Putative 60S ribosomal subunit protein L31

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal subunit protein L31 - putative

Species:

Leishmania infantum

UniProt:

A4IBL9_LEIIN

TriTrypDb:

LINF_350038300

Length:

183

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S ribosomal L31

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 8

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	13
GO:0032991	protein-containing complex	1	14
GO:0043226	organelle	2	14
GO:0043228	non-membrane-bounded organelle	3	14
GO:0043229	intracellular organelle	3	14
GO:0043232	intracellular non-membrane-bounded organelle	4	14
GO:0110165	cellular anatomical entity	1	14
GO:1990904	ribonucleoprotein complex	2	14
GO:0005730	nucleolus	5	1
GO:0005737	cytoplasm	2	1
GO:0015934	large ribosomal subunit	4	1
GO:0022625	cytosolic large ribosomal subunit	5	1
GO:0044391	ribosomal subunit	3	1

Expansion

Sequence features

A4IBL9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBL9

PDB structure(s): 6az3_e

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	14
GO:0006518	peptide metabolic process	4	14
GO:0006807	nitrogen compound metabolic process	2	14
GO:0008152	metabolic process	1	14
GO:0009058	biosynthetic process	2	14
GO:0009059	macromolecule biosynthetic process	4	14
GO:0009987	cellular process	1	14
GO:0019538	protein metabolic process	3	14
GO:0034641	cellular nitrogen compound metabolic process	3	14
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	14
GO:0043043	peptide biosynthetic process	5	14
GO:0043170	macromolecule metabolic process	3	14
GO:0043603	amide metabolic process	3	14
GO:0043604	amide biosynthetic process	4	14
GO:0044237	cellular metabolic process	2	14
GO:0044238	primary metabolic process	2	14
GO:0044249	cellular biosynthetic process	3	14
GO:0044260	obsolete cellular macromolecule metabolic process	3	14
GO:0044271	cellular nitrogen compound biosynthetic process	4	14
GO:0071704	organic substance metabolic process	2	14
GO:1901564	organonitrogen compound metabolic process	3	14
GO:1901566	organonitrogen compound biosynthetic process	4	14
GO:1901576	organic substance biosynthetic process	3	14
GO:0002181	cytoplasmic translation	5	1

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	14
GO:0005198	structural molecule activity	1	14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	147	149	PF00675	0.326
CLV_NRD_NRD_1	17	19	PF00675	0.544
CLV_NRD_NRD_1	24	26	PF00675	0.569
CLV_NRD_NRD_1	44	46	PF00675	0.620
CLV_NRD_NRD_1	68	70	PF00675	0.531
CLV_NRD_NRD_1	73	75	PF00675	0.512
CLV_PCSK_FUR_1	32	36	PF00082	0.546
CLV_PCSK_KEX2_1	105	107	PF00082	0.321
CLV_PCSK_KEX2_1	31	33	PF00082	0.548
CLV_PCSK_KEX2_1	34	36	PF00082	0.530
CLV_PCSK_KEX2_1	44	46	PF00082	0.358
CLV_PCSK_KEX2_1	70	72	PF00082	0.592
CLV_PCSK_KEX2_1	98	100	PF00082	0.319
CLV_PCSK_PC1ET2_1	105	107	PF00082	0.321
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.569
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.525
CLV_PCSK_PC1ET2_1	44	46	PF00082	0.358
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.592
CLV_PCSK_PC1ET2_1	98	100	PF00082	0.319
CLV_PCSK_SKI1_1	105	109	PF00082	0.306
CLV_PCSK_SKI1_1	113	117	PF00082	0.295
CLV_PCSK_SKI1_1	133	137	PF00082	0.146
CLV_PCSK_SKI1_1	174	178	PF00082	0.428
CLV_PCSK_SKI1_1	34	38	PF00082	0.522
CLV_PCSK_SKI1_1	61	65	PF00082	0.540
CLV_PCSK_SKI1_1	89	93	PF00082	0.306
DEG_Nend_UBRbox_1	1	4	PF02207	0.452
DOC_MAPK_gen_1	98	104	PF00069	0.306
DOC_USP7_MATH_1	169	173	PF00917	0.441
DOC_USP7_MATH_1	55	59	PF00917	0.574
DOC_USP7_UBL2_3	4	8	PF12436	0.531
DOC_USP7_UBL2_3	89	93	PF12436	0.313
DOC_USP7_UBL2_3	94	98	PF12436	0.310
LIG_14-3-3_CanoR_1	65	69	PF00244	0.613
LIG_FHA_1	176	182	PF00498	0.450
LIG_FHA_1	82	88	PF00498	0.320
LIG_LIR_Nem_3	172	176	PF02991	0.433
LIG_LIR_Nem_3	30	36	PF02991	0.548
LIG_NRBOX	86	92	PF00104	0.306
LIG_SH2_CRK	162	166	PF00017	0.353
LIG_SH2_NCK_1	162	166	PF00017	0.353
LIG_SH2_STAT5	129	132	PF00017	0.320
LIG_SH2_STAT5	162	165	PF00017	0.354
LIG_WRC_WIRS_1	170	175	PF05994	0.434
MOD_CK1_1	125	131	PF00069	0.306
MOD_CK1_1	150	156	PF00069	0.431
MOD_Cter_Amidation	72	75	PF01082	0.515
MOD_GSK3_1	51	58	PF00069	0.548
MOD_GSK3_1	77	84	PF00069	0.292
MOD_NEK2_1	81	86	PF00069	0.353
MOD_NEK2_2	169	174	PF00069	0.448
MOD_PKA_1	69	75	PF00069	0.511
MOD_PKA_1	92	98	PF00069	0.306
MOD_PKA_2	147	153	PF00069	0.326
MOD_PKA_2	64	70	PF00069	0.566
MOD_PKB_1	59	67	PF00069	0.548
MOD_Plk_1	122	128	PF00069	0.306
MOD_Plk_1	81	87	PF00069	0.317
MOD_Plk_2-3	77	83	PF00069	0.335
MOD_Plk_4	125	131	PF00069	0.325
MOD_Plk_4	160	166	PF00069	0.355
TRG_ENDOCYTIC_2	162	165	PF00928	0.354
TRG_ER_diArg_1	141	144	PF00400	0.315
TRG_ER_diArg_1	68	71	PF00400	0.551
TRG_NLS_Bipartite_1	31	49	PF00514	0.546
TRG_NLS_Bipartite_1	74	96	PF00514	0.306
TRG_NLS_MonoExtN_4	44	49	PF00514	0.535
TRG_NLS_MonoExtN_4	89	96	PF00514	0.306
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.445

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0D7	Leptomonas seymouri	98%	100%
A0A1X0P5A7	Trypanosomatidae	81%	97%
A0A3Q8IJL7	Leishmania donovani	100%	97%
A0A3R7MZQ5	Trypanosoma rangeli	83%	100%
A0A3R7NE06	Trypanosoma rangeli	81%	100%
A0A3R7R8B8	Trypanosoma rangeli	81%	97%
A4HMZ5	Leishmania braziliensis	93%	100%
C9ZZ18	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	97%
E9AFF2	Leishmania major	99%	100%
E9AHW6	Leishmania infantum	100%	80%
E9B6K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
V5C333	Trypanosoma cruzi	81%	97%