Sperm-tail_PG-rich_repeat

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Sperm-tail PG-rich repeat - putative

Species:

Leishmania infantum

UniProt:

A4IBT0_LEIIN

TriTrypDb:

LINF_350044700

Length:

476

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4IBT0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBT0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.610
CLV_NRD_NRD_1	111	113	PF00675	0.334
CLV_NRD_NRD_1	150	152	PF00675	0.336
CLV_NRD_NRD_1	163	165	PF00675	0.627
CLV_NRD_NRD_1	267	269	PF00675	0.592
CLV_NRD_NRD_1	304	306	PF00675	0.319
CLV_NRD_NRD_1	307	309	PF00675	0.307
CLV_NRD_NRD_1	352	354	PF00675	0.592
CLV_NRD_NRD_1	425	427	PF00675	0.668
CLV_PCSK_FUR_1	305	309	PF00082	0.355
CLV_PCSK_KEX2_1	150	152	PF00082	0.336
CLV_PCSK_KEX2_1	201	203	PF00082	0.639
CLV_PCSK_KEX2_1	267	269	PF00082	0.589
CLV_PCSK_KEX2_1	304	306	PF00082	0.355
CLV_PCSK_KEX2_1	307	309	PF00082	0.319
CLV_PCSK_KEX2_1	31	33	PF00082	0.363
CLV_PCSK_KEX2_1	352	354	PF00082	0.593
CLV_PCSK_KEX2_1	425	427	PF00082	0.697
CLV_PCSK_PC1ET2_1	201	203	PF00082	0.639
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.363
CLV_PCSK_PC1ET2_1	352	354	PF00082	0.691
CLV_PCSK_PC7_1	348	354	PF00082	0.644
DEG_APCC_KENBOX_2	9	13	PF00400	0.562
DEG_Nend_UBRbox_2	1	3	PF02207	0.716
DEG_SCF_TRCP1_1	129	135	PF00400	0.614
DEG_SPOP_SBC_1	273	277	PF00917	0.579
DOC_CDC14_PxL_1	1	9	PF14671	0.693
DOC_PP1_RVXF_1	432	439	PF00149	0.637
DOC_PP2B_LxvP_1	67	70	PF13499	0.499
DOC_PP4_FxxP_1	120	123	PF00568	0.536
DOC_PP4_FxxP_1	312	315	PF00568	0.724
DOC_PP4_FxxP_1	58	61	PF00568	0.371
DOC_PP4_MxPP_1	167	170	PF00568	0.487
DOC_USP7_MATH_1	123	127	PF00917	0.604
DOC_USP7_MATH_1	238	242	PF00917	0.557
DOC_USP7_MATH_1	273	277	PF00917	0.677
DOC_USP7_MATH_1	279	283	PF00917	0.618
DOC_USP7_MATH_1	317	321	PF00917	0.528
DOC_USP7_MATH_1	41	45	PF00917	0.475
DOC_USP7_MATH_1	81	85	PF00917	0.570
DOC_USP7_MATH_2	232	238	PF00917	0.689
DOC_WW_Pin1_4	210	215	PF00397	0.606
DOC_WW_Pin1_4	292	297	PF00397	0.677
DOC_WW_Pin1_4	323	328	PF00397	0.550
DOC_WW_Pin1_4	94	99	PF00397	0.572
LIG_14-3-3_CanoR_1	116	121	PF00244	0.481
LIG_14-3-3_CanoR_1	353	359	PF00244	0.544
LIG_14-3-3_CanoR_1	437	444	PF00244	0.607
LIG_14-3-3_CanoR_1	455	460	PF00244	0.587
LIG_BIR_III_4	253	257	PF00653	0.604
LIG_BRCT_BRCA1_1	116	120	PF00533	0.555
LIG_BRCT_BRCA1_1	192	196	PF00533	0.565
LIG_BRCT_BRCA1_1	242	246	PF00533	0.635
LIG_BRCT_BRCA1_1	276	280	PF00533	0.617
LIG_BRCT_BRCA1_1	71	75	PF00533	0.499
LIG_BRCT_BRCA1_1	78	82	PF00533	0.509
LIG_BRCT_BRCA1_1	85	89	PF00533	0.659
LIG_FHA_1	259	265	PF00498	0.564
LIG_FHA_1	403	409	PF00498	0.713
LIG_FHA_1	470	476	PF00498	0.619
LIG_FHA_1	72	78	PF00498	0.496
LIG_LIR_Apic_2	117	123	PF02991	0.536
LIG_LIR_Apic_2	378	384	PF02991	0.535
LIG_LIR_Apic_2	55	61	PF02991	0.645
LIG_LIR_Gen_1	282	292	PF02991	0.657
LIG_LIR_Gen_1	413	422	PF02991	0.697
LIG_LIR_Gen_1	435	444	PF02991	0.641
LIG_LIR_Nem_3	157	161	PF02991	0.597
LIG_LIR_Nem_3	177	181	PF02991	0.473
LIG_LIR_Nem_3	234	239	PF02991	0.617
LIG_LIR_Nem_3	282	287	PF02991	0.643
LIG_LIR_Nem_3	413	417	PF02991	0.703
LIG_LIR_Nem_3	435	441	PF02991	0.639
LIG_MLH1_MIPbox_1	243	247	PF16413	0.571
LIG_MYND_1	180	184	PF01753	0.601
LIG_Pex14_2	325	329	PF04695	0.666
LIG_PTB_Apo_2	139	146	PF02174	0.511
LIG_PTB_Phospho_1	139	145	PF10480	0.511
LIG_REV1ctd_RIR_1	244	254	PF16727	0.577
LIG_SH2_CRK	178	182	PF00017	0.489
LIG_SH2_CRK	64	68	PF00017	0.511
LIG_SH2_NCK_1	145	149	PF00017	0.536
LIG_SH2_SRC	219	222	PF00017	0.639
LIG_SH2_STAP1	124	128	PF00017	0.698
LIG_SH2_STAP1	377	381	PF00017	0.558
LIG_SH2_STAT5	118	121	PF00017	0.499
LIG_SH2_STAT5	235	238	PF00017	0.667
LIG_SH2_STAT5	260	263	PF00017	0.569
LIG_SH2_STAT5	311	314	PF00017	0.507
LIG_SH2_STAT5	414	417	PF00017	0.627
LIG_SH3_3	163	169	PF00018	0.654
LIG_SH3_3	405	411	PF00018	0.636
LIG_WRC_WIRS_1	355	360	PF05994	0.543
MOD_CK1_1	241	247	PF00069	0.664
MOD_CK1_1	272	278	PF00069	0.591
MOD_CK1_1	84	90	PF00069	0.580
MOD_CK2_1	410	416	PF00069	0.650
MOD_Cter_Amidation	162	165	PF01082	0.644
MOD_GlcNHglycan	120	123	PF01048	0.336
MOD_GlcNHglycan	125	128	PF01048	0.659
MOD_GlcNHglycan	129	132	PF01048	0.366
MOD_GlcNHglycan	161	164	PF01048	0.508
MOD_GlcNHglycan	236	239	PF01048	0.557
MOD_GlcNHglycan	271	274	PF01048	0.616
MOD_GlcNHglycan	276	279	PF01048	0.566
MOD_GlcNHglycan	281	284	PF01048	0.531
MOD_GlcNHglycan	340	343	PF01048	0.686
MOD_GlcNHglycan	345	348	PF01048	0.666
MOD_GlcNHglycan	366	369	PF01048	0.670
MOD_GlcNHglycan	444	447	PF01048	0.623
MOD_GlcNHglycan	52	55	PF01048	0.718
MOD_GSK3_1	114	121	PF00069	0.536
MOD_GSK3_1	123	130	PF00069	0.357
MOD_GSK3_1	14	21	PF00069	0.593
MOD_GSK3_1	191	198	PF00069	0.536
MOD_GSK3_1	234	241	PF00069	0.622
