LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IBN1_LEIIN
TriTrypDb:
LINF_350039500 *
Length:
718

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 9
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBN1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBN1

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 188 190 PF00675 0.721
CLV_NRD_NRD_1 476 478 PF00675 0.467
CLV_NRD_NRD_1 669 671 PF00675 0.520
CLV_NRD_NRD_1 713 715 PF00675 0.714
CLV_NRD_NRD_1 90 92 PF00675 0.750
CLV_PCSK_FUR_1 473 477 PF00082 0.484
CLV_PCSK_FUR_1 667 671 PF00082 0.568
CLV_PCSK_KEX2_1 188 190 PF00082 0.724
CLV_PCSK_KEX2_1 475 477 PF00082 0.483
CLV_PCSK_KEX2_1 478 480 PF00082 0.444
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HUU2 Leptomonas seymouri 53% 100%
A0A1X0P6R1 Trypanosomatidae 30% 100%
A0A3Q8IMM0 Leishmania donovani 99% 100%
A0A3R7L599 Trypanosoma rangeli 31% 100%
A4HN08 Leishmania braziliensis 81% 100%
C9ZZ00 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
E9AFG5 Leishmania major 94% 100%
E9B6M0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
V5BY91 Trypanosoma cruzi 32% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS