LeishMANIAdb
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Calmodulin-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Calmodulin-like protein
Gene product:
calmodulin-like protein
Species:
Leishmania infantum
UniProt:
A4IBS7_LEIIN
TriTrypDb:
LINF_350044300
Length:
139

Annotations

Annotations by Jardim et al.

Metal Binding, Calmodulin-like

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005815 microtubule organizing center 2 1
GO:0005930 axoneme 2 1
GO:0016459 myosin complex 2 1
GO:0016460 myosin II complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0036064 ciliary basal body 3 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4IBS7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBS7

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0005488 binding 1 11
GO:0005509 calcium ion binding 5 11
GO:0043167 ion binding 2 11
GO:0043169 cation binding 3 11
GO:0046872 metal ion binding 4 11
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_SKI1_1 2 6 PF00082 0.453
CLV_PCSK_SKI1_1 68 72 PF00082 0.312
DEG_Nend_UBRbox_1 1 4 PF02207 0.532
DOC_USP7_MATH_1 15 19 PF00917 0.428
DOC_USP7_UBL2_3 120 124 PF12436 0.408
DOC_USP7_UBL2_3 56 60 PF12436 0.517
LIG_14-3-3_CanoR_1 88 98 PF00244 0.312
LIG_APCC_ABBA_1 126 131 PF00400 0.531
LIG_FHA_1 79 85 PF00498 0.339
LIG_FHA_2 39 45 PF00498 0.446
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P206 Leptomonas seymouri 39% 93%
A0A0N0P4B4 Leptomonas seymouri 91% 96%
A0A0N0P8Y6 Leptomonas seymouri 27% 77%
A0A0S4INC8 Bodo saltans 27% 74%
A0A0S4IS38 Bodo saltans 39% 93%
A0A0S4IXG9 Bodo saltans 88% 96%
A0A0S4J7U6 Bodo saltans 33% 86%
A0A0S4JFC8 Bodo saltans 39% 82%
A0A0S4JFY6 Bodo saltans 33% 94%
A0A1X0NMM5 Trypanosomatidae 39% 93%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS