LeishMANIAdb
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GN3L_Grn1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
GN3L_Grn1 domain-containing protein
Gene product:
Alb1 - putative
Species:
Leishmania infantum
UniProt:
A4IBH4_LEIIN
TriTrypDb:
LINF_350033900
Length:
151

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 4
GO:0005737 cytoplasm 2 4
GO:0043226 organelle 2 4
GO:0043227 membrane-bounded organelle 3 4
GO:0043229 intracellular organelle 3 4
GO:0043231 intracellular membrane-bounded organelle 4 4
GO:0110165 cellular anatomical entity 1 4

Expansion

Sequence features

A4IBH4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBH4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 106 108 PF00675 0.463
CLV_NRD_NRD_1 111 113 PF00675 0.442
CLV_NRD_NRD_1 17 19 PF00675 0.424
CLV_NRD_NRD_1 23 25 PF00675 0.473
CLV_NRD_NRD_1 5 7 PF00675 0.448
CLV_PCSK_KEX2_1 111 113 PF00082 0.440
CLV_PCSK_KEX2_1 135 137 PF00082 0.391
CLV_PCSK_KEX2_1 14 16 PF00082 0.418
CLV_PCSK_KEX2_1 23 25 PF00082 0.466
CLV_PCSK_KEX2_1 84 86 PF00082 0.610
CLV_PCSK_PC1ET2_1 111 113 PF00082 0.424
CLV_PCSK_PC1ET2_1 135 137 PF00082 0.391
CLV_PCSK_PC1ET2_1 14 16 PF00082 0.418
CLV_PCSK_PC1ET2_1 23 25 PF00082 0.435
CLV_PCSK_PC1ET2_1 84 86 PF00082 0.610
CLV_PCSK_PC7_1 107 113 PF00082 0.440
CLV_PCSK_SKI1_1 103 107 PF00082 0.507
CLV_PCSK_SKI1_1 108 112 PF00082 0.474
CLV_PCSK_SKI1_1 136 140 PF00082 0.438
CLV_PCSK_SKI1_1 6 10 PF00082 0.447
DOC_MAPK_gen_1 134 140 PF00069 0.429
DOC_MAPK_gen_1 84 95 PF00069 0.482
DOC_PP2B_LxvP_1 95 98 PF13499 0.482
DOC_USP7_UBL2_3 111 115 PF12436 0.495
DOC_USP7_UBL2_3 130 134 PF12436 0.396
DOC_USP7_UBL2_3 135 139 PF12436 0.395
DOC_USP7_UBL2_3 19 23 PF12436 0.416
DOC_USP7_UBL2_3 3 7 PF12436 0.468
DOC_USP7_UBL2_3 9 13 PF12436 0.473
LIG_14-3-3_CanoR_1 18 22 PF00244 0.432
LIG_FHA_1 77 83 PF00498 0.505
MOD_GlcNHglycan 69 72 PF01048 0.728
MOD_GSK3_1 34 41 PF00069 0.478
MOD_N-GLC_1 123 128 PF02516 0.402
MOD_PIKK_1 38 44 PF00454 0.629
MOD_PKA_2 17 23 PF00069 0.430
MOD_PKA_2 34 40 PF00069 0.528
MOD_Plk_1 123 129 PF00069 0.404
TRG_NLS_Bipartite_1 84 105 PF00514 0.508
TRG_NLS_MonoExtN_4 3 10 PF00514 0.480
TRG_NLS_MonoExtN_4 98 105 PF00514 0.510
TRG_Pf-PMV_PEXEL_1 6 10 PF00026 0.462

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I1S0 Leptomonas seymouri 77% 100%
A0A0S4JBT2 Bodo saltans 44% 92%
A0A1X0P5F8 Trypanosomatidae 56% 95%
A0A3Q8IIF2 Leishmania donovani 99% 100%
A0A3R7MVM6 Trypanosoma rangeli 55% 100%
A4HMV3 Leishmania braziliensis 80% 100%
C9ZZ68 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 52% 100%
E9AFB0 Leishmania major 93% 100%
E9B6G5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS