LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IB87_LEIIN
TriTrypDb:
LINF_350023600
Length:
739

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IB87
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IB87

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 437 441 PF00656 0.682
CLV_NRD_NRD_1 294 296 PF00675 0.610
CLV_NRD_NRD_1 444 446 PF00675 0.633
CLV_NRD_NRD_1 562 564 PF00675 0.757
CLV_NRD_NRD_1 639 641 PF00675 0.607
CLV_NRD_NRD_1 683 685 PF00675 0.511
CLV_NRD_NRD_1 703 705 PF00675 0.352
CLV_NRD_NRD_1 729 731 PF00675 0.552
CLV_PCSK_FUR_1 560 564 PF00082 0.649
CLV_PCSK_KEX2_1 294 296 PF00082 0.610
CLV_PCSK_KEX2_1 33 35 PF00082 0.616
CLV_PCSK_KEX2_1 443 445 PF00082 0.632
CLV_PCSK_KEX2_1 562 564 PF00082 0.757
CLV_PCSK_KEX2_1 572 574 PF00082 0.588
CLV_PCSK_KEX2_1 639 641 PF00082 0.607
CLV_PCSK_KEX2_1 683 685 PF00082 0.511
CLV_PCSK_KEX2_1 729 731 PF00082 0.552
CLV_PCSK_PC1ET2_1 33 35 PF00082 0.616
CLV_PCSK_PC1ET2_1 572 574 PF00082 0.603
CLV_PCSK_PC7_1 568 574 PF00082 0.654
CLV_PCSK_SKI1_1 347 351 PF00082 0.622
CLV_PCSK_SKI1_1 456 460 PF00082 0.579
CLV_PCSK_SKI1_1 517 521 PF00082 0.471
CLV_PCSK_SKI1_1 609 613 PF00082 0.730
CLV_PCSK_SKI1_1 620 624 PF00082 0.505
CLV_PCSK_SKI1_1 91 95 PF00082 0.674
DEG_APCC_DBOX_1 516 524 PF00400 0.453
DEG_Nend_Nbox_1 1 3 PF02207 0.612
DEG_SPOP_SBC_1 342 346 PF00917 0.602
DEG_SPOP_SBC_1 348 352 PF00917 0.605
DEG_SPOP_SBC_1 72 76 PF00917 0.640
DOC_ANK_TNKS_1 414 421 PF00023 0.603
DOC_CDC14_PxL_1 52 60 PF14671 0.610
DOC_CKS1_1 159 164 PF01111 0.650
DOC_CKS1_1 262 267 PF01111 0.659
DOC_CKS1_1 281 286 PF01111 0.685
DOC_CYCLIN_yCln2_LP_2 94 100 PF00134 0.645
DOC_MAPK_gen_1 514 523 PF00069 0.472
DOC_MAPK_gen_1 704 712 PF00069 0.492
DOC_MAPK_gen_1 716 724 PF00069 0.378
DOC_MAPK_HePTP_8 511 523 PF00069 0.448
DOC_MAPK_JIP1_4 96 102 PF00069 0.599
DOC_MAPK_MEF2A_6 514 523 PF00069 0.454
DOC_MAPK_MEF2A_6 716 724 PF00069 0.492
DOC_PP1_RVXF_1 520 526 PF00149 0.461
DOC_PP2B_LxvP_1 98 101 PF13499 0.656
DOC_SPAK_OSR1_1 492 496 PF12202 0.500
DOC_USP7_MATH_1 237 241 PF00917 0.653
DOC_USP7_MATH_1 301 305 PF00917 0.510
DOC_USP7_MATH_1 341 345 PF00917 0.632
DOC_USP7_MATH_1 348 352 PF00917 0.657
DOC_USP7_MATH_1 353 357 PF00917 0.638
DOC_USP7_MATH_1 425 429 PF00917 0.643
DOC_USP7_MATH_1 47 51 PF00917 0.612
