Pecanex_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IBF9_LEIIN

TriTrypDb:

LINF_350030200

Length:

555

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBF9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	451	455	PF00656	0.811
CLV_NRD_NRD_1	211	213	PF00675	0.656
CLV_NRD_NRD_1	433	435	PF00675	0.734
CLV_NRD_NRD_1	99	101	PF00675	0.691
CLV_PCSK_KEX2_1	213	215	PF00082	0.643
CLV_PCSK_KEX2_1	433	435	PF00082	0.703
CLV_PCSK_KEX2_1	443	445	PF00082	0.721
CLV_PCSK_KEX2_1	470	472	PF00082	0.543
CLV_PCSK_KEX2_1	99	101	PF00082	0.724
CLV_PCSK_PC1ET2_1	213	215	PF00082	0.697
CLV_PCSK_PC1ET2_1	443	445	PF00082	0.753
CLV_PCSK_PC1ET2_1	470	472	PF00082	0.543
CLV_PCSK_SKI1_1	128	132	PF00082	0.553
DEG_APCC_DBOX_1	365	373	PF00400	0.547
DOC_CKS1_1	48	53	PF01111	0.647
DOC_CYCLIN_yCln2_LP_2	174	180	PF00134	0.514
DOC_CYCLIN_yCln2_LP_2	310	316	PF00134	0.545
DOC_CYCLIN_yCln2_LP_2	42	45	PF00134	0.671
DOC_MAPK_gen_1	433	441	PF00069	0.593
DOC_MAPK_gen_1	99	107	PF00069	0.549
DOC_PP2B_LxvP_1	42	45	PF13499	0.641
DOC_PP4_FxxP_1	287	290	PF00568	0.634
DOC_USP7_MATH_1	130	134	PF00917	0.597
DOC_USP7_MATH_1	156	160	PF00917	0.482
DOC_USP7_MATH_1	181	185	PF00917	0.741
DOC_USP7_MATH_1	195	199	PF00917	0.692
DOC_USP7_MATH_1	301	305	PF00917	0.656
DOC_USP7_MATH_1	356	360	PF00917	0.590
DOC_USP7_MATH_1	452	456	PF00917	0.782
DOC_USP7_MATH_1	530	534	PF00917	0.602
DOC_USP7_MATH_1	540	544	PF00917	0.706
DOC_USP7_MATH_1	66	70	PF00917	0.650
DOC_USP7_MATH_1	86	90	PF00917	0.378
DOC_WW_Pin1_4	199	204	PF00397	0.771
DOC_WW_Pin1_4	227	232	PF00397	0.651
DOC_WW_Pin1_4	295	300	PF00397	0.617
DOC_WW_Pin1_4	323	328	PF00397	0.585
DOC_WW_Pin1_4	349	354	PF00397	0.436
DOC_WW_Pin1_4	391	396	PF00397	0.592
DOC_WW_Pin1_4	47	52	PF00397	0.586
LIG_14-3-3_CanoR_1	273	279	PF00244	0.528
LIG_14-3-3_CanoR_1	28	33	PF00244	0.586
LIG_14-3-3_CanoR_1	281	291	PF00244	0.596
LIG_14-3-3_CanoR_1	336	346	PF00244	0.486
LIG_Actin_WH2_2	473	490	PF00022	0.332
LIG_APCC_ABBA_1	36	41	PF00400	0.481
LIG_BRCT_BRCA1_1	158	162	PF00533	0.429
LIG_BRCT_BRCA1_1	197	201	PF00533	0.659
LIG_BRCT_BRCA1_1	245	249	PF00533	0.559
LIG_CSL_BTD_1	226	229	PF09270	0.626
LIG_deltaCOP1_diTrp_1	225	234	PF00928	0.621
LIG_eIF4E_1	37	43	PF01652	0.486
LIG_EVH1_1	43	47	PF00568	0.554
LIG_FHA_1	106	112	PF00498	0.558
LIG_FHA_1	13	19	PF00498	0.535
LIG_FHA_1	283	289	PF00498	0.643
LIG_FHA_1	291	297	PF00498	0.616
LIG_FHA_1	474	480	PF00498	0.461
LIG_FHA_1	48	54	PF00498	0.551
LIG_FHA_1	537	543	PF00498	0.623
LIG_FHA_1	74	80	PF00498	0.663
LIG_FHA_2	122	128	PF00498	0.657
LIG_FHA_2	234	240	PF00498	0.552
LIG_FHA_2	264	270	PF00498	0.484
LIG_FHA_2	28	34	PF00498	0.546
LIG_FHA_2	403	409	PF00498	0.529
LIG_FHA_2	93	99	PF00498	0.588
LIG_LIR_Apic_2	269	274	PF02991	0.543
LIG_LIR_Apic_2	285	290	PF02991	0.614
LIG_LIR_Apic_2	29	35	PF02991	0.521
LIG_LIR_Gen_1	159	167	PF02991	0.424
LIG_LIR_Nem_3	159	165	PF02991	0.427
LIG_LIR_Nem_3	329	335	PF02991	0.637
LIG_LIR_Nem_3	340	346	PF02991	0.508
LIG_MYND_1	40	44	PF01753	0.514
LIG_PCNA_PIPBox_1	515	524	PF02747	0.468
LIG_Pex14_1	478	482	PF04695	0.385
LIG_SH2_CRK	344	348	PF00017	0.451
LIG_SH2_NCK_1	423	427	PF00017	0.500
LIG_SH2_SRC	32	35	PF00017	0.512
LIG_SH2_SRC	423	426	PF00017	0.488
LIG_SH2_STAP1	344	348	PF00017	0.451
LIG_SH2_STAP1	423	427	PF00017	0.609
LIG_SH2_STAP1	475	479	PF00017	0.495
LIG_SH2_STAT5	331	334	PF00017	0.578
LIG_SH2_STAT5	37	40	PF00017	0.476
LIG_SH2_STAT5	375	378	PF00017	0.507
LIG_SH2_STAT5	403	406	PF00017	0.520
LIG_SH2_STAT5	475	478	PF00017	0.498
LIG_SH3_3	202	208	PF00018	0.518
LIG_SH3_3	223	229	PF00018	0.585
LIG_SH3_3	285	291	PF00018	0.704
LIG_SH3_3	293	299	PF00018	0.697
LIG_SH3_3	41	47	PF00018	0.542
LIG_SH3_3	415	421	PF00018	0.491
LIG_SH3_3	429	435	PF00018	0.706
LIG_SH3_3	48	54	PF00018	0.572
LIG_SH3_5	327	331	PF00018	0.538
LIG_Sin3_3	343	350	PF02671	0.335
LIG_SUMO_SIM_anti_2	506	513	PF11976	0.502
LIG_SUMO_SIM_par_1	103	109	PF11976	0.568
LIG_SUMO_SIM_par_1	506	513	PF11976	0.502
LIG_TRAF2_1	150	153	PF00917	0.603
LIG_TRAF2_1	368	371	PF00917	0.385
LIG_WW_1	34	37	PF00397	0.464
LIG_WW_2	51	54	PF00397	0.642
MOD_CK1_1	243	249	PF00069	0.580
MOD_CK1_1	27	33	PF00069	0.698
MOD_CK1_1	326	332	PF00069	0.581
MOD_CK1_1	349	355	PF00069	0.437
MOD_CK1_1	533	539	PF00069	0.638
MOD_CK1_1	541	547	PF00069	0.756
MOD_CK2_1	121	127	PF00069	0.571
MOD_CK2_1	147	153	PF00069	0.590
MOD_CK2_1	181	187	PF00069	0.594
MOD_CK2_1	188	194	PF00069	0.714
MOD_CK2_1	233	239	PF00069	0.666
MOD_CK2_1	263	269	PF00069	0.617
MOD_CK2_1	27	33	PF00069	0.551
MOD_CK2_1	402	408	PF00069	0.527
MOD_CK2_1	92	98	PF00069	0.588
MOD_Cter_Amidation	441	444	PF01082	0.631
