LeishMANIAdb
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NET domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
NET domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IBQ3_LEIIN
TriTrypDb:
LINF_350041800
Length:
204

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBQ3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBQ3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 164 168 PF00656 0.771
CLV_C14_Caspase3-7 6 10 PF00656 0.486
CLV_NRD_NRD_1 126 128 PF00675 0.535
CLV_NRD_NRD_1 198 200 PF00675 0.684
CLV_NRD_NRD_1 7 9 PF00675 0.491
CLV_PCSK_KEX2_1 126 128 PF00082 0.559
CLV_PCSK_KEX2_1 197 199 PF00082 0.692
CLV_PCSK_KEX2_1 7 9 PF00082 0.491
CLV_PCSK_PC7_1 3 9 PF00082 0.500
DOC_PP2B_LxvP_1 113 116 PF13499 0.580
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PBI1 Leptomonas seymouri 45% 92%
A0A1X0P5H7 Trypanosomatidae 34% 100%
A0A3Q8IMQ4 Leishmania donovani 99% 100%
A0A422NR35 Trypanosoma rangeli 37% 100%
A4HN35 Leishmania braziliensis 71% 99%
C9ZYX2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 81%
E9AFI8 Leishmania major 89% 99%
E9B6P3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 99%
V5BD49 Trypanosoma cruzi 35% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS