LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IB91_LEIIN
TriTrypDb:
LINF_350024300
Length:
449

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IB91
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IB91

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 110 112 PF00675 0.702
CLV_NRD_NRD_1 438 440 PF00675 0.671
CLV_PCSK_FUR_1 108 112 PF00082 0.637
CLV_PCSK_KEX2_1 110 112 PF00082 0.702
CLV_Separin_Metazoa 187 191 PF03568 0.512
CLV_Separin_Metazoa 317 321 PF03568 0.517
DEG_APCC_KENBOX_2 409 413 PF00400 0.654
DOC_MAPK_gen_1 439 449 PF00069 0.632
DOC_PP2B_LxvP_1 97 100 PF13499 0.639
DOC_PP4_FxxP_1 341 344 PF00568 0.531
DOC_PP4_FxxP_1 346 349 PF00568 0.472
DOC_USP7_MATH_1 136 140 PF00917 0.538
DOC_USP7_MATH_1 162 166 PF00917 0.438
DOC_USP7_MATH_1 243 247 PF00917 0.769
DOC_USP7_MATH_1 263 267 PF00917 0.703
DOC_USP7_MATH_1 268 272 PF00917 0.641
DOC_USP7_MATH_1 283 287 PF00917 0.569
DOC_USP7_MATH_1 297 301 PF00917 0.545
DOC_USP7_MATH_1 385 389 PF00917 0.460
DOC_USP7_MATH_1 59 63 PF00917 0.532
DOC_USP7_MATH_1 83 87 PF00917 0.652
DOC_USP7_MATH_1 88 92 PF00917 0.624
DOC_WW_Pin1_4 125 130 PF00397 0.624
DOC_WW_Pin1_4 141 146 PF00397 0.702
DOC_WW_Pin1_4 156 161 PF00397 0.444
DOC_WW_Pin1_4 245 250 PF00397 0.685
DOC_WW_Pin1_4 272 277 PF00397 0.773
DOC_WW_Pin1_4 281 286 PF00397 0.652
DOC_WW_Pin1_4 365 370 PF00397 0.458
LIG_14-3-3_CanoR_1 63 73 PF00244 0.520
LIG_BIR_II_1 1 5 PF00653 0.583
LIG_BIR_III_4 58 62 PF00653 0.523
LIG_BRCT_BRCA1_1 413 417 PF00533 0.538
LIG_deltaCOP1_diTrp_1 328 334 PF00928 0.437
LIG_FHA_1 10 16 PF00498 0.614
LIG_FHA_1 152 158 PF00498 0.537
LIG_FHA_1 432 438 PF00498 0.569
LIG_FHA_1 94 100 PF00498 0.751
LIG_FHA_2 113 119 PF00498 0.605
LIG_LIR_Apic_2 398 403 PF02991 0.611
LIG_LIR_Gen_1 76 85 PF02991 0.507
LIG_LIR_Nem_3 171 177 PF02991 0.476
LIG_LIR_Nem_3 246 250 PF02991 0.644
LIG_LIR_Nem_3 328 333 PF02991 0.489
LIG_LIR_Nem_3 76 82 PF02991 0.487
LIG_MAD2 424 432 PF02301 0.554
LIG_PDZ_Class_2 444 449 PF00595 0.656
LIG_Pex14_1 330 334 PF04695 0.440
LIG_Pex14_2 206 210 PF04695 0.454
LIG_PTB_Apo_2 188 195 PF02174 0.529
LIG_SH2_CRK 247 251 PF00017 0.646
LIG_SH2_CRK 322 326 PF00017 0.418
LIG_SH2_GRB2like 73 76 PF00017 0.583
LIG_SH2_NCK_1 79 83 PF00017 0.578
LIG_SH2_SRC 79 82 PF00017 0.512
LIG_SH2_STAP1 73 77 PF00017 0.499
LIG_SH2_STAP1 79 83 PF00017 0.504
LIG_SH2_STAT3 333 336 PF00017 0.450
LIG_SH2_STAT5 114 117 PF00017 0.696
