LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IBA8_LEIIN
TriTrypDb:
LINF_350026100
Length:
723

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IBA8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IBA8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 104 108 PF00656 0.564
CLV_C14_Caspase3-7 717 721 PF00656 0.606
CLV_NRD_NRD_1 164 166 PF00675 0.746
CLV_NRD_NRD_1 171 173 PF00675 0.778
CLV_NRD_NRD_1 284 286 PF00675 0.595
CLV_NRD_NRD_1 329 331 PF00675 0.583
CLV_NRD_NRD_1 351 353 PF00675 0.605
CLV_NRD_NRD_1 380 382 PF00675 0.585
CLV_NRD_NRD_1 451 453 PF00675 0.507
CLV_NRD_NRD_1 590 592 PF00675 0.693
CLV_PCSK_FUR_1 169 173 PF00082 0.782
CLV_PCSK_FUR_1 210 214 PF00082 0.777
CLV_PCSK_FUR_1 282 286 PF00082 0.628
CLV_PCSK_KEX2_1 169 171 PF00082 0.804
CLV_PCSK_KEX2_1 179 181 PF00082 0.749
CLV_PCSK_KEX2_1 212 214 PF00082 0.776
CLV_PCSK_KEX2_1 284 286 PF00082 0.609
CLV_PCSK_KEX2_1 329 331 PF00082 0.586
CLV_PCSK_KEX2_1 351 353 PF00082 0.605
CLV_PCSK_KEX2_1 380 382 PF00082 0.585
CLV_PCSK_KEX2_1 451 453 PF00082 0.528
CLV_PCSK_KEX2_1 590 592 PF00082 0.693
CLV_PCSK_PC1ET2_1 179 181 PF00082 0.807
CLV_PCSK_PC1ET2_1 212 214 PF00082 0.776
CLV_PCSK_PC7_1 165 171 PF00082 0.778
CLV_PCSK_SKI1_1 179 183 PF00082 0.839
CLV_PCSK_SKI1_1 339 343 PF00082 0.566
CLV_PCSK_SKI1_1 381 385 PF00082 0.528
CLV_PCSK_SKI1_1 428 432 PF00082 0.637
CLV_PCSK_SKI1_1 435 439 PF00082 0.500
CLV_PCSK_SKI1_1 46 50 PF00082 0.600
CLV_PCSK_SKI1_1 94 98 PF00082 0.696
DEG_APCC_DBOX_1 12 20 PF00400 0.577
DEG_APCC_DBOX_1 265 273 PF00400 0.557
DEG_SCF_FBW7_1 132 139 PF00400 0.600
DEG_SPOP_SBC_1 181 185 PF00917 0.841
DEG_SPOP_SBC_1 630 634 PF00917 0.677
DEG_SPOP_SBC_1 700 704 PF00917 0.677
DOC_CYCLIN_yCln2_LP_2 642 648 PF00134 0.754
DOC_MAPK_gen_1 282 290 PF00069 0.580
DOC_MAPK_gen_1 292 299 PF00069 0.570
DOC_MAPK_gen_1 46 55 PF00069 0.670
DOC_MAPK_gen_1 474 483 PF00069 0.509
DOC_MAPK_gen_1 605 613 PF00069 0.625
DOC_MAPK_MEF2A_6 49 57 PF00069 0.675
DOC_PP1_RVXF_1 337 344 PF00149 0.571
DOC_PP1_RVXF_1 458 465 PF00149 0.476
DOC_PP2B_PxIxI_1 220 226 PF00149 0.607
DOC_PP4_FxxP_1 311 314 PF00568 0.614
DOC_PP4_FxxP_1 456 459 PF00568 0.473
DOC_USP7_MATH_1 181 185 PF00917 0.841
DOC_USP7_MATH_1 234 238 PF00917 0.793
