Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IB92_LEIIN

TriTrypDb:

LINF_350024400

Length:

619

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IB92

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IB92

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	152	154	PF00675	0.681
CLV_NRD_NRD_1	302	304	PF00675	0.536
CLV_NRD_NRD_1	361	363	PF00675	0.603
CLV_NRD_NRD_1	371	373	PF00675	0.555
CLV_NRD_NRD_1	395	397	PF00675	0.605
CLV_NRD_NRD_1	439	441	PF00675	0.759
CLV_NRD_NRD_1	471	473	PF00675	0.687
CLV_NRD_NRD_1	496	498	PF00675	0.699
CLV_NRD_NRD_1	501	503	PF00675	0.649
CLV_NRD_NRD_1	530	532	PF00675	0.690
CLV_NRD_NRD_1	535	537	PF00675	0.688
CLV_NRD_NRD_1	556	558	PF00675	0.727
CLV_NRD_NRD_1	614	616	PF00675	0.681
CLV_NRD_NRD_1	91	93	PF00675	0.396
CLV_PCSK_FUR_1	499	503	PF00082	0.567
CLV_PCSK_KEX2_1	151	153	PF00082	0.697
CLV_PCSK_KEX2_1	302	304	PF00082	0.518
CLV_PCSK_KEX2_1	361	363	PF00082	0.603
CLV_PCSK_KEX2_1	371	373	PF00082	0.555
CLV_PCSK_KEX2_1	395	397	PF00082	0.605
CLV_PCSK_KEX2_1	439	441	PF00082	0.759
CLV_PCSK_KEX2_1	470	472	PF00082	0.690
CLV_PCSK_KEX2_1	495	497	PF00082	0.614
CLV_PCSK_KEX2_1	501	503	PF00082	0.583
CLV_PCSK_KEX2_1	535	537	PF00082	0.705
CLV_PCSK_KEX2_1	556	558	PF00082	0.630
CLV_PCSK_KEX2_1	614	616	PF00082	0.681
CLV_PCSK_PC7_1	497	503	PF00082	0.653
CLV_PCSK_PC7_1	531	537	PF00082	0.690
CLV_PCSK_SKI1_1	133	137	PF00082	0.549
CLV_PCSK_SKI1_1	206	210	PF00082	0.360
CLV_PCSK_SKI1_1	218	222	PF00082	0.388
CLV_PCSK_SKI1_1	290	294	PF00082	0.381
CLV_PCSK_SKI1_1	36	40	PF00082	0.524
CLV_PCSK_SKI1_1	590	594	PF00082	0.741
CLV_PCSK_SKI1_1	615	619	PF00082	0.669
DEG_APCC_DBOX_1	287	295	PF00400	0.557
DEG_SCF_TRCP1_1	47	53	PF00400	0.491
DEG_SPOP_SBC_1	462	466	PF00917	0.744
DEG_SPOP_SBC_1	61	65	PF00917	0.626
DEG_SPOP_SBC_1	84	88	PF00917	0.528
DOC_CKS1_1	476	481	PF01111	0.609
DOC_CYCLIN_yCln2_LP_2	444	450	PF00134	0.684
DOC_MAPK_gen_1	151	159	PF00069	0.672
DOC_MAPK_gen_1	286	293	PF00069	0.405
DOC_MAPK_gen_1	340	348	PF00069	0.529
DOC_MAPK_MEF2A_6	342	350	PF00069	0.526
DOC_MIT_MIM_1	201	210	PF04212	0.515
DOC_PP2B_LxvP_1	552	555	PF13499	0.552
DOC_PP4_FxxP_1	221	224	PF00568	0.409
DOC_PP4_FxxP_1	268	271	PF00568	0.490
DOC_PP4_FxxP_1	373	376	PF00568	0.696
DOC_PP4_FxxP_1	476	479	PF00568	0.619
DOC_USP7_MATH_1	135	139	PF00917	0.604
DOC_USP7_MATH_1	163	167	PF00917	0.663
DOC_USP7_MATH_1	353	357	PF00917	0.580
DOC_USP7_MATH_1	387	391	PF00917	0.655
DOC_USP7_MATH_1	414	418	PF00917	0.745
DOC_USP7_MATH_1	45	49	PF00917	0.657
DOC_USP7_MATH_1	463	467	PF00917	0.759
DOC_USP7_MATH_1	485	489	PF00917	0.654
DOC_USP7_MATH_1	571	575	PF00917	0.688
DOC_USP7_MATH_1	592	596	PF00917	0.684
DOC_USP7_MATH_1	606	610	PF00917	0.692
DOC_USP7_MATH_1	61	65	PF00917	0.576
DOC_USP7_UBL2_3	93	97	PF12436	0.445
DOC_WW_Pin1_4	107	112	PF00397	0.465
DOC_WW_Pin1_4	133	138	PF00397	0.571
DOC_WW_Pin1_4	249	254	PF00397	0.697
DOC_WW_Pin1_4	443	448	PF00397	0.693
DOC_WW_Pin1_4	475	480	PF00397	0.618
DOC_WW_Pin1_4	5	10	PF00397	0.386
DOC_WW_Pin1_4	513	518	PF00397	0.609
DOC_WW_Pin1_4	567	572	PF00397	0.651
DOC_WW_Pin1_4	598	603	PF00397	0.605
LIG_14-3-3_CanoR_1	16	25	PF00244	0.482
LIG_14-3-3_CanoR_1	182	191	PF00244	0.477
LIG_14-3-3_CanoR_1	206	211	PF00244	0.359
LIG_14-3-3_CanoR_1	361	365	PF00244	0.596
LIG_14-3-3_CanoR_1	366	373	PF00244	0.568
LIG_14-3-3_CanoR_1	395	402	PF00244	0.631
LIG_14-3-3_CanoR_1	439	445	PF00244	0.669
LIG_14-3-3_CanoR_1	470	479	PF00244	0.742
LIG_14-3-3_CanoR_1	547	553	PF00244	0.778
LIG_14-3-3_CanoR_1	556	562	PF00244	0.725
LIG_14-3-3_CanoR_1	579	588	PF00244	0.609
LIG_14-3-3_CanoR_1	590	598	PF00244	0.704
LIG_14-3-3_CanoR_1	72	78	PF00244	0.521
LIG_14-3-3_CanoR_1	92	96	PF00244	0.456
LIG_BIR_II_1	1	5	PF00653	0.475
LIG_BRCT_BRCA1_1	472	476	PF00533	0.750
LIG_CaM_IQ_9	316	331	PF13499	0.424
LIG_FHA_1	215	221	PF00498	0.407
LIG_FHA_1	549	555	PF00498	0.667
LIG_FHA_1	57	63	PF00498	0.588
LIG_FHA_1	599	605	PF00498	0.590
LIG_FHA_1	78	84	PF00498	0.447
LIG_FHA_2	117	123	PF00498	0.394
LIG_FHA_2	168	174	PF00498	0.708
LIG_FHA_2	188	194	PF00498	0.543
LIG_FHA_2	472	478	PF00498	0.691
LIG_FHA_2	76	82	PF00498	0.524
LIG_IBAR_NPY_1	399	401	PF08397	0.641
LIG_Integrin_RGD_1	502	504	PF01839	0.748
LIG_LIR_Apic_2	267	271	PF02991	0.551
LIG_LIR_Apic_2	473	479	PF02991	0.627
LIG_LIR_Gen_1	204	214	PF02991	0.438
LIG_LIR_Gen_1	94	103	PF02991	0.382
LIG_LIR_Nem_3	204	210	PF02991	0.395
LIG_LIR_Nem_3	410	416	PF02991	0.658
LIG_LIR_Nem_3	94	98	PF02991	0.399
LIG_Pex14_2	264	268	PF04695	0.493
LIG_Rb_pABgroove_1	97	105	PF01858	0.377
LIG_SH2_CRK	103	107	PF00017	0.434
LIG_SH2_CRK	413	417	PF00017	0.630
LIG_SH2_STAP1	103	107	PF00017	0.492
LIG_SH2_STAP1	212	216	PF00017	0.412
LIG_SH2_STAT3	422	425	PF00017	0.657
LIG_SH2_STAT5	13	16	PF00017	0.375
LIG_SH2_STAT5	401	404	PF00017	0.634
LIG_SH3_3	3	9	PF00018	0.387
LIG_SH3_3	444	450	PF00018	0.748
LIG_SH3_3	476	482	PF00018	0.659
LIG_SH3_3	527	533	PF00018	0.662
LIG_SUMO_SIM_anti_2	289	297	PF11976	0.384
LIG_SUMO_SIM_par_1	189	197	PF11976	0.535
LIG_SUMO_SIM_par_1	78	88	PF11976	0.413
LIG_WRC_WIRS_1	265	270	PF05994	0.492
MOD_CDK_SPK_2	598	603	PF00069	0.640
MOD_CDK_SPxK_1	133	139	PF00069	0.580
MOD_CDK_SPxxK_3	5	12	PF00069	0.389
MOD_CK1_1	2	8	PF00069	0.508
MOD_CK1_1	269	275	PF00069	0.678
MOD_CK1_1	356	362	PF00069	0.530
MOD_CK1_1	378	384	PF00069	0.653
MOD_CK1_1	406	412	PF00069	0.681
MOD_CK1_1	427	433	PF00069	0.711
MOD_CK1_1	464	470	PF00069	0.689
MOD_CK1_1	506	512	PF00069	0.696
MOD_CK1_1	538	544	PF00069	0.754
MOD_CK1_1	546	552	PF00069	0.672
MOD_CK1_1	574	580	PF00069	0.618
MOD_CK1_1	581	587	PF00069	0.614
MOD_CK2_1	116	122	PF00069	0.394
MOD_CK2_1	16	22	PF00069	0.423
MOD_CK2_1	167	173	PF00069	0.660
MOD_CK2_1	187	193	PF00069	0.553
MOD_CK2_1	505	511	PF00069	0.579
MOD_CK2_1	73	79	PF00069	0.471
MOD_GlcNHglycan	160	163	PF01048	0.699
MOD_GlcNHglycan	233	236	PF01048	0.551
MOD_GlcNHglycan	249	252	PF01048	0.655
MOD_GlcNHglycan	377	380	PF01048	0.577
MOD_GlcNHglycan	385	388	PF01048	0.678
MOD_GlcNHglycan	389	392	PF01048	0.685
MOD_GlcNHglycan	41	45	PF01048	0.652
MOD_GlcNHglycan	426	429	PF01048	0.722
MOD_GlcNHglycan	435	438	PF01048	0.660
MOD_GlcNHglycan	46	50	PF01048	0.574
MOD_GlcNHglycan	538	541	PF01048	0.648
MOD_GlcNHglycan	564	568	PF01048	0.760
MOD_GlcNHglycan	581	584	PF01048	0.495
MOD_GlcNHglycan	608	611	PF01048	0.740
MOD_GlcNHglycan	65	68	PF01048	0.636
MOD_GlcNHglycan	87	90	PF01048	0.448
MOD_GSK3_1	163	170	PF00069	0.665
MOD_GSK3_1	227	234	PF00069	0.616
MOD_GSK3_1	243	250	PF00069	0.710
MOD_GSK3_1	272	279	PF00069	0.650
MOD_GSK3_1	28	35	PF00069	0.532
MOD_GSK3_1	356	363	PF00069	0.601
MOD_GSK3_1	371	378	PF00069	0.487
MOD_GSK3_1	383	390	PF00069	0.730
MOD_GSK3_1	461	468	PF00069	0.719
MOD_GSK3_1	471	478	PF00069	0.591
MOD_GSK3_1	536	543	PF00069	0.644
MOD_GSK3_1	546	553	PF00069	0.682
MOD_GSK3_1	56	63	PF00069	0.595
MOD_GSK3_1	563	570	PF00069	0.657
MOD_GSK3_1	571	578	PF00069	0.598
MOD_GSK3_1	588	595	PF00069	0.566
MOD_GSK3_1	73	80	PF00069	0.514
MOD_N-GLC_1	32	37	PF02516	0.586
MOD_NEK2_1	116	121	PF00069	0.542