MOD_GSK3_1	269	276	PF00069	0.630
MOD_GSK3_1	323	330	PF00069	0.563
MOD_GSK3_1	332	339	PF00069	0.591
MOD_GSK3_1	385	392	PF00069	0.594
MOD_GSK3_1	417	424	PF00069	0.564
MOD_GSK3_1	460	467	PF00069	0.528
MOD_GSK3_1	99	106	PF00069	0.540
MOD_N-GLC_1	35	40	PF02516	0.304
MOD_N-GLC_1	390	395	PF02516	0.707
MOD_N-GLC_1	42	47	PF02516	0.460
MOD_N-GLC_1	464	469	PF02516	0.524
MOD_N-GLC_1	94	99	PF02516	0.572
MOD_NEK2_1	132	137	PF00069	0.591
MOD_NEK2_1	239	244	PF00069	0.531
MOD_NEK2_1	269	274	PF00069	0.489
MOD_NEK2_1	318	323	PF00069	0.609
MOD_NEK2_1	402	407	PF00069	0.627
MOD_NEK2_1	417	422	PF00069	0.578
MOD_NEK2_1	42	47	PF00069	0.631
MOD_NEK2_1	460	465	PF00069	0.540
MOD_PIKK_1	327	333	PF00454	0.699
MOD_PIKK_1	76	82	PF00454	0.699
MOD_PK_1	191	197	PF00069	0.577
MOD_PKA_2	14	20	PF00069	0.716
MOD_PKA_2	436	442	PF00069	0.629
MOD_PKA_2	454	460	PF00069	0.652
MOD_Plk_1	373	379	PF00069	0.688
MOD_Plk_1	390	396	PF00069	0.597
MOD_Plk_1	42	48	PF00069	0.707
MOD_Plk_1	464	470	PF00069	0.524
MOD_Plk_1	84	90	PF00069	0.580
MOD_Plk_4	191	197	PF00069	0.608
MOD_Plk_4	455	461	PF00069	0.517
MOD_Plk_4	469	475	PF00069	0.590
MOD_ProDKin_1	210	216	PF00069	0.612
MOD_ProDKin_1	292	298	PF00069	0.435
MOD_ProDKin_1	323	329	PF00069	0.557
MOD_ProDKin_1	94	100	PF00069	0.371
TRG_DiLeu_BaEn_2	84	90	PF01217	0.658
TRG_DiLeu_BaEn_4	2	8	PF01217	0.718
TRG_DiLeu_BaLyEn_6	177	182	PF01217	0.472
TRG_DiLeu_LyEn_5	2	7	PF01217	0.687
TRG_ENDOCYTIC_2	178	181	PF00928	0.521
TRG_ENDOCYTIC_2	284	287	PF00928	0.641
TRG_ENDOCYTIC_2	414	417	PF00928	0.676
TRG_ENDOCYTIC_2	64	67	PF00928	0.498
TRG_ER_diArg_1	150	152	PF00400	0.536
TRG_ER_diArg_1	266	268	PF00400	0.591
TRG_ER_diArg_1	304	307	PF00400	0.561
TRG_ER_diArg_1	425	427	PF00400	0.692
TRG_NLS_MonoExtC_3	351	356	PF00514	0.638
TRG_NLS_MonoExtN_4	350	357	PF00514	0.636

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAQ4	Leptomonas seymouri	60%	99%
A0A0S4IX55	Bodo saltans	30%	89%
A0A1X0P6L3	Trypanosomatidae	38%	100%
A0A3Q8IGK1	Leishmania donovani	99%	100%
A0A3R7LN85	Trypanosoma rangeli	35%	100%
A4HN63	Leishmania braziliensis	77%	100%
C9ZYT8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
E9AFL7	Leishmania major	93%	100%
E9B6S0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q08BC4	Danio rerio	29%	85%
Q8C8J0	Mus musculus	26%	85%
V5C2R9	Trypanosoma cruzi	36%	100%