MOD_GlcNHglycan	132	135	PF01048	0.502
MOD_GlcNHglycan	183	186	PF01048	0.687
MOD_GlcNHglycan	197	200	PF01048	0.695
MOD_GlcNHglycan	244	248	PF01048	0.635
MOD_GlcNHglycan	348	351	PF01048	0.436
MOD_GlcNHglycan	354	357	PF01048	0.677
MOD_GlcNHglycan	358	361	PF01048	0.670
MOD_GlcNHglycan	379	382	PF01048	0.466
MOD_GlcNHglycan	522	525	PF01048	0.568
MOD_GlcNHglycan	88	91	PF01048	0.580
MOD_GSK3_1	195	202	PF00069	0.714
MOD_GSK3_1	208	215	PF00069	0.719
MOD_GSK3_1	24	31	PF00069	0.691
MOD_GSK3_1	290	297	PF00069	0.604
MOD_GSK3_1	319	326	PF00069	0.692
MOD_GSK3_1	352	359	PF00069	0.706
MOD_GSK3_1	536	543	PF00069	0.732
MOD_N-GLC_1	294	299	PF02516	0.543
MOD_NEK2_1	121	126	PF00069	0.497
MOD_NEK2_1	24	29	PF00069	0.613
MOD_NEK2_1	263	268	PF00069	0.473
MOD_NEK2_2	331	336	PF00069	0.444
MOD_PIKK_1	542	548	PF00454	0.698
MOD_PIKK_1	73	79	PF00454	0.575
MOD_PKA_1	212	218	PF00069	0.686
MOD_PKA_2	27	33	PF00069	0.586
MOD_PKA_2	377	383	PF00069	0.489
MOD_Plk_1	121	127	PF00069	0.555
MOD_Plk_1	370	376	PF00069	0.493
MOD_Plk_1	533	539	PF00069	0.705
MOD_Plk_1	73	79	PF00069	0.510
MOD_Plk_2-3	450	456	PF00069	0.669
MOD_Plk_4	106	112	PF00069	0.439
MOD_Plk_4	121	127	PF00069	0.430
MOD_Plk_4	371	377	PF00069	0.559
MOD_Plk_4	473	479	PF00069	0.464
MOD_ProDKin_1	199	205	PF00069	0.768
MOD_ProDKin_1	227	233	PF00069	0.652
MOD_ProDKin_1	295	301	PF00069	0.612
MOD_ProDKin_1	323	329	PF00069	0.581
MOD_ProDKin_1	349	355	PF00069	0.452
MOD_ProDKin_1	391	397	PF00069	0.587
MOD_ProDKin_1	47	53	PF00069	0.591
MOD_SUMO_for_1	547	550	PF00179	0.587
MOD_SUMO_rev_2	184	191	PF00179	0.624
TRG_DiLeu_BaEn_3	152	158	PF01217	0.553
TRG_DiLeu_BaLyEn_6	112	117	PF01217	0.576
TRG_ENDOCYTIC_2	344	347	PF00928	0.452
TRG_ER_diArg_1	432	434	PF00400	0.593
TRG_ER_diArg_1	99	101	PF00400	0.630
TRG_NLS_MonoExtC_3	211	216	PF00514	0.746
TRG_NLS_MonoExtN_4	209	216	PF00514	0.746

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEG0	Leptomonas seymouri	59%	100%
A0A1X0P5K7	Trypanosomatidae	34%	100%
A0A3Q8IJ29	Leishmania donovani	99%	100%
A0A3R7KY71	Trypanosoma rangeli	37%	100%
A4HMS3	Leishmania braziliensis	80%	100%
C9ZZA5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
E9AF73	Leishmania major	94%	100%
E9B6C9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
V5DK90	Trypanosoma cruzi	37%	100%