LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Chromosome passenger complex (CPC) protein INCENP N terminal - putative
Species:
Leishmania infantum
UniProt:
A4IBT2_LEIIN
TriTrypDb:
LINF_350044900
Length:
604

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005739 mitochondrion 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4IBT2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBT2

PDB structure(s): 7ane_o

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 528 532 PF00656 0.409
CLV_NRD_NRD_1 129 131 PF00675 0.516
CLV_NRD_NRD_1 20 22 PF00675 0.443
CLV_NRD_NRD_1 201 203 PF00675 0.386
CLV_NRD_NRD_1 235 237 PF00675 0.435
CLV_NRD_NRD_1 3 5 PF00675 0.473
CLV_NRD_NRD_1 300 302 PF00675 0.311
CLV_NRD_NRD_1 338 340 PF00675 0.311
CLV_NRD_NRD_1 370 372 PF00675 0.396
CLV_NRD_NRD_1 406 408 PF00675 0.377
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I3J0 Leptomonas seymouri 96% 100%
A0A0S4IZR5 Bodo saltans 83% 97%
A0A1X0P5F3 Trypanosomatidae 88% 100%
A0A3S5H804 Leishmania donovani 100% 100%
A0A422N423 Trypanosoma rangeli 89% 100%
A4HN65 Leishmania braziliensis 99% 100%
C9ZYT6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 86% 100%
E9AFL9 Leishmania major 99% 100%
E9B6S2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 99% 100%
V5DUK9 Trypanosoma cruzi 88% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS