Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

class I transcription factor A - subunit 2 - putative

Species:

Leishmania infantum

UniProt:

A4IBK6_LEIIN

TriTrypDb:

LINF_350036800

Length:

514

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBK6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBK6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	402	406	PF00656	0.751
CLV_NRD_NRD_1	143	145	PF00675	0.654
CLV_NRD_NRD_1	223	225	PF00675	0.574
CLV_NRD_NRD_1	246	248	PF00675	0.508
CLV_NRD_NRD_1	292	294	PF00675	0.690
CLV_NRD_NRD_1	313	315	PF00675	0.613
CLV_NRD_NRD_1	372	374	PF00675	0.724
CLV_NRD_NRD_1	433	435	PF00675	0.712
CLV_NRD_NRD_1	483	485	PF00675	0.610
CLV_NRD_NRD_1	493	495	PF00675	0.550
CLV_NRD_NRD_1	91	93	PF00675	0.741
CLV_PCSK_KEX2_1	143	145	PF00082	0.654
CLV_PCSK_KEX2_1	223	225	PF00082	0.499
CLV_PCSK_KEX2_1	246	248	PF00082	0.509
CLV_PCSK_KEX2_1	313	315	PF00082	0.593
CLV_PCSK_KEX2_1	34	36	PF00082	0.601
CLV_PCSK_KEX2_1	359	361	PF00082	0.765
CLV_PCSK_KEX2_1	433	435	PF00082	0.712
CLV_PCSK_KEX2_1	482	484	PF00082	0.657
CLV_PCSK_KEX2_1	493	495	PF00082	0.546
CLV_PCSK_KEX2_1	91	93	PF00082	0.729
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.601
CLV_PCSK_PC1ET2_1	359	361	PF00082	0.765
CLV_PCSK_PC7_1	355	361	PF00082	0.766
CLV_PCSK_PC7_1	489	495	PF00082	0.636
CLV_PCSK_SKI1_1	115	119	PF00082	0.563
CLV_PCSK_SKI1_1	134	138	PF00082	0.601
CLV_PCSK_SKI1_1	267	271	PF00082	0.548
CLV_PCSK_SKI1_1	313	317	PF00082	0.646
CLV_PCSK_SKI1_1	493	497	PF00082	0.610
CLV_PCSK_SKI1_1	86	90	PF00082	0.729
DEG_APCC_DBOX_1	226	234	PF00400	0.596
DEG_APCC_DBOX_1	376	384	PF00400	0.567
DEG_SPOP_SBC_1	420	424	PF00917	0.717
DOC_CKS1_1	268	273	PF01111	0.615
DOC_CYCLIN_RxL_1	215	226	PF00134	0.579
DOC_MAPK_gen_1	313	321	PF00069	0.635
DOC_MAPK_gen_1	373	383	PF00069	0.733
DOC_MAPK_MEF2A_6	465	474	PF00069	0.701
DOC_PP1_RVXF_1	216	223	PF00149	0.535
DOC_PP1_RVXF_1	84	91	PF00149	0.684
DOC_PP2B_LxvP_1	13	16	PF13499	0.505
DOC_PP2B_LxvP_1	472	475	PF13499	0.755
DOC_USP7_MATH_1	166	170	PF00917	0.752
DOC_USP7_MATH_1	364	368	PF00917	0.745
DOC_USP7_MATH_1	54	58	PF00917	0.750
DOC_USP7_MATH_1	62	66	PF00917	0.552
DOC_WW_Pin1_4	267	272	PF00397	0.609
DOC_WW_Pin1_4	282	287	PF00397	0.616
DOC_WW_Pin1_4	414	419	PF00397	0.747
DOC_WW_Pin1_4	97	102	PF00397	0.513
LIG_14-3-3_CanoR_1	115	125	PF00244	0.543
LIG_14-3-3_CanoR_1	128	132	PF00244	0.374
LIG_14-3-3_CanoR_1	181	191	PF00244	0.707
LIG_14-3-3_CanoR_1	234	244	PF00244	0.702
LIG_14-3-3_CanoR_1	291	299	PF00244	0.582
LIG_14-3-3_CanoR_1	313	321	PF00244	0.719
LIG_14-3-3_CanoR_1	362	372	PF00244	0.722
LIG_14-3-3_CanoR_1	506	511	PF00244	0.713
LIG_deltaCOP1_diTrp_1	432	442	PF00928	0.706
LIG_FHA_1	165	171	PF00498	0.721
LIG_FHA_1	314	320	PF00498	0.722
LIG_FHA_1	415	421	PF00498	0.677
LIG_FHA_1	424	430	PF00498	0.642
LIG_FHA_1	443	449	PF00498	0.464
LIG_FHA_1	79	85	PF00498	0.657
LIG_FHA_2	163	169	PF00498	0.719
LIG_FHA_2	208	214	PF00498	0.541
LIG_FHA_2	321	327	PF00498	0.684
LIG_GBD_Chelix_1	104	112	PF00786	0.551
LIG_LIR_Gen_1	256	265	PF02991	0.564
LIG_LIR_Nem_3	130	136	PF02991	0.567
LIG_LIR_Nem_3	219	225	PF02991	0.600
LIG_LIR_Nem_3	256	262	PF02991	0.560
LIG_NRBOX	379	385	PF00104	0.574
LIG_Pex14_2	259	263	PF04695	0.558
LIG_RPA_C_Fungi	213	225	PF08784	0.529
LIG_SH2_CRK	245	249	PF00017	0.558
LIG_SH2_CRK	468	472	PF00017	0.759
LIG_SH2_CRK	492	496	PF00017	0.672
LIG_SH3_2	16	21	PF14604	0.635
LIG_SH3_3	13	19	PF00018	0.618
LIG_SH3_3	91	97	PF00018	0.584
LIG_SUMO_SIM_par_1	247	253	PF11976	0.562
LIG_SUMO_SIM_par_1	326	334	PF11976	0.572
LIG_SxIP_EBH_1	52	66	PF03271	0.663
LIG_TYR_ITIM	243	248	PF00017	0.558
MOD_CK1_1	169	175	PF00069	0.740
MOD_CK1_1	187	193	PF00069	0.580
MOD_CK1_1	320	326	PF00069	0.700
MOD_CK1_1	423	429	PF00069	0.680
MOD_CK1_1	443	449	PF00069	0.451
MOD_CK2_1	162	168	PF00069	0.585
MOD_CK2_1	207	213	PF00069	0.537
MOD_CK2_1	235	241	PF00069	0.607
MOD_CK2_1	421	427	PF00069	0.709
MOD_CK2_1	62	68	PF00069	0.690
MOD_GlcNHglycan	276	279	PF01048	0.579
MOD_GlcNHglycan	355	358	PF01048	0.702
MOD_GlcNHglycan	366	369	PF01048	0.593
MOD_GlcNHglycan	423	426	PF01048	0.739
MOD_GlcNHglycan	437	440	PF01048	0.646
MOD_GlcNHglycan	442	445	PF01048	0.595
MOD_GSK3_1	162	169	PF00069	0.597
MOD_GSK3_1	183	190	PF00069	0.737
MOD_GSK3_1	263	270	PF00069	0.591
MOD_GSK3_1	313	320	PF00069	0.726
MOD_GSK3_1	360	367	PF00069	0.731
MOD_GSK3_1	416	423	PF00069	0.662
MOD_LATS_1	132	138	PF00433	0.436
MOD_N-GLC_1	317	322	PF02516	0.670
MOD_NEK2_1	136	141	PF00069	0.668
MOD_NEK2_1	182	187	PF00069	0.749
MOD_NEK2_1	202	207	PF00069	0.520
MOD_NEK2_1	263	268	PF00069	0.534
MOD_NEK2_1	274	279	PF00069	0.585
MOD_NEK2_1	442	447	PF00069	0.789
MOD_NEK2_1	448	453	PF00069	0.720
MOD_NEK2_1	55	60	PF00069	0.639
MOD_PIKK_1	134	140	PF00454	0.520
MOD_PIKK_1	169	175	PF00454	0.644
MOD_PIKK_1	184	190	PF00454	0.631
MOD_PIKK_1	297	303	PF00454	0.539
MOD_PIKK_1	3	9	PF00454	0.585
MOD_PIKK_1	443	449	PF00454	0.719
MOD_PK_1	236	242	PF00069	0.691
MOD_PKA_1	223	229	PF00069	0.567
MOD_PKA_1	313	319	PF00069	0.726
MOD_PKA_1	483	489	PF00069	0.712
MOD_PKA_2	127	133	PF00069	0.610
MOD_PKA_2	223	229	PF00069	0.567
MOD_PKA_2	235	241	PF00069	0.569
MOD_PKA_2	292	298	PF00069	0.589
MOD_PKA_2	313	319	PF00069	0.726
MOD_PKA_2	483	489	PF00069	0.624
MOD_PKA_2	78	84	PF00069	0.650
MOD_PKB_1	234	242	PF00069	0.698
MOD_Plk_1	177	183	PF00069	0.607
MOD_Plk_1	317	323	PF00069	0.644
MOD_Plk_4	166	172	PF00069	0.749
MOD_Plk_4	202	208	PF00069	0.561
MOD_Plk_4	416	422	PF00069	0.667
MOD_ProDKin_1	267	273	PF00069	0.612
MOD_ProDKin_1	282	288	PF00069	0.618
MOD_ProDKin_1	414	420	PF00069	0.750
MOD_ProDKin_1	97	103	PF00069	0.515
MOD_SUMO_rev_2	277	286	PF00179	0.643
TRG_DiLeu_BaLyEn_6	467	472	PF01217	0.761
TRG_DiLeu_BaLyEn_6	491	496	PF01217	0.599
TRG_ENDOCYTIC_2	245	248	PF00928	0.561
TRG_ENDOCYTIC_2	468	471	PF00928	0.758
TRG_ENDOCYTIC_2	492	495	PF00928	0.681
TRG_ER_diArg_1	112	115	PF00400	0.553
TRG_ER_diArg_1	222	224	PF00400	0.563
TRG_ER_diArg_1	233	236	PF00400	0.580
TRG_ER_diArg_1	245	247	PF00400	0.446
TRG_ER_diArg_1	312	314	PF00400	0.604
TRG_ER_diArg_1	377	380	PF00400	0.670
TRG_ER_diArg_1	433	435	PF00400	0.677
TRG_ER_diArg_1	482	484	PF00400	0.694
TRG_ER_diArg_1	492	494	PF00400	0.558
TRG_ER_diArg_1	90	92	PF00400	0.760

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5S0	Leptomonas seymouri	41%	98%
A0A1X0P6U1	Trypanosomatidae	24%	100%
A0A3R7MGU2	Trypanosoma rangeli	28%	100%
A0A3S7X9K7	Leishmania donovani	100%	100%
A4HMY2	Leishmania braziliensis	72%	99%
E9AFD9	Leishmania major	93%	100%
E9B6J4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
V5C2W6	Trypanosoma cruzi	26%	100%