Structural Proteins, Dynein-associated roadblock -like
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | yes | yes: 6 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 16 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 7 |
| NetGPI | no | yes: 0, no: 7 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005737 | cytoplasm | 2 | 4 |
| GO:0005815 | microtubule organizing center | 2 | 1 |
| GO:0005868 | cytoplasmic dynein complex | 4 | 4 |
| GO:0005875 | microtubule associated complex | 2 | 4 |
| GO:0005930 | axoneme | 2 | 1 |
| GO:0030286 | dynein complex | 3 | 4 |
| GO:0032991 | protein-containing complex | 1 | 4 |
| GO:0036064 | ciliary basal body | 3 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 4 |
| GO:1902494 | catalytic complex | 2 | 4 |
| GO:0005874 | microtubule | 6 | 3 |
| GO:0099080 | supramolecular complex | 2 | 3 |
| GO:0099081 | supramolecular polymer | 3 | 3 |
| GO:0099512 | supramolecular fiber | 4 | 3 |
| GO:0099513 | polymeric cytoskeletal fiber | 5 | 3 |
Related structures:
AlphaFold database: A4IB75
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0007017 | microtubule-based process | 2 | 4 |
| GO:0007018 | microtubule-based movement | 3 | 4 |
| GO:0009987 | cellular process | 1 | 4 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005488 | binding | 1 | 4 |
| GO:0005515 | protein binding | 2 | 4 |
| GO:0045505 | dynein intermediate chain binding | 3 | 4 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 19 | 21 | PF00675 | 0.485 |
| DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.418 |
| DOC_CYCLIN_yClb1_LxF_4 | 86 | 92 | PF00134 | 0.345 |
| DOC_MAPK_gen_1 | 95 | 103 | PF00069 | 0.345 |
| DOC_MAPK_MEF2A_6 | 107 | 114 | PF00069 | 0.345 |
| DOC_USP7_MATH_1 | 11 | 15 | PF00917 | 0.462 |
| DOC_USP7_MATH_1 | 51 | 55 | PF00917 | 0.345 |
| DOC_WW_Pin1_4 | 47 | 52 | PF00397 | 0.399 |
| LIG_14-3-3_CanoR_1 | 20 | 30 | PF00244 | 0.368 |
| LIG_14-3-3_CanoR_1 | 32 | 39 | PF00244 | 0.339 |
| LIG_14-3-3_CanoR_1 | 8 | 16 | PF00244 | 0.516 |
| LIG_FHA_1 | 38 | 44 | PF00498 | 0.376 |
| LIG_FHA_1 | 84 | 90 | PF00498 | 0.345 |
| LIG_FHA_2 | 53 | 59 | PF00498 | 0.345 |
| LIG_LIR_Gen_1 | 106 | 117 | PF02991 | 0.345 |
| LIG_LIR_Gen_1 | 28 | 37 | PF02991 | 0.328 |
| LIG_LIR_Nem_3 | 106 | 112 | PF02991 | 0.345 |
| LIG_LIR_Nem_3 | 28 | 33 | PF02991 | 0.328 |
| LIG_LIR_Nem_3 | 88 | 94 | PF02991 | 0.345 |
| LIG_SH2_STAP1 | 65 | 69 | PF00017 | 0.345 |
| LIG_SUMO_SIM_anti_2 | 108 | 114 | PF11976 | 0.345 |
| LIG_SUMO_SIM_anti_2 | 40 | 46 | PF11976 | 0.380 |
| LIG_SUMO_SIM_par_1 | 40 | 46 | PF11976 | 0.346 |
| LIG_UBA3_1 | 68 | 75 | PF00899 | 0.345 |
| MOD_CDK_SPxK_1 | 47 | 53 | PF00069 | 0.399 |
| MOD_CK1_1 | 15 | 21 | PF00069 | 0.541 |
| MOD_CK2_1 | 51 | 57 | PF00069 | 0.345 |
| MOD_GSK3_1 | 47 | 54 | PF00069 | 0.357 |
| MOD_GSK3_1 | 7 | 14 | PF00069 | 0.542 |
| MOD_N-GLC_1 | 37 | 42 | PF02516 | 0.380 |
| MOD_NEK2_1 | 16 | 21 | PF00069 | 0.537 |
| MOD_NEK2_1 | 68 | 73 | PF00069 | 0.399 |
| MOD_PIKK_1 | 31 | 37 | PF00454 | 0.345 |
| MOD_PKA_2 | 31 | 37 | PF00069 | 0.341 |
| MOD_PKA_2 | 52 | 58 | PF00069 | 0.323 |
| MOD_PKA_2 | 7 | 13 | PF00069 | 0.541 |
| MOD_Plk_1 | 56 | 62 | PF00069 | 0.399 |
| MOD_ProDKin_1 | 47 | 53 | PF00069 | 0.399 |
| TRG_ENDOCYTIC_2 | 65 | 68 | PF00928 | 0.345 |
| TRG_ER_diArg_1 | 92 | 95 | PF00400 | 0.345 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P8V1 | Leptomonas seymouri | 41% | 100% |
| A0A0N1HUN3 | Leptomonas seymouri | 95% | 100% |
| A0A0S4KIT1 | Bodo saltans | 84% | 100% |
| A0A1X0P773 | Trypanosomatidae | 48% | 100% |
| A0A3Q8IJB4 | Leishmania donovani | 100% | 100% |
| A0A3Q8IJQ7 | Leishmania donovani | 37% | 100% |
| A0A422P0L4 | Trypanosoma rangeli | 47% | 100% |
| A4H9K8 | Leishmania braziliensis | 35% | 100% |
| A4HMJ5 | Leishmania braziliensis | 96% | 100% |
| A4HXX4 | Leishmania infantum | 37% | 100% |
| C9ZMI4 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 30% | 100% |
| C9ZWI3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 30% | 100% |
| C9ZZS8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 45% | 100% |
| E9AEZ6 | Leishmania major | 97% | 100% |
| E9ARN8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 37% | 100% |
| E9B652 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 96% | 100% |
| P62627 | Mus musculus | 58% | 100% |
| P62628 | Rattus norvegicus | 58% | 100% |
| Q32P85 | Bos taurus | 56% | 100% |
| Q3T140 | Bos taurus | 58% | 100% |
| Q4QDU1 | Leishmania major | 37% | 100% |
| Q8TF09 | Homo sapiens | 56% | 100% |
| Q9DAJ5 | Mus musculus | 56% | 100% |
| Q9NP97 | Homo sapiens | 60% | 100% |
| V5BM74 | Trypanosoma cruzi | 48% | 100% |