MFS domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Major Facilitator Superfamily/Sugar (and other) transporter - putative

Species:

Leishmania infantum

UniProt:

A4IBH1_LEIIN

TriTrypDb:

LINF_350033500

Length:

647

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Show entries

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	14
GO:0110165	cellular anatomical entity	1	14

Previous1Next

Expansion

Sequence features

A4IBH1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBH1

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	14
GO:0022857	transmembrane transporter activity	2	14

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	182	186	PF00656	0.392
CLV_MEL_PAP_1	641	647	PF00089	0.348
CLV_NRD_NRD_1	238	240	PF00675	0.439
CLV_NRD_NRD_1	80	82	PF00675	0.305
CLV_PCSK_FUR_1	236	240	PF00082	0.427
CLV_PCSK_KEX2_1	238	240	PF00082	0.442
CLV_PCSK_PC7_1	234	240	PF00082	0.402
CLV_PCSK_SKI1_1	175	179	PF00082	0.687
CLV_PCSK_SKI1_1	436	440	PF00082	0.410
CLV_PCSK_SKI1_1	505	509	PF00082	0.361

Previous1 2 3 4 5…22Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMM8	Leptomonas seymouri	31%	98%
A0A0S4KJ45	Bodo saltans	28%	100%
A0A3Q8II42	Leishmania donovani	99%	100%
A0A3Q8IPN7	Leishmania donovani	31%	92%
A4HMU7	Leishmania braziliensis	30%	100%
A4HMU9	Leishmania braziliensis	71%	100%
A4IBH0	Leishmania infantum	31%	92%
E8NHI2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	92%
E9AFA5	Leishmania major	31%	92%
E9AFA6	Leishmania major	88%	100%

Previous1 2Next