DOC_USP7_MATH_1 403 407 PF00917 0.690
DOC_USP7_MATH_1 433 437 PF00917 0.632
DOC_USP7_MATH_1 548 552 PF00917 0.583
DOC_USP7_MATH_1 582 586 PF00917 0.724
DOC_USP7_MATH_1 630 634 PF00917 0.647
DOC_USP7_MATH_1 637 641 PF00917 0.697
DOC_USP7_MATH_1 699 703 PF00917 0.758
DOC_USP7_UBL2_3 59 63 PF12436 0.596
DOC_WW_Pin1_4 132 137 PF00397 0.741
DOC_WW_Pin1_4 416 421 PF00397 0.729
DOC_WW_Pin1_4 512 517 PF00397 0.450
DOC_WW_Pin1_4 649 654 PF00397 0.777
DOC_WW_Pin1_4 680 685 PF00397 0.763
DOC_WW_Pin1_4 703 708 PF00397 0.725
DOC_WW_Pin1_4 711 716 PF00397 0.650
LIG_14-3-3_CanoR_1 13 22 PF00244 0.512
LIG_14-3-3_CanoR_1 180 190 PF00244 0.797
LIG_14-3-3_CanoR_1 224 230 PF00244 0.797
LIG_14-3-3_CanoR_1 266 270 PF00244 0.680
LIG_14-3-3_CanoR_1 415 419 PF00244 0.644
LIG_14-3-3_CanoR_1 428 433 PF00244 0.490
LIG_14-3-3_CanoR_1 435 441 PF00244 0.422
LIG_14-3-3_CanoR_1 605 611 PF00244 0.649
LIG_APCC_ABBA_1 288 293 PF00400 0.646
LIG_APCC_ABBA_1 53 58 PF00400 0.568
LIG_BIR_II_1 1 5 PF00653 0.584
LIG_BIR_III_3 1 5 PF00653 0.622
LIG_BRCT_BRCA1_1 307 311 PF00533 0.597
LIG_BRCT_BRCA1_1 460 464 PF00533 0.526
LIG_BRCT_BRCA1_1 631 635 PF00533 0.754
LIG_BRCT_BRCA1_1 639 643 PF00533 0.698
LIG_Clathr_ClatBox_1 296 300 PF01394 0.623
LIG_FHA_1 247 253 PF00498 0.795
LIG_FHA_1 333 339 PF00498 0.529
LIG_FHA_1 587 593 PF00498 0.751
LIG_FHA_1 594 600 PF00498 0.788
LIG_FHA_1 676 682 PF00498 0.737
LIG_FHA_2 31 37 PF00498 0.584
LIG_FHA_2 429 435 PF00498 0.590
LIG_FHA_2 437 443 PF00498 0.567
LIG_FHA_2 468 474 PF00498 0.506
LIG_Integrin_RGD_1 241 243 PF01839 0.761
LIG_LIR_Apic_2 308 314 PF02991 0.606
LIG_LIR_Gen_1 305 315 PF02991 0.606
LIG_LIR_Gen_1 84 93 PF02991 0.633
LIG_LIR_Nem_3 305 310 PF02991 0.599
LIG_LIR_Nem_3 575 579 PF02991 0.750
LIG_LIR_Nem_3 612 617 PF02991 0.658
LIG_LIR_Nem_3 80 86 PF02991 0.646
LIG_MLH1_MIPbox_1 307 311 PF16413 0.597
LIG_MYND_1 649 653 PF01753 0.834
LIG_NRBOX 491 497 PF00104 0.592
LIG_PCNA_PIPBox_1 312 321 PF02747 0.586
LIG_PDZ_Class_1 718 723 PF00595 0.757
LIG_Pex14_2 22 26 PF04695 0.529
LIG_Pex14_2 307 311 PF04695 0.597
LIG_Pex14_2 464 468 PF04695 0.465
LIG_Rb_pABgroove_1 608 616 PF01858 0.662
LIG_REV1ctd_RIR_1 308 313 PF16727 0.604
