Protein kinase domain-containing protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IBA9_LEIIN

TriTrypDb:

LINF_350026200

Length:

664

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Phosphorylation

Amastigote: 376, 417, 418, 572, 650
Promastigote/Amastigote: 345, 348, 461, 465

Expansion

Sequence features

A4IBA9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBA9

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	364	368	PF00656	0.703
CLV_NRD_NRD_1	341	343	PF00675	0.628
CLV_NRD_NRD_1	361	363	PF00675	0.664
CLV_NRD_NRD_1	386	388	PF00675	0.668
CLV_PCSK_KEX2_1	360	362	PF00082	0.655
CLV_PCSK_KEX2_1	386	388	PF00082	0.668
CLV_PCSK_KEX2_1	420	422	PF00082	0.648
CLV_PCSK_PC1ET2_1	420	422	PF00082	0.648
CLV_PCSK_SKI1_1	503	507	PF00082	0.457
CLV_PCSK_SKI1_1	543	547	PF00082	0.468

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVJ7	Leptomonas seymouri	51%	87%
A0A3R7K4W1	Trypanosoma rangeli	26%	82%
A0A3S7X976	Leishmania donovani	100%	100%
A4HMN2	Leishmania braziliensis	76%	100%
E9AF34	Leishmania major	89%	95%
E9B689	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%

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