MOD_NEK2_1	167	172	PF00069	0.692
MOD_NEK2_1	26	31	PF00069	0.522
MOD_NEK2_1	264	269	PF00069	0.572
MOD_NEK2_1	588	593	PF00069	0.678
MOD_NEK2_1	62	67	PF00069	0.661
MOD_NEK2_1	73	78	PF00069	0.366
MOD_NEK2_1	83	88	PF00069	0.376
MOD_PIKK_1	353	359	PF00454	0.598
MOD_PIKK_1	366	372	PF00454	0.486
MOD_PKA_1	371	377	PF00069	0.596
MOD_PKA_1	470	476	PF00069	0.746
MOD_PKA_1	495	501	PF00069	0.599
MOD_PKA_1	535	541	PF00069	0.753
MOD_PKA_2	360	366	PF00069	0.546
MOD_PKA_2	371	377	PF00069	0.610
MOD_PKA_2	394	400	PF00069	0.596
MOD_PKA_2	406	412	PF00069	0.641
MOD_PKA_2	433	439	PF00069	0.754
MOD_PKA_2	470	476	PF00069	0.633
MOD_PKA_2	495	501	PF00069	0.751
MOD_PKA_2	535	541	PF00069	0.654
MOD_PKA_2	546	552	PF00069	0.668
MOD_PKA_2	578	584	PF00069	0.641
MOD_PKA_2	91	97	PF00069	0.432
MOD_PKB_1	243	251	PF00069	0.607
MOD_PKB_1	495	503	PF00069	0.631
MOD_Plk_1	2	8	PF00069	0.451
MOD_Plk_1	257	263	PF00069	0.611
MOD_Plk_4	187	193	PF00069	0.553
MOD_Plk_4	2	8	PF00069	0.453
MOD_Plk_4	50	56	PF00069	0.620
MOD_ProDKin_1	107	113	PF00069	0.458
MOD_ProDKin_1	133	139	PF00069	0.580
MOD_ProDKin_1	249	255	PF00069	0.695
MOD_ProDKin_1	443	449	PF00069	0.691
MOD_ProDKin_1	475	481	PF00069	0.613
MOD_ProDKin_1	5	11	PF00069	0.385
MOD_ProDKin_1	513	519	PF00069	0.609
MOD_ProDKin_1	567	573	PF00069	0.652
MOD_ProDKin_1	598	604	PF00069	0.607
TRG_DiLeu_BaEn_1	304	309	PF01217	0.537
TRG_ENDOCYTIC_2	103	106	PF00928	0.431
TRG_ENDOCYTIC_2	413	416	PF00928	0.663
TRG_ER_diArg_1	151	153	PF00400	0.637
TRG_ER_diArg_1	242	245	PF00400	0.615
TRG_ER_diArg_1	285	288	PF00400	0.558
TRG_ER_diArg_1	301	303	PF00400	0.356
TRG_ER_diArg_1	339	342	PF00400	0.536
TRG_ER_diArg_1	371	373	PF00400	0.604
TRG_ER_diArg_1	470	472	PF00400	0.672
TRG_ER_diArg_1	494	497	PF00400	0.611
TRG_ER_diArg_1	499	502	PF00400	0.700
TRG_ER_diArg_1	555	557	PF00400	0.717
TRG_ER_diArg_1	613	615	PF00400	0.667
TRG_NES_CRM1_1	320	335	PF08389	0.615
TRG_Pf-PMV_PEXEL_1	206	211	PF00026	0.419
TRG_Pf-PMV_PEXEL_1	403	408	PF00026	0.653
TRG_Pf-PMV_PEXEL_1	559	564	PF00026	0.630

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBH3	Leptomonas seymouri	46%	94%
A0A1X0P5W2	Trypanosomatidae	34%	100%
A0A3S7X983	Leishmania donovani	100%	100%
A4HML5	Leishmania braziliensis	76%	100%
E9AF16	Leishmania major	91%	100%
E9B672	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%