF00069	0.659
MOD_CK1_1	301	307	PF00069	0.663
MOD_CK1_1	31	37	PF00069	0.591
MOD_CK1_1	336	342	PF00069	0.736
MOD_CK1_1	346	352	PF00069	0.614
MOD_CK1_1	465	471	PF00069	0.646
MOD_CK1_1	473	479	PF00069	0.656
MOD_CK1_1	535	541	PF00069	0.733
MOD_CK1_1	567	573	PF00069	0.679
MOD_CK1_1	62	68	PF00069	0.691
MOD_CK2_1	226	232	PF00069	0.713
MOD_GlcNHglycan	1	4	PF01048	0.678
MOD_GlcNHglycan	125	129	PF01048	0.704
MOD_GlcNHglycan	134	137	PF01048	0.791
MOD_GlcNHglycan	149	152	PF01048	0.608
MOD_GlcNHglycan	168	171	PF01048	0.652
MOD_GlcNHglycan	216	219	PF01048	0.686
MOD_GlcNHglycan	244	247	PF01048	0.783
MOD_GlcNHglycan	250	253	PF01048	0.652
MOD_GlcNHglycan	293	296	PF01048	0.653
MOD_GlcNHglycan	352	355	PF01048	0.758
MOD_GlcNHglycan	380	383	PF01048	0.797
MOD_GlcNHglycan	393	396	PF01048	0.707
MOD_GlcNHglycan	418	421	PF01048	0.717
MOD_GlcNHglycan	472	475	PF01048	0.762
MOD_GlcNHglycan	494	497	PF01048	0.652
MOD_GlcNHglycan	503	506	PF01048	0.661
MOD_GlcNHglycan	577	580	PF01048	0.658
MOD_GlcNHglycan	93	96	PF01048	0.699
MOD_GSK3_1	117	124	PF00069	0.709
MOD_GSK3_1	12	19	PF00069	0.706
MOD_GSK3_1	149	156	PF00069	0.696
MOD_GSK3_1	157	164	PF00069	0.627
MOD_GSK3_1	180	187	PF00069	0.696
MOD_GSK3_1	189	196	PF00069	0.611
MOD_GSK3_1	214	221	PF00069	0.614
MOD_GSK3_1	222	229	PF00069	0.602
MOD_GSK3_1	248	255	PF00069	0.707
MOD_GSK3_1	290	297	PF00069	0.707
MOD_GSK3_1	299	306	PF00069	0.720
MOD_GSK3_1	31	38	PF00069	0.753
MOD_GSK3_1	342	349	PF00069	0.747
MOD_GSK3_1	389	396	PF00069	0.791
MOD_GSK3_1	397	404	PF00069	0.669
MOD_GSK3_1	426	433	PF00069	0.739
MOD_GSK3_1	488	495	PF00069	0.661
MOD_GSK3_1	544	551	PF00069	0.641
MOD_GSK3_1	55	62	PF00069	0.694
MOD_GSK3_1	560	567	PF00069	0.675
MOD_GSK3_1	571	578	PF00069	0.685
MOD_GSK3_1	98	105	PF00069	0.694
MOD_LATS_1	414	420	PF00433	0.606
MOD_N-GLC_1	147	152	PF02516	0.819
MOD_N-GLC_1	16	21	PF02516	0.717
MOD_N-GLC_1	389	394	PF02516	0.728
MOD_NEK2_1	146	151	PF00069	0.742
MOD_NEK2_1	203	208	PF00069	0.754
MOD_NEK2_1	279	284	PF00069	0.729
MOD_NEK2_1	342	347	PF00069	0.723
MOD_NEK2_1	393	398	PF00069	0.693
MOD_NEK2_1	453	458	PF00069	0.688
MOD_NEK2_1	575	580	PF00069	0.663
MOD_PIKK_1	16	22	PF00454	0.697
MOD_PIKK_1	180	186	PF00454	0.700
MOD_PIKK_1	218	224	PF00454	0.809
MOD_PIKK_1	366	372	PF00454	0.697
MOD_PIKK_1	73	79	PF00454	0.742
MOD_PK_1	12	18	PF00069	0.684
MOD_PK_1	256	262	PF00069	0.697
MOD_PK_1	515	521	PF00069	0.678
MOD_PKA_1	290	296	PF00069	0.671
MOD_PKA_1	430	436	PF00069	0.808
MOD_PKA_1	487	493	PF00069	0.692
MOD_PKA_2	161	167	PF00069	0.765
MOD_PKA_2	180	186	PF00069	0.700
MOD_PKA_2	203	209	PF00069	0.768
MOD_PKA_2	255	261	PF00069	0.674
MOD_PKA_2	290	296	PF00069	0.702
MOD_PKA_2	31	37	PF00069	0.748
MOD_PKA_2	38	44	PF00069	0.708
MOD_PKA_2	400	406	PF00069	0.747
MOD_PKA_2	487	493	PF00069	0.796
MOD_PKA_2	509	515	PF00069	0.699
MOD_PKA_2	560	566	PF00069	0.695
MOD_PKA_2	579	585	PF00069	0.658
MOD_PKA_2	65	71	PF00069	0.798
MOD_Plk_1	389	395	PF00069	0.727
MOD_Plk_4	80	86	PF00069	0.667
MOD_ProDKin_1	138	144	PF00069	0.751
MOD_ProDKin_1	196	202	PF00069	0.726
MOD_ProDKin_1	224	230	PF00069	0.686
MOD_ProDKin_1	235	241	PF00069	0.691
MOD_ProDKin_1	301	307	PF00069	0.798
MOD_ProDKin_1	322	328	PF00069	0.750
MOD_ProDKin_1	347	353	PF00069	0.732
MOD_ProDKin_1	41	47	PF00069	0.752
MOD_ProDKin_1	481	487	PF00069	0.613
MOD_ProDKin_1	523	529	PF00069	0.620
MOD_ProDKin_1	533	539	PF00069	0.629
MOD_ProDKin_1	56	62	PF00069	0.565
MOD_ProDKin_1	564	570	PF00069	0.657
TRG_DiLeu_BaLyEn_6	114	119	PF01217	0.698
TRG_DiLeu_BaLyEn_6	338	343	PF01217	0.691
TRG_DiLeu_BaLyEn_6	459	464	PF01217	0.558
TRG_ENDOCYTIC_2	130	133	PF00928	0.693
TRG_ENDOCYTIC_2	313	316	PF00928	0.713
TRG_ER_diArg_1	11	14	PF00400	0.686
TRG_ER_diArg_1	172	175	PF00400	0.691
TRG_ER_diArg_1	203	205	PF00400	0.809
TRG_ER_diArg_1	239	241	PF00400	0.806
TRG_ER_diArg_1	272	274	PF00400	0.606
TRG_ER_diArg_1	360	363	PF00400	0.772
TRG_Pf-PMV_PEXEL_1	434	439	PF00026	0.679

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3V4	Leptomonas seymouri	37%	100%
A0A3S7X9W4	Leishmania donovani	100%	100%
A4HN84	Leishmania braziliensis	64%	100%
E9AFN9	Leishmania major	88%	100%
E9B6U2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%