Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IBQ4_LEIIN

TriTrypDb:

LINF_350041900

Length:

672

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBQ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBQ4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	516	520	PF00656	0.847
CLV_MEL_PAP_1	357	363	PF00089	0.611
CLV_NRD_NRD_1	135	137	PF00675	0.819
CLV_NRD_NRD_1	182	184	PF00675	0.658
CLV_NRD_NRD_1	331	333	PF00675	0.843
CLV_NRD_NRD_1	388	390	PF00675	0.592
CLV_NRD_NRD_1	426	428	PF00675	0.824
CLV_NRD_NRD_1	460	462	PF00675	0.696
CLV_NRD_NRD_1	468	470	PF00675	0.739
CLV_NRD_NRD_1	514	516	PF00675	0.671
CLV_PCSK_KEX2_1	182	184	PF00082	0.649
CLV_PCSK_KEX2_1	331	333	PF00082	0.843
CLV_PCSK_KEX2_1	388	390	PF00082	0.592
CLV_PCSK_KEX2_1	426	428	PF00082	0.824
CLV_PCSK_KEX2_1	460	462	PF00082	0.696
CLV_PCSK_KEX2_1	467	469	PF00082	0.754
CLV_PCSK_KEX2_1	514	516	PF00082	0.671
CLV_PCSK_KEX2_1	662	664	PF00082	0.632
CLV_PCSK_PC1ET2_1	662	664	PF00082	0.632
CLV_PCSK_PC7_1	463	469	PF00082	0.812
CLV_PCSK_SKI1_1	305	309	PF00082	0.629
CLV_PCSK_SKI1_1	332	336	PF00082	0.840
CLV_PCSK_SKI1_1	388	392	PF00082	0.534
CLV_PCSK_SKI1_1	44	48	PF00082	0.688
CLV_PCSK_SKI1_1	50	54	PF00082	0.613
DEG_APCC_DBOX_1	304	312	PF00400	0.725
DEG_Nend_Nbox_1	1	3	PF02207	0.542
DEG_SPOP_SBC_1	294	298	PF00917	0.782
DEG_SPOP_SBC_1	349	353	PF00917	0.655
DEG_SPOP_SBC_1	370	374	PF00917	0.821
DOC_CKS1_1	174	179	PF01111	0.649
DOC_CKS1_1	3	8	PF01111	0.793
DOC_CYCLIN_yCln2_LP_2	174	180	PF00134	0.821
DOC_CYCLIN_yCln2_LP_2	280	283	PF00134	0.623
DOC_CYCLIN_yCln2_LP_2	504	510	PF00134	0.745
DOC_MAPK_DCC_7	305	313	PF00069	0.634
DOC_MAPK_gen_1	660	670	PF00069	0.462
DOC_MAPK_MEF2A_6	305	313	PF00069	0.759
DOC_MAPK_MEF2A_6	611	620	PF00069	0.692
DOC_PP2B_LxvP_1	234	237	PF13499	0.566
DOC_PP2B_LxvP_1	280	283	PF13499	0.673
DOC_USP7_MATH_1	114	118	PF00917	0.768
DOC_USP7_MATH_1	156	160	PF00917	0.686
DOC_USP7_MATH_1	167	171	PF00917	0.665
DOC_USP7_MATH_1	178	182	PF00917	0.617
DOC_USP7_MATH_1	205	209	PF00917	0.656
DOC_USP7_MATH_1	255	259	PF00917	0.660
DOC_USP7_MATH_1	294	298	PF00917	0.801
DOC_USP7_MATH_1	339	343	PF00917	0.821
DOC_USP7_MATH_1	378	382	PF00917	0.712
DOC_USP7_MATH_1	513	517	PF00917	0.831
DOC_USP7_MATH_1	563	567	PF00917	0.777
DOC_USP7_MATH_1	648	652	PF00917	0.660
DOC_WW_Pin1_4	120	125	PF00397	0.778
DOC_WW_Pin1_4	173	178	PF00397	0.676
DOC_WW_Pin1_4	2	7	PF00397	0.793
DOC_WW_Pin1_4	227	232	PF00397	0.832
DOC_WW_Pin1_4	238	243	PF00397	0.666
DOC_WW_Pin1_4	26	31	PF00397	0.818
DOC_WW_Pin1_4	296	301	PF00397	0.661
DOC_WW_Pin1_4	323	328	PF00397	0.743
DOC_WW_Pin1_4	382	387	PF00397	0.821
DOC_WW_Pin1_4	410	415	PF00397	0.748
DOC_WW_Pin1_4	419	424	PF00397	0.633
DOC_WW_Pin1_4	444	449	PF00397	0.840
DOC_WW_Pin1_4	488	493	PF00397	0.611
DOC_WW_Pin1_4	509	514	PF00397	0.777
DOC_WW_Pin1_4	90	95	PF00397	0.627
LIG_14-3-3_CanoR_1	144	153	PF00244	0.809
LIG_14-3-3_CanoR_1	22	30	PF00244	0.811
LIG_14-3-3_CanoR_1	295	300	PF00244	0.800
LIG_14-3-3_CanoR_1	331	337	PF00244	0.786
LIG_14-3-3_CanoR_1	360	368	PF00244	0.626
LIG_14-3-3_CanoR_1	460	466	PF00244	0.786
LIG_14-3-3_CanoR_1	467	475	PF00244	0.721
LIG_14-3-3_CanoR_1	509	513	PF00244	0.764
LIG_14-3-3_CanoR_1	63	71	PF00244	0.659
LIG_14-3-3_CanoR_1	663	669	PF00244	0.636
LIG_Actin_WH2_2	112	128	PF00022	0.551
LIG_BRCT_BRCA1_1	92	96	PF00533	0.627
LIG_CSL_BTD_1	275	278	PF09270	0.825
LIG_FHA_1	146	152	PF00498	0.807
LIG_FHA_1	202	208	PF00498	0.648
LIG_FHA_1	213	219	PF00498	0.666
LIG_FHA_1	283	289	PF00498	0.810
LIG_FHA_1	297	303	PF00498	0.585
LIG_FHA_1	407	413	PF00498	0.776
LIG_FHA_1	460	466	PF00498	0.773
LIG_FHA_1	574	580	PF00498	0.589
LIG_FHA_2	531	537	PF00498	0.655
LIG_FHA_2	650	656	PF00498	0.604
LIG_LIR_Gen_1	528	539	PF02991	0.650
LIG_LIR_Nem_3	362	368	PF02991	0.805
LIG_LIR_Nem_3	384	390	PF02991	0.643
LIG_LIR_Nem_3	528	534	PF02991	0.658
LIG_LIR_Nem_3	626	631	PF02991	0.676
LIG_MYND_1	278	282	PF01753	0.631
LIG_NRBOX	189	195	PF00104	0.739
LIG_RPA_C_Fungi	464	476	PF08784	0.749
LIG_SH2_CRK	387	391	PF00017	0.640
LIG_SH2_CRK	418	422	PF00017	0.813
LIG_SH2_PTP2	529	532	PF00017	0.652
LIG_SH2_SRC	365	368	PF00017	0.812
LIG_SH2_STAT5	400	403	PF00017	0.730
LIG_SH2_STAT5	481	484	PF00017	0.792
LIG_SH2_STAT5	529	532	PF00017	0.652
LIG_SH2_STAT5	597	600	PF00017	0.646
LIG_SH2_STAT5	657	660	PF00017	0.630
LIG_SH2_STAT5	664	667	PF00017	0.511
LIG_SH3_3	108	114	PF00018	0.733
LIG_SH3_3	121	127	PF00018	0.699
LIG_SH3_3	150	156	PF00018	0.798
LIG_SH3_3	182	188	PF00018	0.649
LIG_SH3_3	3	9	PF00018	0.660
LIG_SH3_3	303	309	PF00018	0.753
LIG_SH3_3	507	513	PF00018	0.755
LIG_SH3_3	537	543	PF00018	0.621
LIG_SUMO_SIM_anti_2	614	621	PF11976	0.716
LIG_SUMO_SIM_par_1	148	154	PF11976	0.627
LIG_TRAF2_1	242	245	PF00917	0.663
LIG_TYR_ITIM	416	421	PF00017	0.810
LIG_WRC_WIRS_1	583	588	PF05994	0.663
LIG_WW_3	320	324	PF00397	0.834
MOD_CDC14_SPxK_1	123	126	PF00782	0.780
MOD_CDC14_SPxK_1	385	388	PF00782	0.593
MOD_CDC14_SPxK_1	512	515	PF00782	0.640
MOD_CDK_SPK_2	238	243	PF00069	0.794
MOD_CDK_SPK_2	410	415	PF00069	0.783
MOD_CDK_SPK_2	509	514	PF00069	0.777