DOC_USP7_MATH_1 543 547 PF00917 0.638
DOC_USP7_MATH_1 549 553 PF00917 0.655
DOC_USP7_MATH_1 593 597 PF00917 0.657
DOC_USP7_MATH_1 631 635 PF00917 0.628
DOC_USP7_MATH_1 656 660 PF00917 0.644
DOC_USP7_UBL2_3 701 705 PF12436 0.474
DOC_WW_Pin1_4 158 163 PF00397 0.686
DOC_WW_Pin1_4 191 196 PF00397 0.640
DOC_WW_Pin1_4 241 246 PF00397 0.727
DOC_WW_Pin1_4 261 266 PF00397 0.574
DOC_WW_Pin1_4 280 285 PF00397 0.694
DOC_WW_Pin1_4 523 528 PF00397 0.509
DOC_WW_Pin1_4 553 558 PF00397 0.589
LIG_14-3-3_CanoR_1 170 176 PF00244 0.653
LIG_14-3-3_CanoR_1 300 310 PF00244 0.556
LIG_14-3-3_CanoR_1 426 431 PF00244 0.587
LIG_14-3-3_CanoR_1 630 636 PF00244 0.614
LIG_14-3-3_CanoR_1 640 646 PF00244 0.498
LIG_14-3-3_CanoR_1 683 692 PF00244 0.539
LIG_Actin_WH2_2 305 321 PF00022 0.464
LIG_Actin_WH2_2 394 412 PF00022 0.514
LIG_Actin_WH2_2 45 61 PF00022 0.516
LIG_APCC_ABBA_1 493 498 PF00400 0.478
LIG_APCC_ABBAyCdc20_2 492 498 PF00400 0.487
LIG_BIR_III_4 220 224 PF00653 0.591
LIG_CaM_IQ_9 722 737 PF13499 0.516
LIG_CSL_BTD_1 524 527 PF09270 0.467
LIG_CtBP_PxDLS_1 626 630 PF00389 0.596
LIG_EH1_1 15 23 PF00400 0.493
LIG_eIF4E_1 403 409 PF01652 0.581
LIG_eIF4E_1 515 521 PF01652 0.482
LIG_FHA_1 214 220 PF00498 0.670
LIG_FHA_1 242 248 PF00498 0.733
LIG_FHA_1 291 297 PF00498 0.567
LIG_FHA_1 33 39 PF00498 0.660
LIG_FHA_1 388 394 PF00498 0.476
LIG_FHA_1 707 713 PF00498 0.507
LIG_FHA_2 435 441 PF00498 0.682
LIG_FHA_2 455 461 PF00498 0.371
LIG_FHA_2 482 488 PF00498 0.539
LIG_FHA_2 674 680 PF00498 0.513
LIG_FHA_2 683 689 PF00498 0.547
LIG_FHA_2 692 698 PF00498 0.468
LIG_FHA_2 723 729 PF00498 0.462
LIG_LIR_Apic_2 158 162 PF02991 0.650
LIG_LIR_Gen_1 136 145 PF02991 0.551
LIG_LIR_Gen_1 308 318 PF02991 0.455
LIG_LIR_Nem_3 136 141 PF02991 0.546
LIG_LIR_Nem_3 308 313 PF02991 0.462
LIG_LIR_Nem_3 460 465 PF02991 0.533
LIG_NBox_RRM_1 575 585 PF00076 0.524
LIG_Pex14_2 12 16 PF04695 0.490
LIG_SH2_CRK 462 466 PF00017 0.484
LIG_SH2_PTP2 138 141 PF00017 0.504
LIG_SH2_STAP1 515 519 PF00017 0.489
LIG_SH2_STAT3 515 518 PF00017 0.494
LIG_SH2_STAT5 138 141 PF00017 0.504
LIG_SH2_STAT5 536 539 PF00017 0.640
LIG_SH2_STAT5 674 677 PF00017 0.628
LIG_SH3_3 252 258 PF00018 0.690
LIG_SH3_3 278 284 PF00018 0.702
LIG_SH3_3 462 468 PF00018 0.375
LIG_SH3_3 485 491 PF00018 0.565
LIG_SH3_3 50 56 PF00018 0.653
LIG_SH3_3 596 602 PF00018 0.658
LIG_Sin3_3 310 317 PF02671 0.439
LIG_SUMO_SIM_anti_2 707 714 PF11976 0.523
LIG_SUMO_SIM_par_1 707 714 PF11976 0.529
LIG_WRC_WIRS_1 306 311 PF05994 0.455
MOD_CDC14_SPxK_1 194 197 PF00782 0.637
MOD_CDK_SPK_2 261 266 PF00069 0.602
MOD_CDK_SPxK_1 158 164 PF00069 0.651
MOD_CDK_SPxK_1 191 197 PF00069 0.640
MOD_CDK_SPxxK_3 163 170 PF00069 0.663
MOD_CDK_SPxxK_3 553 560 PF00069 0.542
MOD_CK1_1 174 180 PF00069 0.601
MOD_CK1_1 256 262 PF00069 0.650
MOD_CK1_1 308 314 PF00069 0.457
MOD_CK1_1 32 38 PF00069 0.705
MOD_CK1_1 379 385 PF00069 0.554
MOD_CK1_1 404 410 PF00069 0.599
MOD_CK1_1 451 457 PF00069 0.600
MOD_CK1_1 528 534 PF00069 0.540
MOD_CK1_1 634 640 PF00069 0.603
MOD_CK2_1 203 209 PF00069 0.660
MOD_CK2_1 673 679 PF00069 0.544
MOD_CK2_1 682 688 PF00069 0.547
MOD_CK2_1 691 697 PF00069 0.463
MOD_CK2_1 722 728 PF00069 0.455
MOD_Cter_Amidation 141 144 PF01082 0.512
MOD_DYRK1A_RPxSP_1 280 284 PF00069 0.658
MOD_GlcNHglycan 145 148 PF01048 0.585
MOD_GlcNHglycan 209 212 PF01048 0.660
MOD_GlcNHglycan 284 287 PF01048 0.677
MOD_GlcNHglycan 323 326 PF01048 0.465
MOD_GlcNHglycan 355 358 PF01048 0.695
MOD_GlcNHglycan 360 363 PF01048 0.607
MOD_GlcNHglycan 416 419 PF01048 0.662
MOD_GlcNHglycan 423 426 PF01048 0.608
MOD_GlcNHglycan 449 453 PF01048 0.629
MOD_GlcNHglycan 48 52 PF01048 0.622
MOD_GlcNHglycan 502 505 PF01048 0.415
MOD_GlcNHglycan 530 533 PF01048 0.554
MOD_GlcNHglycan 545 548 PF01048 0.677
MOD_GlcNHglycan 585 588 PF01048 0.717
MOD_GlcNHglycan 595 598 PF01048 0.641
MOD_GlcNHglycan 646 649 PF01048 0.576
MOD_GlcNHglycan 658 661 PF01048 0.504
MOD_GlcNHglycan 81 84 PF01048 0.750
MOD_GSK3_1 170 177 PF00069 0.628
MOD_GSK3_1 203 210 PF00069 0.645
MOD_GSK3_1 221 228 PF00069 0.486
MOD_GSK3_1 237 244 PF00069 0.648
MOD_GSK3_1 25 32 PF00069 0.684
MOD_GSK3_1 256 263 PF00069 0.588
MOD_GSK3_1 276 283 PF00069 0.702
MOD_GSK3_1 301 308 PF00069 0.475
MOD_GSK3_1 343 350 PF00069 0.626
MOD_GSK3_1 353 360 PF00069 0.568
MOD_GSK3_1 379 386 PF00069 0.553
MOD_GSK3_1 387 394 PF00069 0.412
MOD_GSK3_1 421 428 PF00069 0.660
MOD_GSK3_1 447 454 PF00069 0.622
MOD_GSK3_1 549 556 PF00069 0.636
MOD_GSK3_1 564 571 PF00069 0.675
MOD_GSK3_1 605 612 PF00069 0.739
MOD_GSK3_1 630 637 PF00069 0.626
MOD_GSK3_1 673 680 PF00069 0.513
MOD_GSK3_1 682 689 PF00069 0.647
MOD_GSK3_1 718 725 PF00069 0.452