LIG_SH2_STAT5 177 180 PF00017 0.445
LIG_SH2_STAT5 333 336 PF00017 0.450
LIG_SH2_STAT5 377 380 PF00017 0.504
LIG_SH2_STAT5 39 42 PF00017 0.455
LIG_SH3_3 140 146 PF00018 0.668
LIG_SH3_3 247 253 PF00018 0.559
LIG_SH3_3 271 277 PF00018 0.686
LIG_SH3_3 282 288 PF00018 0.642
LIG_SH3_3 3 9 PF00018 0.648
LIG_SH3_3 387 393 PF00018 0.438
LIG_TRAF2_1 237 240 PF00917 0.645
MOD_CDC14_SPxK_1 248 251 PF00782 0.692
MOD_CDK_SPxK_1 245 251 PF00069 0.696
MOD_CK1_1 139 145 PF00069 0.664
MOD_CK1_1 148 154 PF00069 0.581
MOD_CK2_1 112 118 PF00069 0.603
MOD_CK2_1 283 289 PF00069 0.632
MOD_GlcNHglycan 103 106 PF01048 0.753
MOD_GlcNHglycan 138 141 PF01048 0.677
MOD_GlcNHglycan 164 167 PF01048 0.549
MOD_GlcNHglycan 253 256 PF01048 0.671
MOD_GlcNHglycan 31 34 PF01048 0.717
MOD_GlcNHglycan 387 390 PF01048 0.438
MOD_GlcNHglycan 90 93 PF01048 0.638
MOD_GSK3_1 141 148 PF00069 0.675
MOD_GSK3_1 152 159 PF00069 0.510
MOD_GSK3_1 194 201 PF00069 0.546
MOD_GSK3_1 245 252 PF00069 0.637
MOD_GSK3_1 263 270 PF00069 0.601
MOD_GSK3_1 277 284 PF00069 0.673
MOD_GSK3_1 83 90 PF00069 0.631
MOD_N-GLC_1 194 199 PF02516 0.544
MOD_N-GLC_1 411 416 PF02516 0.556
MOD_NEK2_1 1 6 PF00069 0.581
MOD_NEK2_1 194 199 PF00069 0.544
MOD_NEK2_1 379 384 PF00069 0.635
MOD_PIKK_1 109 115 PF00454 0.626
MOD_PKA_1 439 445 PF00069 0.655
MOD_PKA_2 109 115 PF00069 0.626
MOD_PKA_2 148 154 PF00069 0.652
MOD_PKA_2 213 219 PF00069 0.444
MOD_Plk_1 194 200 PF00069 0.563
MOD_Plk_1 379 385 PF00069 0.432
MOD_Plk_4 1 7 PF00069 0.581
MOD_Plk_4 152 158 PF00069 0.601
MOD_Plk_4 213 219 PF00069 0.482
MOD_Plk_4 431 437 PF00069 0.646
MOD_ProDKin_1 125 131 PF00069 0.622
MOD_ProDKin_1 141 147 PF00069 0.701
MOD_ProDKin_1 156 162 PF00069 0.434
MOD_ProDKin_1 245 251 PF00069 0.686
MOD_ProDKin_1 272 278 PF00069 0.772
MOD_ProDKin_1 281 287 PF00069 0.652
MOD_ProDKin_1 365 371 PF00069 0.454
MOD_SUMO_for_1 258 261 PF00179 0.664
TRG_DiLeu_BaEn_1 444 449 PF01217 0.631
TRG_DiLeu_BaEn_4 239 245 PF01217 0.644
TRG_DiLeu_BaLyEn_6 404 409 PF01217 0.639
TRG_ENDOCYTIC_2 247 250 PF00928 0.644
TRG_ENDOCYTIC_2 322 325 PF00928 0.422
TRG_ENDOCYTIC_2 79 82 PF00928 0.575
TRG_ER_diArg_1 108 111 PF00400 0.784

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HZQ4 Leptomonas seymouri 48% 98%
A0A3S5H7Z2 Leishmania donovani 98% 100%
A4HML4 Leishmania braziliensis 77% 100%
E9AF15 Leishmania major 93% 100%
E9B671 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS