Reverse transcriptase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc finger protein - putative

Species:

Leishmania infantum

UniProt:

A4IBP0_LEIIN

TriTrypDb:

LINF_350040400

Length:

222

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4IBP0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBP0

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	3
GO:0043167	ion binding	2	3
GO:0043169	cation binding	3	3
GO:0046872	metal ion binding	4	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	82	86	PF00656	0.645
CLV_NRD_NRD_1	65	67	PF00675	0.622
CLV_PCSK_SKI1_1	106	110	PF00082	0.561
CLV_PCSK_SKI1_1	117	121	PF00082	0.443
CLV_PCSK_SKI1_1	201	205	PF00082	0.636
DOC_CYCLIN_yCln2_LP_2	177	183	PF00134	0.519
DOC_MAPK_DCC_7	175	183	PF00069	0.521
DOC_MAPK_MEF2A_6	117	125	PF00069	0.549
DOC_PP2B_LxvP_1	164	167	PF13499	0.652
DOC_USP7_MATH_1	2	6	PF00917	0.739
DOC_USP7_MATH_1	40	44	PF00917	0.711
DOC_USP7_MATH_1	52	56	PF00917	0.658
DOC_WW_Pin1_4	97	102	PF00397	0.646
LIG_14-3-3_CanoR_1	112	117	PF00244	0.557
LIG_14-3-3_CanoR_1	41	48	PF00244	0.798
LIG_BIR_II_1	1	5	PF00653	0.515
LIG_BIR_III_4	44	48	PF00653	0.703
LIG_BIR_III_4	87	91	PF00653	0.621
LIG_EVH1_1	164	168	PF00568	0.661
LIG_FHA_1	118	124	PF00498	0.549
LIG_FHA_1	143	149	PF00498	0.698
LIG_FHA_1	159	165	PF00498	0.647
LIG_FHA_1	206	212	PF00498	0.710
LIG_FHA_2	135	141	PF00498	0.759
LIG_FHA_2	187	193	PF00498	0.706
LIG_FHA_2	55	61	PF00498	0.704
LIG_GBD_Chelix_1	194	202	PF00786	0.565
LIG_LIR_Gen_1	120	127	PF02991	0.555
LIG_LIR_Gen_1	69	80	PF02991	0.635
LIG_LIR_Nem_3	120	125	PF02991	0.553
LIG_LIR_Nem_3	217	222	PF02991	0.642
LIG_LIR_Nem_3	69	75	PF02991	0.611
LIG_SH2_CRK	72	76	PF00017	0.760
LIG_SH2_GRB2like	72	75	PF00017	0.753
LIG_SH2_PTP2	122	125	PF00017	0.559
LIG_SH2_SRC	122	125	PF00017	0.559
LIG_SH2_STAT5	122	125	PF00017	0.535
LIG_SH2_STAT5	176	179	PF00017	0.639
LIG_SH3_1	162	168	PF00018	0.663
LIG_SH3_3	149	155	PF00018	0.643
LIG_SH3_3	162	168	PF00018	0.653
LIG_SH3_CIN85_PxpxPR_1	36	41	PF14604	0.680
LIG_SUMO_SIM_anti_2	179	185	PF11976	0.520
LIG_TYR_ITSM	118	125	PF00017	0.551
MOD_CK1_1	142	148	PF00069	0.637
MOD_CK1_1	4	10	PF00069	0.665
MOD_CK2_1	134	140	PF00069	0.747
MOD_CK2_1	186	192	PF00069	0.709
MOD_CK2_1	54	60	PF00069	0.688
MOD_GlcNHglycan	172	175	PF01048	0.612
MOD_GlcNHglycan	36	39	PF01048	0.773
MOD_GSK3_1	142	149	PF00069	0.667
MOD_GSK3_1	201	208	PF00069	0.654
MOD_GSK3_1	91	98	PF00069	0.684
MOD_NEK2_1	1	6	PF00069	0.675
MOD_PKA_2	142	148	PF00069	0.659
MOD_PKA_2	40	46	PF00069	0.751
MOD_Plk_2-3	146	152	PF00069	0.671
MOD_Plk_4	10	16	PF00069	0.549
MOD_Plk_4	117	123	PF00069	0.487
MOD_Plk_4	179	185	PF00069	0.520
MOD_ProDKin_1	97	103	PF00069	0.636
TRG_DiLeu_BaEn_1	105	110	PF01217	0.559
TRG_ENDOCYTIC_2	122	125	PF00928	0.559
TRG_ENDOCYTIC_2	72	75	PF00928	0.623
TRG_Pf-PMV_PEXEL_1	175	179	PF00026	0.639

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9N1	Leptomonas seymouri	52%	73%
A0A3Q8II84	Leishmania donovani	99%	100%
A4HN19	Leishmania braziliensis	74%	100%
E9AFH4	Leishmania major	92%	100%
E9B6M9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%