Putative 60S Ribosomal protein L36

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L36 - putative

Species:

Leishmania infantum

UniProt:

A4IB89_LEIIN

TriTrypDb:

LINF_210013000

Length:

105

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S Ribosomal L36

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 6
Forrest at al. (procyclic)	yes	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 25

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 18
NetGPI	no	yes: 0, no: 18

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Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0005737	cytoplasm	2	2
GO:0005840	ribosome	5	17
GO:0015934	large ribosomal subunit	4	2
GO:0022625	cytosolic large ribosomal subunit	5	2
GO:0032991	protein-containing complex	1	19
GO:0043226	organelle	2	18
GO:0043228	non-membrane-bounded organelle	3	18
GO:0043229	intracellular organelle	3	18
GO:0043232	intracellular non-membrane-bounded organelle	4	18

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Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A4IB89

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IB89

PDB structure(s): 6az3_i

Function

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Biological processes
Term	Name	Level	Count
GO:0002181	cytoplasmic translation	5	2
GO:0006412	translation	4	19
GO:0006518	peptide metabolic process	4	19
GO:0006807	nitrogen compound metabolic process	2	19
GO:0008152	metabolic process	1	19
GO:0009058	biosynthetic process	2	19
GO:0009059	macromolecule biosynthetic process	4	19
GO:0009987	cellular process	1	19
GO:0019538	protein metabolic process	3	19
GO:0034641	cellular nitrogen compound metabolic process	3	19

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Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	19
GO:0005198	structural molecule activity	1	19

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	22	24	PF00675	0.232
CLV_PCSK_KEX2_1	22	24	PF00082	0.233
CLV_PCSK_KEX2_1	58	60	PF00082	0.223
CLV_PCSK_KEX2_1	70	72	PF00082	0.234
CLV_PCSK_KEX2_1	78	80	PF00082	0.247
CLV_PCSK_KEX2_1	89	91	PF00082	0.234
CLV_PCSK_PC1ET2_1	58	60	PF00082	0.283
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.223
CLV_PCSK_PC1ET2_1	78	80	PF00082	0.223
CLV_PCSK_PC1ET2_1	89	91	PF00082	0.225

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM67	Leptomonas seymouri	96%	100%
A0A0S4JFE8	Bodo saltans	69%	94%
A0A1X0NZ05	Trypanosomatidae	82%	91%
A0A1X0P5V0	Trypanosomatidae	82%	97%
A0A3Q8IDW6	Leishmania donovani	98%	100%
A0A3R7MLS5	Trypanosoma rangeli	82%	92%
A0A3S7X961	Leishmania donovani	100%	100%
A4HBR9	Leishmania braziliensis	96%	100%
A4HML2	Leishmania braziliensis	96%	100%
A4HZ73	Leishmania infantum	98%	100%

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