Cilia- and flagella-associated protein 157

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IBE3_LEIIN

TriTrypDb:

LINF_350032800

Length:

377

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBE3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBE3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	273	277	PF00656	0.526
CLV_C14_Caspase3-7	279	283	PF00656	0.521
CLV_C14_Caspase3-7	51	55	PF00656	0.619
CLV_NRD_NRD_1	126	128	PF00675	0.498
CLV_NRD_NRD_1	266	268	PF00675	0.673
CLV_NRD_NRD_1	355	357	PF00675	0.683
CLV_NRD_NRD_1	69	71	PF00675	0.612
CLV_NRD_NRD_1	72	74	PF00675	0.647
CLV_PCSK_FUR_1	70	74	PF00082	0.548
CLV_PCSK_KEX2_1	152	154	PF00082	0.712
CLV_PCSK_KEX2_1	185	187	PF00082	0.571
CLV_PCSK_KEX2_1	266	268	PF00082	0.673
CLV_PCSK_KEX2_1	355	357	PF00082	0.683
CLV_PCSK_KEX2_1	71	73	PF00082	0.645
CLV_PCSK_PC1ET2_1	152	154	PF00082	0.712
CLV_PCSK_PC1ET2_1	185	187	PF00082	0.571
CLV_PCSK_PC1ET2_1	71	73	PF00082	0.610
CLV_PCSK_SKI1_1	167	171	PF00082	0.693
CLV_PCSK_SKI1_1	355	359	PF00082	0.689
CLV_PCSK_SKI1_1	80	84	PF00082	0.679
CLV_Separin_Metazoa	339	343	PF03568	0.683
DEG_APCC_DBOX_1	268	276	PF00400	0.692
DEG_APCC_DBOX_1	79	87	PF00400	0.732
DEG_Nend_Nbox_1	1	3	PF02207	0.529
DOC_CKS1_1	106	111	PF01111	0.690
DOC_CYCLIN_RxL_1	77	84	PF00134	0.708
DOC_MAPK_FxFP_2	300	303	PF00069	0.693
DOC_MAPK_gen_1	266	274	PF00069	0.685
DOC_MAPK_gen_1	355	361	PF00069	0.700
DOC_PP4_FxxP_1	300	303	PF00568	0.693
DOC_USP7_MATH_1	224	228	PF00917	0.687
DOC_USP7_MATH_1	287	291	PF00917	0.642
DOC_USP7_MATH_1	292	296	PF00917	0.583
DOC_USP7_MATH_1	373	377	PF00917	0.713
DOC_USP7_MATH_1	48	52	PF00917	0.640
DOC_WW_Pin1_4	105	110	PF00397	0.770
LIG_BIR_III_4	282	286	PF00653	0.668
LIG_BIR_III_4	54	58	PF00653	0.721
LIG_eIF4E_1	320	326	PF01652	0.673
LIG_FHA_1	193	199	PF00498	0.511
LIG_FHA_1	4	10	PF00498	0.829
LIG_FHA_2	175	181	PF00498	0.400
LIG_LIR_Nem_3	301	307	PF02991	0.496
LIG_NRBOX	139	145	PF00104	0.407
LIG_NRBOX	82	88	PF00104	0.741
LIG_PCNA_yPIPBox_3	27	38	PF02747	0.477
LIG_SH2_CRK	304	308	PF00017	0.487
LIG_SH2_STAP1	194	198	PF00017	0.663
LIG_SH2_STAT3	320	323	PF00017	0.669
LIG_SH2_STAT5	194	197	PF00017	0.449
LIG_SH3_3	12	18	PF00018	0.582
LIG_SH3_3	87	93	PF00018	0.672
LIG_SUMO_SIM_par_1	36	42	PF11976	0.552
LIG_TRAF2_1	114	117	PF00917	0.738
LIG_TRAF2_1	197	200	PF00917	0.656
LIG_TRAF2_1	227	230	PF00917	0.681
LIG_TRAF2_1	30	33	PF00917	0.652
LIG_UBA3_1	346	351	PF00899	0.662
MOD_CK1_1	25	31	PF00069	0.523
MOD_CK2_1	104	110	PF00069	0.827
MOD_CK2_1	142	148	PF00069	0.691
MOD_CK2_1	174	180	PF00069	0.480
MOD_CK2_1	224	230	PF00069	0.687
MOD_GlcNHglycan	160	164	PF01048	0.686
MOD_GlcNHglycan	289	292	PF01048	0.812
MOD_GlcNHglycan	50	53	PF01048	0.629
MOD_GSK3_1	127	134	PF00069	0.585
MOD_GSK3_1	369	376	PF00069	0.820
MOD_GSK3_1	88	95	PF00069	0.804
MOD_N-GLC_1	25	30	PF02516	0.702
MOD_N-GLC_1	250	255	PF02516	0.495
MOD_N-GLC_1	332	337	PF02516	0.689
MOD_NEK2_1	319	324	PF00069	0.669
MOD_PIKK_1	142	148	PF00454	0.399
MOD_PIKK_1	192	198	PF00454	0.535
MOD_PIKK_1	206	212	PF00454	0.550
MOD_PIKK_1	314	320	PF00454	0.680
MOD_PKA_1	127	133	PF00069	0.587
MOD_PKA_2	134	140	PF00069	0.640
MOD_Plk_1	250	256	PF00069	0.498
MOD_Plk_2-3	276	282	PF00069	0.726
MOD_ProDKin_1	105	111	PF00069	0.765
MOD_SUMO_rev_2	328	337	PF00179	0.400
MOD_SUMO_rev_2	51	58	PF00179	0.436
TRG_DiLeu_BaEn_1	33	38	PF01217	0.739
TRG_DiLeu_BaLyEn_6	82	87	PF01217	0.736
TRG_ENDOCYTIC_2	304	307	PF00928	0.501
TRG_ER_diArg_1	265	267	PF00400	0.668
TRG_ER_diArg_1	268	271	PF00400	0.631
TRG_ER_diArg_1	354	356	PF00400	0.679
TRG_ER_diArg_1	70	73	PF00400	0.633
TRG_NES_CRM1_1	348	360	PF08389	0.674
TRG_Pf-PMV_PEXEL_1	127	131	PF00026	0.588
TRG_Pf-PMV_PEXEL_1	138	142	PF00026	0.461
TRG_Pf-PMV_PEXEL_1	256	260	PF00026	0.667
TRG_Pf-PMV_PEXEL_1	266	270	PF00026	0.502
TRG_Pf-PMV_PEXEL_1	64	68	PF00026	0.716
TRG_Pf-PMV_PEXEL_1	85	89	PF00026	0.758

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AF99	Leishmania major	87%	100%
E9B6F4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%