MOD_N-GLC_1 553 558 PF02516 0.542
MOD_NEK2_1 171 176 PF00069 0.578
MOD_NEK2_1 213 218 PF00069 0.546
MOD_NEK2_1 318 323 PF00069 0.471
MOD_NEK2_1 486 491 PF00069 0.615
MOD_NEK2_1 607 612 PF00069 0.672
MOD_NEK2_1 629 634 PF00069 0.595
MOD_NEK2_2 491 496 PF00069 0.499
MOD_PIKK_1 184 190 PF00454 0.669
MOD_PIKK_1 370 376 PF00454 0.488
MOD_PIKK_1 722 728 PF00454 0.455
MOD_PK_1 34 40 PF00069 0.622
MOD_PK_1 718 724 PF00069 0.389
MOD_PKA_1 143 149 PF00069 0.464
MOD_PKA_1 225 231 PF00069 0.534
MOD_PKA_2 177 183 PF00069 0.663
MOD_PKA_2 318 324 PF00069 0.566
MOD_PKA_2 414 420 PF00069 0.617
MOD_PKA_2 425 431 PF00069 0.573
MOD_PKA_2 491 497 PF00069 0.490
MOD_PKA_2 629 635 PF00069 0.568
MOD_PKA_2 682 688 PF00069 0.629
MOD_PKB_1 445 453 PF00069 0.628
MOD_Plk_1 404 410 PF00069 0.599
MOD_Plk_1 47 53 PF00069 0.649
MOD_Plk_1 706 712 PF00069 0.531
MOD_Plk_1 718 724 PF00069 0.394
MOD_Plk_4 171 177 PF00069 0.577
MOD_Plk_4 213 219 PF00069 0.607
MOD_Plk_4 305 311 PF00069 0.584
MOD_Plk_4 388 394 PF00069 0.485
MOD_Plk_4 404 410 PF00069 0.433
MOD_Plk_4 609 615 PF00069 0.646
MOD_Plk_4 641 647 PF00069 0.514
MOD_Plk_4 677 683 PF00069 0.523
MOD_Plk_4 691 697 PF00069 0.411
MOD_ProDKin_1 158 164 PF00069 0.686
MOD_ProDKin_1 191 197 PF00069 0.640
MOD_ProDKin_1 241 247 PF00069 0.724
MOD_ProDKin_1 261 267 PF00069 0.573
MOD_ProDKin_1 280 286 PF00069 0.690
MOD_ProDKin_1 523 529 PF00069 0.510
MOD_ProDKin_1 553 559 PF00069 0.589
MOD_SUMO_rev_2 708 717 PF00179 0.458
TRG_DiLeu_BaEn_1 48 53 PF01217 0.615
TRG_DiLeu_BaEn_1 708 713 PF01217 0.465
TRG_ENDOCYTIC_2 138 141 PF00928 0.543
TRG_ENDOCYTIC_2 462 465 PF00928 0.489
TRG_ER_diArg_1 278 281 PF00400 0.632
TRG_ER_diArg_1 294 296 PF00400 0.546
TRG_ER_diArg_1 443 445 PF00400 0.684
TRG_ER_diArg_1 639 641 PF00400 0.568
TRG_ER_diArg_1 682 684 PF00400 0.531
TRG_NES_CRM1_1 305 315 PF08389 0.463
TRG_NES_CRM1_1 6 20 PF08389 0.464
TRG_Pf-PMV_PEXEL_1 266 271 PF00026 0.710
TRG_Pf-PMV_PEXEL_1 294 298 PF00026 0.595
TRG_Pf-PMV_PEXEL_1 444 449 PF00026 0.606
TRG_Pf-PMV_PEXEL_1 456 460 PF00026 0.482
TRG_Pf-PMV_PEXEL_1 684 688 PF00026 0.535

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8II80 Leishmania donovani 100% 100%
A4HMK8 Leishmania braziliensis 70% 100%
E9AF08 Leishmania major 90% 100%
E9B664 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS