Putative RNA binding protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Double RNA binding domain protein 9

Species:

Leishmania infantum

UniProt:

A4IBG4_LEIIN

TriTrypDb:

LINF_350030700

Length:

197

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBG4

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	125	129	PF00656	0.504
CLV_NRD_NRD_1	102	104	PF00675	0.455
CLV_NRD_NRD_1	106	108	PF00675	0.455
CLV_NRD_NRD_1	119	121	PF00675	0.499
CLV_NRD_NRD_1	162	164	PF00675	0.475
CLV_NRD_NRD_1	189	191	PF00675	0.464
CLV_PCSK_FUR_1	103	107	PF00082	0.454
CLV_PCSK_FUR_1	190	194	PF00082	0.466
CLV_PCSK_KEX2_1	102	104	PF00082	0.455
CLV_PCSK_KEX2_1	105	107	PF00082	0.457
CLV_PCSK_KEX2_1	121	123	PF00082	0.506
CLV_PCSK_KEX2_1	162	164	PF00082	0.475
CLV_PCSK_KEX2_1	189	191	PF00082	0.464
CLV_PCSK_KEX2_1	192	194	PF00082	0.466
CLV_PCSK_KEX2_1	41	43	PF00082	0.199
CLV_PCSK_PC1ET2_1	105	107	PF00082	0.457
CLV_PCSK_PC1ET2_1	121	123	PF00082	0.506
CLV_PCSK_PC1ET2_1	189	191	PF00082	0.464
CLV_PCSK_PC1ET2_1	192	194	PF00082	0.466
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.199
CLV_PCSK_PC7_1	102	108	PF00082	0.454
CLV_PCSK_PC7_1	185	191	PF00082	0.455
CLV_PCSK_SKI1_1	93	97	PF00082	0.461
DEG_Nend_UBRbox_2	1	3	PF02207	0.479
DOC_ANK_TNKS_1	169	176	PF00023	0.459
DOC_PP1_RVXF_1	174	180	PF00149	0.463
DOC_USP7_MATH_1	10	14	PF00917	0.292
DOC_USP7_MATH_1	98	102	PF00917	0.464
DOC_USP7_UBL2_3	176	180	PF12436	0.465
DOC_USP7_UBL2_3	96	100	PF12436	0.468
DOC_WW_Pin1_4	133	138	PF00397	0.493
LIG_BIR_III_4	128	132	PF00653	0.501
LIG_deltaCOP1_diTrp_1	25	32	PF00928	0.400
LIG_FHA_2	145	151	PF00498	0.437
LIG_FHA_2	21	27	PF00498	0.400
LIG_FHA_2	72	78	PF00498	0.400
LIG_Integrin_isoDGR_2	80	82	PF01839	0.199
LIG_Integrin_RGD_1	75	77	PF01839	0.199
LIG_LIR_Gen_1	136	145	PF02991	0.479
LIG_LIR_Gen_1	26	37	PF02991	0.400
LIG_LIR_Nem_3	136	142	PF02991	0.485
LIG_LIR_Nem_3	153	157	PF02991	0.461
LIG_LIR_Nem_3	26	32	PF02991	0.400
LIG_PTB_Apo_2	15	22	PF02174	0.400
LIG_PTB_Phospho_1	15	21	PF10480	0.400
LIG_SH2_STAT5	59	62	PF00017	0.400
LIG_SH3_2	184	189	PF14604	0.449
LIG_SH3_3	139	145	PF00018	0.477
LIG_SH3_3	178	184	PF00018	0.448
LIG_TRAF2_1	23	26	PF00917	0.400
LIG_WRC_WIRS_1	28	33	PF05994	0.400
MOD_CK1_1	133	139	PF00069	0.495
MOD_CK2_1	20	26	PF00069	0.400
MOD_CK2_1	98	104	PF00069	0.460
MOD_GlcNHglycan	124	127	PF01048	0.506
MOD_GSK3_1	133	140	PF00069	0.492
MOD_GSK3_1	146	153	PF00069	0.440
MOD_N-GLC_1	21	26	PF02516	0.199
MOD_N-GLC_1	89	94	PF02516	0.414
MOD_NEK2_1	63	68	PF00069	0.400
MOD_NEK2_2	10	15	PF00069	0.294
MOD_PKA_1	105	111	PF00069	0.461
MOD_PKA_1	120	126	PF00069	0.506
MOD_PKA_2	105	111	PF00069	0.461
MOD_PKA_2	48	54	PF00069	0.400
MOD_PKB_1	120	128	PF00069	0.506
MOD_Plk_1	10	16	PF00069	0.290
MOD_Plk_1	137	143	PF00069	0.484
MOD_Plk_4	10	16	PF00069	0.290
MOD_ProDKin_1	133	139	PF00069	0.495
MOD_SUMO_rev_2	118	123	PF00179	0.504
MOD_SUMO_rev_2	168	177	PF00179	0.460
MOD_SUMO_rev_2	34	43	PF00179	0.400
MOD_SUMO_rev_2	48	57	PF00179	0.400
MOD_SUMO_rev_2	92	98	PF00179	0.459
TRG_DiLeu_BaEn_2	10	16	PF01217	0.290
TRG_ENDOCYTIC_2	139	142	PF00928	0.486
TRG_ENDOCYTIC_2	59	62	PF00928	0.400
TRG_ER_diArg_1	161	163	PF00400	0.474
TRG_ER_diArg_1	42	45	PF00400	0.400
TRG_NLS_Bipartite_1	105	125	PF00514	0.490
TRG_NLS_MonoCore_2	142	147	PF00514	0.460
TRG_NLS_MonoCore_2	188	193	PF00514	0.464
TRG_NLS_MonoExtC_3	142	148	PF00514	0.459
TRG_NLS_MonoExtC_3	188	193	PF00514	0.464
TRG_NLS_MonoExtN_4	120	125	PF00514	0.504
TRG_NLS_MonoExtN_4	187	194	PF00514	0.460
TRG_Pf-PMV_PEXEL_1	170	174	PF00026	0.457

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A6NDY0	HUMAN	33%	71%
B0BN49	RAT	32%	60%
B0BNE4	RAT	29%	73%
O13741	SCHPO	35%	45%
O13829	SCHPO	32%	75%
O13845	SCHPO	38%	33%
O14327	SCHPO	39%	100%
O14369	SCHPO	38%	51%
O89086	MOUSE	35%	100%
P10979	MAIZE	34%	100%
P27476	YEAST	32%	48%
P28644	SPIOL	35%	85%
P33240	HUMAN	39%	34%
P40561	YEAST	35%	79%
P41891	SCHPO	36%	39%
P42696	HUMAN	41%	46%
P53883	YEAST	28%	49%
P60824	MOUSE	29%	100%
P60825	RAT	29%	100%
P60826	CRIGR	29%	100%
P98179	HUMAN	35%	100%
Q03251	ARATH	35%	100%
Q03878	DAUCA	35%	100%
Q04836	ARATH	34%	60%
Q05966	BRANA	34%	100%
Q08208	YEAST	39%	43%
Q09100	SCHPO	35%	53%
Q09301	CAEEL	32%	100%
Q09511	CAEEL	35%	100%
Q10B98	ORYSJ	33%	63%
Q14011	HUMAN	29%	100%
Q15056	HUMAN	40%	79%
Q1JPH6	BOVIN	40%	86%
Q1PEP5	ARATH	36%	31%
Q28165	BOVIN	32%	64%
Q28IQ9	XENTR	33%	100%
Q44554	NOSS1	45%	100%
Q44556	NOSS1	43%	100%
Q44560	NOSS1	40%	100%
Q54ZS8	DICDI	35%	89%
Q57014	SYNY3	44%	100%
Q5AHI7	CANAL	38%	43%
Q5M9F1	RAT	38%	46%
Q5RBR8	PONAB	40%	86%
Q5RDA3	PONAB	39%	34%
Q5RF83	PONAB	29%	100%
Q5XI72	RAT	40%	79%
Q6BTS9	DEBHA	26%	43%
Q6C2Q7	YARLI	35%	39%
Q6CKV6	KLULA	33%	43%
Q6FUS6	CANGA	31%	50%
Q6NVP7	XENTR	34%	67%
Q6Z1C0	ORYSJ	36%	34%
Q75BJ7	ASHGO	34%	46%
Q7KNF2	DROME	29%	88%
Q7ZXB8	XENLA	36%	67%
Q86U42	HUMAN	32%	64%
Q8BIQ5	MOUSE	39%	34%
Q8C5L7	MOUSE	37%	45%
Q8C7E9	MOUSE	39%	31%
Q8CCS6	MOUSE	32%	65%
Q8HXM1	BOVIN	39%	34%
Q8R0F5	MOUSE	33%	60%
Q925G0	RAT	36%	100%
Q93VI4	ARATH	39%	87%
Q9C909	ARATH	31%	68%
Q9DDY9	XENLA	36%	67%
Q9DED4	XENLA	31%	100%
Q9FJN9	ARATH	41%	90%
Q9FMG4	ARATH	31%	65%
Q9FNR1	ARATH	35%	64%
Q9FVQ1	ARATH	39%	35%
Q9H0L4	HUMAN	39%	32%
Q9LHP2	ARATH	34%	75%
Q9LIS2	ARATH	35%	100%
Q9LX90	ARATH	41%	91%
Q9M9G6	ARATH	38%	43%
Q9PTX2	LITCT	30%	100%
Q9SEU4	ARATH	35%	69%
Q9SIX3	ARATH	38%	100%
Q9SVM8	ARATH	35%	100%
Q9WUK2	MOUSE	40%	79%
Q9WX37	NOSS1	40%	100%
Q9WX39	NOSS1	44%	100%
Q9Y388	HUMAN	32%	61%
W8E7I1	CAPHI	35%	100%