MOD_CDK_SPxK_1	120	126	PF00069	0.781
MOD_CDK_SPxK_1	382	388	PF00069	0.596
MOD_CDK_SPxK_1	509	515	PF00069	0.612
MOD_CDK_SPxxK_3	382	389	PF00069	0.821
MOD_CDK_SPxxK_3	419	426	PF00069	0.818
MOD_CK1_1	117	123	PF00069	0.793
MOD_CK1_1	159	165	PF00069	0.685
MOD_CK1_1	206	212	PF00069	0.723
MOD_CK1_1	214	220	PF00069	0.644
MOD_CK1_1	230	236	PF00069	0.689
MOD_CK1_1	238	244	PF00069	0.714
MOD_CK1_1	26	32	PF00069	0.570
MOD_CK1_1	359	365	PF00069	0.783
MOD_CK1_1	381	387	PF00069	0.823
MOD_CK1_1	410	416	PF00069	0.622
MOD_CK1_1	444	450	PF00069	0.839
MOD_CK1_1	471	477	PF00069	0.791
MOD_CK1_1	8	14	PF00069	0.711
MOD_CK2_1	238	244	PF00069	0.766
MOD_CK2_1	28	34	PF00069	0.822
MOD_CK2_1	360	366	PF00069	0.748
MOD_CK2_1	530	536	PF00069	0.654
MOD_CK2_1	649	655	PF00069	0.606
MOD_Cter_Amidation	134	137	PF01082	0.827
MOD_Cter_Amidation	465	468	PF01082	0.810
MOD_DYRK1A_RPxSP_1	419	423	PF00069	0.689
MOD_DYRK1A_RPxSP_1	509	513	PF00069	0.764
MOD_GlcNHglycan	116	119	PF01048	0.552
MOD_GlcNHglycan	127	130	PF01048	0.656
MOD_GlcNHglycan	133	136	PF01048	0.590
MOD_GlcNHglycan	169	172	PF01048	0.805
MOD_GlcNHglycan	201	204	PF01048	0.747
MOD_GlcNHglycan	218	221	PF01048	0.640
MOD_GlcNHglycan	237	240	PF01048	0.690
MOD_GlcNHglycan	258	261	PF01048	0.835
MOD_GlcNHglycan	30	33	PF01048	0.820
MOD_GlcNHglycan	362	365	PF01048	0.754
MOD_GlcNHglycan	380	383	PF01048	0.579
MOD_GlcNHglycan	394	397	PF01048	0.547
MOD_GlcNHglycan	443	446	PF01048	0.848
MOD_GlcNHglycan	449	452	PF01048	0.733
MOD_GlcNHglycan	515	518	PF01048	0.720
MOD_GlcNHglycan	56	59	PF01048	0.695
MOD_GlcNHglycan	565	568	PF01048	0.777
MOD_GlcNHglycan	573	576	PF01048	0.651
MOD_GlcNHglycan	81	84	PF01048	0.695
MOD_GlcNHglycan	99	102	PF01048	0.663
MOD_GSK3_1	114	121	PF00069	0.784
MOD_GSK3_1	156	163	PF00069	0.669
MOD_GSK3_1	195	202	PF00069	0.640
MOD_GSK3_1	208	215	PF00069	0.602
MOD_GSK3_1	323	330	PF00069	0.856
MOD_GSK3_1	340	347	PF00069	0.544
MOD_GSK3_1	356	363	PF00069	0.701
MOD_GSK3_1	369	376	PF00069	0.563
MOD_GSK3_1	378	385	PF00069	0.680
MOD_GSK3_1	4	11	PF00069	0.571
MOD_GSK3_1	406	413	PF00069	0.776
MOD_GSK3_1	431	438	PF00069	0.832
MOD_GSK3_1	488	495	PF00069	0.610
MOD_GSK3_1	50	57	PF00069	0.688
MOD_GSK3_1	509	516	PF00069	0.786
MOD_GSK3_1	571	578	PF00069	0.789
MOD_GSK3_1	86	93	PF00069	0.802
MOD_N-GLC_1	167	172	PF02516	0.819
MOD_N-GLC_1	525	530	PF02516	0.521
MOD_N-GLC_1	649	654	PF02516	0.604
MOD_N-GLC_2	548	550	PF02516	0.512
MOD_NEK2_1	151	156	PF00069	0.797
MOD_NEK2_1	160	165	PF00069	0.663
MOD_NEK2_1	25	30	PF00069	0.785
MOD_NEK2_1	348	353	PF00069	0.632
MOD_NEK2_1	40	45	PF00069	0.601
MOD_NEK2_1	417	422	PF00069	0.685
MOD_NEK2_2	664	669	PF00069	0.630
MOD_PIKK_1	23	29	PF00454	0.777
MOD_PK_1	461	467	PF00069	0.646
MOD_PKA_1	468	474	PF00069	0.743
MOD_PKA_2	125	131	PF00069	0.670
MOD_PKA_2	143	149	PF00069	0.681
MOD_PKA_2	15	21	PF00069	0.826
MOD_PKA_2	294	300	PF00069	0.776
MOD_PKA_2	359	365	PF00069	0.615
MOD_PKA_2	40	46	PF00069	0.809
MOD_PKA_2	459	465	PF00069	0.666
MOD_PKA_2	468	474	PF00069	0.665
MOD_PKA_2	508	514	PF00069	0.769
MOD_PKA_2	607	613	PF00069	0.648
MOD_PKB_1	263	271	PF00069	0.655
MOD_PKB_1	323	331	PF00069	0.754
MOD_PKB_1	439	447	PF00069	0.848
MOD_PKB_1	467	475	PF00069	0.747
MOD_PKB_1	627	635	PF00069	0.645
MOD_Plk_1	151	157	PF00069	0.621
MOD_Plk_1	370	376	PF00069	0.820
MOD_Plk_1	525	531	PF00069	0.514
MOD_Plk_4	146	152	PF00069	0.632
MOD_Plk_4	156	162	PF00069	0.550
MOD_Plk_4	230	236	PF00069	0.664
MOD_Plk_4	492	498	PF00069	0.785
MOD_Plk_4	525	531	PF00069	0.689
MOD_ProDKin_1	120	126	PF00069	0.781
MOD_ProDKin_1	173	179	PF00069	0.675
MOD_ProDKin_1	2	8	PF00069	0.793
MOD_ProDKin_1	227	233	PF00069	0.833
MOD_ProDKin_1	238	244	PF00069	0.665
MOD_ProDKin_1	26	32	PF00069	0.820
MOD_ProDKin_1	296	302	PF00069	0.658
MOD_ProDKin_1	323	329	PF00069	0.744
MOD_ProDKin_1	382	388	PF00069	0.821
MOD_ProDKin_1	410	416	PF00069	0.749
MOD_ProDKin_1	419	425	PF00069	0.635
MOD_ProDKin_1	444	450	PF00069	0.839
MOD_ProDKin_1	488	494	PF00069	0.611
MOD_ProDKin_1	509	515	PF00069	0.787
MOD_ProDKin_1	90	96	PF00069	0.628
MOD_SUMO_for_1	242	245	PF00179	0.663
TRG_DiLeu_BaEn_1	169	174	PF01217	0.651
TRG_DiLeu_BaEn_1	552	557	PF01217	0.571
TRG_DiLeu_BaEn_1	614	619	PF01217	0.714
TRG_DiLeu_BaEn_4	552	558	PF01217	0.574
TRG_DiLeu_BaLyEn_6	41	46	PF01217	0.637
TRG_DiLeu_BaLyEn_6	489	494	PF01217	0.787
TRG_DiLeu_BaLyEn_6	613	618	PF01217	0.700
TRG_ENDOCYTIC_2	365	368	PF00928	0.812
TRG_ENDOCYTIC_2	387	390	PF00928	0.645
TRG_ENDOCYTIC_2	418	421	PF00928	0.817
TRG_ENDOCYTIC_2	529	532	PF00928	0.652
TRG_ER_diArg_1	182	184	PF00400	0.653
TRG_ER_diArg_1	19	22	PF00400	0.714
TRG_ER_diArg_1	387	389	PF00400	0.597
TRG_ER_diArg_1	425	427	PF00400	0.831
TRG_ER_diArg_1	460	463	PF00400	0.741
TRG_ER_diArg_1	467	469	PF00400	0.704
TRG_ER_diArg_1	478	481	PF00400	0.547
TRG_ER_diArg_1	513	515	PF00400	0.650
TRG_Pf-PMV_PEXEL_1	74	79	PF00026	0.638

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIL4	Leishmania donovani	97%	78%
E9AFI9	Leishmania major	84%	100%
E9B6P4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%