LIG_SH2_CRK 503 507 PF00017 0.507
LIG_SH2_NCK_1 324 328 PF00017 0.600
LIG_SH2_NCK_1 86 90 PF00017 0.644
LIG_SH2_PTP2 576 579 PF00017 0.701
LIG_SH2_SRC 576 579 PF00017 0.701
LIG_SH2_STAT5 147 150 PF00017 0.578
LIG_SH2_STAT5 318 321 PF00017 0.546
LIG_SH2_STAT5 324 327 PF00017 0.560
LIG_SH2_STAT5 576 579 PF00017 0.701
LIG_SH2_STAT5 64 67 PF00017 0.531
LIG_SH2_STAT5 7 10 PF00017 0.645
LIG_SH3_3 251 257 PF00018 0.660
LIG_SH3_3 576 582 PF00018 0.803
LIG_SH3_3 709 715 PF00018 0.751
LIG_SH3_CIN85_PxpxPR_1 645 650 PF14604 0.619
LIG_SUMO_SIM_anti_2 251 256 PF11976 0.616
LIG_SUMO_SIM_anti_2 357 362 PF11976 0.485
LIG_SUMO_SIM_par_1 436 443 PF11976 0.603
LIG_SUMO_SIM_par_1 609 615 PF11976 0.660
LIG_TYR_ITIM 501 506 PF00017 0.560
LIG_UBA3_1 610 618 PF00899 0.700
LIG_WRC_WIRS_1 19 24 PF05994 0.658
LIG_WW_3 91 95 PF00397 0.605
MOD_CDK_SPxxK_3 416 423 PF00069 0.608
MOD_CK1_1 142 148 PF00069 0.692
MOD_CK1_1 150 156 PF00069 0.597
MOD_CK1_1 161 167 PF00069 0.836
MOD_CK1_1 18 24 PF00069 0.557
MOD_CK1_1 219 225 PF00069 0.698
MOD_CK1_1 235 241 PF00069 0.677
MOD_CK1_1 3 9 PF00069 0.554
MOD_CK1_1 436 442 PF00069 0.546
MOD_CK1_1 585 591 PF00069 0.804
MOD_CK1_1 703 709 PF00069 0.740
MOD_CK1_1 714 720 PF00069 0.642
MOD_CK2_1 225 231 PF00069 0.798
MOD_CK2_1 299 305 PF00069 0.686
MOD_CK2_1 30 36 PF00069 0.577
MOD_CK2_1 391 397 PF00069 0.701
MOD_CK2_1 428 434 PF00069 0.539
MOD_CK2_1 436 442 PF00069 0.546
MOD_GlcNHglycan 2 5 PF01048 0.541
MOD_GlcNHglycan 325 328 PF01048 0.567
MOD_GlcNHglycan 517 520 PF01048 0.615
MOD_GlcNHglycan 584 587 PF01048 0.761
MOD_GlcNHglycan 620 624 PF01048 0.670
MOD_GlcNHglycan 658 661 PF01048 0.733
MOD_GlcNHglycan 697 700 PF01048 0.738
MOD_GlcNHglycan 703 706 PF01048 0.671
MOD_GSK3_1 132 139 PF00069 0.744
MOD_GSK3_1 14 21 PF00069 0.559
MOD_GSK3_1 142 149 PF00069 0.629
MOD_GSK3_1 150 157 PF00069 0.532
MOD_GSK3_1 219 226 PF00069 0.788
MOD_GSK3_1 318 325 PF00069 0.445
MOD_GSK3_1 367 374 PF00069 0.662
MOD_GSK3_1 581 588 PF00069 0.801
MOD_GSK3_1 649 656 PF00069 0.767
MOD_GSK3_1 675 682 PF00069 0.814
MOD_GSK3_1 695 702 PF00069 0.700
MOD_GSK3_1 714 721 PF00069 0.698
MOD_LATS_1 178 184 PF00433 0.803
MOD_N-GLC_1 656 661 PF02516 0.683
MOD_NEK2_1 371 376 PF00069 0.592
MOD_NEK2_1 391 396 PF00069 0.695
MOD_NEK2_1 572 577 PF00069 0.695
MOD_NEK2_1 695 700 PF00069 0.709
MOD_PIKK_1 173 179 PF00454 0.840
MOD_PIKK_1 182 188 PF00454 0.691
MOD_PIKK_1 332 338 PF00454 0.566
MOD_PIKK_1 651 657 PF00454 0.779
MOD_PIKK_1 714 720 PF00454 0.753
MOD_PKA_1 171 177 PF00069 0.737
MOD_PKA_2 171 177 PF00069 0.793
MOD_PKA_2 223 229 PF00069 0.803
MOD_PKA_2 235 241 PF00069 0.609
MOD_PKA_2 265 271 PF00069 0.676
MOD_PKA_2 414 420 PF00069 0.662
MOD_PKA_2 42 48 PF00069 0.559
MOD_PKB_1 169 177 PF00069 0.739
MOD_Plk_1 150 156 PF00069 0.787
MOD_Plk_1 413 419 PF00069 0.676
MOD_Plk_1 433 439 PF00069 0.629
MOD_Plk_2-3 84 90 PF00069 0.685
MOD_Plk_4 142 148 PF00069 0.695
MOD_Plk_4 15 21 PF00069 0.428
MOD_Plk_4 265 271 PF00069 0.623
MOD_Plk_4 3 9 PF00069 0.655
MOD_Plk_4 367 373 PF00069 0.578
MOD_Plk_4 458 464 PF00069 0.509
MOD_Plk_4 572 578 PF00069 0.695
MOD_Plk_4 84 90 PF00069 0.646
MOD_ProDKin_1 132 138 PF00069 0.741
MOD_ProDKin_1 416 422 PF00069 0.728
MOD_ProDKin_1 512 518 PF00069 0.453
MOD_ProDKin_1 649 655 PF00069 0.777
MOD_ProDKin_1 680 686 PF00069 0.765
MOD_ProDKin_1 703 709 PF00069 0.727
MOD_ProDKin_1 711 717 PF00069 0.647
MOD_SUMO_for_1 343 346 PF00179 0.675
MOD_SUMO_for_1 617 620 PF00179 0.702
MOD_SUMO_rev_2 31 39 PF00179 0.561
MOD_SUMO_rev_2 58 65 PF00179 0.552
TRG_DiLeu_BaEn_1 357 362 PF01217 0.691
TRG_DiLeu_BaEn_2 76 82 PF01217 0.670
TRG_DiLeu_BaEn_3 486 492 PF01217 0.410
TRG_ENDOCYTIC_2 503 506 PF00928 0.503
TRG_ENDOCYTIC_2 576 579 PF00928 0.701
TRG_ENDOCYTIC_2 86 89 PF00928 0.642
TRG_ER_diArg_1 124 127 PF00400 0.622
TRG_ER_diArg_1 169 172 PF00400 0.793
TRG_ER_diArg_1 191 194 PF00400 0.815
TRG_ER_diArg_1 282 285 PF00400 0.568
TRG_ER_diArg_1 329 331 PF00400 0.586
TRG_ER_diArg_1 350 352 PF00400 0.593
TRG_ER_diArg_1 380 382 PF00400 0.585
TRG_ER_diArg_1 590 592 PF00400 0.691
TRG_NLS_Bipartite_1 165 183 PF00514 0.800
TRG_NLS_MonoExtC_3 164 169 PF00514 0.774
TRG_NLS_MonoExtN_4 163 170 PF00514 0.837

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4W4 Leptomonas seymouri 57% 100%
A0A3S5H7Z3 Leishmania donovani 100% 100%
A4HMN1 Leishmania braziliensis 75% 100%
E9AF33 Leishmania major 93% 100%
E9B688 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS