Ufd2P_core domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IBS9_LEIIN

TriTrypDb:

LINF_350044600

Length:

804

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

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Expansion

Sequence features

A4IBS9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBS9

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	286	290	PF00656	0.424
CLV_NRD_NRD_1	179	181	PF00675	0.644
CLV_NRD_NRD_1	222	224	PF00675	0.635
CLV_NRD_NRD_1	377	379	PF00675	0.623
CLV_PCSK_KEX2_1	210	212	PF00082	0.539
CLV_PCSK_KEX2_1	277	279	PF00082	0.597
CLV_PCSK_PC1ET2_1	210	212	PF00082	0.585
CLV_PCSK_PC1ET2_1	277	279	PF00082	0.597
CLV_PCSK_SKI1_1	203	207	PF00082	0.519
CLV_PCSK_SKI1_1	305	309	PF00082	0.683

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IID0	Leptomonas seymouri	59%	100%
A0A0S4IXF5	Bodo saltans	23%	83%
A0A1X0P5G3	Trypanosomatidae	33%	99%
A0A3R7K1M8	Trypanosoma rangeli	33%	89%
A0A3S7X9Q6	Leishmania donovani	99%	100%
A4HN62	Leishmania braziliensis	82%	100%
C9ZYT9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	91%
E9AFL6	Leishmania major	95%	100%
E9B6R9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
V5BTB4	Trypanosoma cruzi	34%	100%

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