PHD finger protein 10

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IB29_LEIIN

TriTrypDb:

LINF_350018500

Length:

449

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IB29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IB29

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	106	110	PF00656	0.579
CLV_C14_Caspase3-7	135	139	PF00656	0.645
CLV_C14_Caspase3-7	184	188	PF00656	0.668
CLV_C14_Caspase3-7	267	271	PF00656	0.750
CLV_C14_Caspase3-7	381	385	PF00656	0.481
CLV_NRD_NRD_1	29	31	PF00675	0.423
CLV_NRD_NRD_1	298	300	PF00675	0.604
CLV_NRD_NRD_1	387	389	PF00675	0.471
CLV_NRD_NRD_1	397	399	PF00675	0.418
CLV_NRD_NRD_1	417	419	PF00675	0.597
CLV_PCSK_FUR_1	426	430	PF00082	0.473
CLV_PCSK_FUR_1	445	449	PF00082	0.426
CLV_PCSK_KEX2_1	29	31	PF00082	0.423
CLV_PCSK_KEX2_1	298	300	PF00082	0.633
CLV_PCSK_KEX2_1	389	391	PF00082	0.502
CLV_PCSK_KEX2_1	396	398	PF00082	0.458
CLV_PCSK_KEX2_1	417	419	PF00082	0.504
CLV_PCSK_KEX2_1	428	430	PF00082	0.629
CLV_PCSK_KEX2_1	444	446	PF00082	0.423
CLV_PCSK_KEX2_1	447	449	PF00082	0.443
CLV_PCSK_PC1ET2_1	298	300	PF00082	0.615
CLV_PCSK_PC1ET2_1	389	391	PF00082	0.502
CLV_PCSK_PC1ET2_1	396	398	PF00082	0.458
CLV_PCSK_PC1ET2_1	428	430	PF00082	0.642
CLV_PCSK_PC1ET2_1	444	446	PF00082	0.421
CLV_PCSK_PC1ET2_1	447	449	PF00082	0.443
CLV_PCSK_PC7_1	392	398	PF00082	0.439
CLV_PCSK_SKI1_1	310	314	PF00082	0.655
CLV_PCSK_SKI1_1	397	401	PF00082	0.482
CLV_PCSK_SKI1_1	55	59	PF00082	0.646
DEG_Nend_UBRbox_3	1	3	PF02207	0.516
DEG_SCF_FBW7_1	361	367	PF00400	0.606
DEG_SCF_FBW7_2	84	89	PF00400	0.545
DEG_SPOP_SBC_1	201	205	PF00917	0.628
DOC_CKS1_1	245	250	PF01111	0.511
DOC_CKS1_1	361	366	PF01111	0.608
DOC_USP7_MATH_1	201	205	PF00917	0.648
DOC_USP7_MATH_1	226	230	PF00917	0.554
DOC_USP7_MATH_1	280	284	PF00917	0.650
DOC_USP7_MATH_1	294	298	PF00917	0.703
DOC_USP7_MATH_1	315	319	PF00917	0.694
DOC_USP7_MATH_1	336	340	PF00917	0.613
DOC_USP7_MATH_1	364	368	PF00917	0.641
DOC_USP7_UBL2_3	310	314	PF12436	0.698
DOC_USP7_UBL2_3	396	400	PF12436	0.477
DOC_USP7_UBL2_3	60	64	PF12436	0.588
DOC_WW_Pin1_4	112	117	PF00397	0.677
DOC_WW_Pin1_4	244	249	PF00397	0.498
DOC_WW_Pin1_4	257	262	PF00397	0.637
DOC_WW_Pin1_4	272	277	PF00397	0.560
DOC_WW_Pin1_4	298	303	PF00397	0.602
DOC_WW_Pin1_4	360	365	PF00397	0.644
DOC_WW_Pin1_4	82	87	PF00397	0.564
LIG_14-3-3_CanoR_1	19	24	PF00244	0.454
LIG_14-3-3_CanoR_1	365	371	PF00244	0.596
LIG_14-3-3_CanoR_1	42	50	PF00244	0.594
LIG_BIR_III_2	335	339	PF00653	0.588
LIG_eIF4E_1	323	329	PF01652	0.568
LIG_FHA_1	113	119	PF00498	0.642
LIG_FHA_1	258	264	PF00498	0.708
LIG_FHA_1	273	279	PF00498	0.586
LIG_FHA_1	319	325	PF00498	0.785
LIG_FHA_1	32	38	PF00498	0.476
LIG_FHA_2	104	110	PF00498	0.658
LIG_FHA_2	265	271	PF00498	0.758
LIG_FHA_2	341	347	PF00498	0.675
LIG_FHA_2	9	15	PF00498	0.444
LIG_LIR_Gen_1	376	385	PF02991	0.496
LIG_LIR_Nem_3	165	171	PF02991	0.529
LIG_LIR_Nem_3	177	182	PF02991	0.502
LIG_LIR_Nem_3	241	246	PF02991	0.529
LIG_LIR_Nem_3	376	382	PF02991	0.513
LIG_Pex14_2	58	62	PF04695	0.613
LIG_SH2_GRB2like	323	326	PF00017	0.623
LIG_SH2_STAT3	212	215	PF00017	0.568
LIG_SH2_STAT5	169	172	PF00017	0.496
LIG_SH2_STAT5	181	184	PF00017	0.583
LIG_SH2_STAT5	230	233	PF00017	0.485
LIG_SH2_STAT5	234	237	PF00017	0.475
LIG_SH2_STAT5	244	247	PF00017	0.497
LIG_SH2_STAT5	323	326	PF00017	0.623
LIG_SH2_STAT5	6	9	PF00017	0.438
LIG_SH3_3	188	194	PF00018	0.583
LIG_SH3_3	20	26	PF00018	0.498
LIG_SH3_3	309	315	PF00018	0.581
LIG_SH3_3	344	350	PF00018	0.668
LIG_SUMO_SIM_anti_2	375	384	PF11976	0.503
LIG_SUMO_SIM_par_1	123	129	PF11976	0.549
MOD_CDK_SPK_2	360	365	PF00069	0.609
MOD_CK1_1	126	132	PF00069	0.623
MOD_CK1_1	205	211	PF00069	0.587
MOD_CK1_1	318	324	PF00069	0.716
MOD_CK1_1	440	446	PF00069	0.494
MOD_CK1_1	48	54	PF00069	0.624
MOD_CK2_1	126	132	PF00069	0.579
MOD_CK2_1	221	227	PF00069	0.545
MOD_CK2_1	342	348	PF00069	0.626
MOD_GlcNHglycan	128	131	PF01048	0.637
MOD_GlcNHglycan	138	141	PF01048	0.643
MOD_GlcNHglycan	150	154	PF01048	0.642
MOD_GlcNHglycan	39	42	PF01048	0.652
MOD_GlcNHglycan	51	54	PF01048	0.520
MOD_GSK3_1	15	22	PF00069	0.480
MOD_GSK3_1	201	208	PF00069	0.698
MOD_GSK3_1	257	264	PF00069	0.714
MOD_GSK3_1	280	287	PF00069	0.646
MOD_GSK3_1	294	301	PF00069	0.593
MOD_GSK3_1	336	343	PF00069	0.637
MOD_GSK3_1	360	367	PF00069	0.613
MOD_GSK3_1	45	52	PF00069	0.584
MOD_GSK3_1	99	106	PF00069	0.667
MOD_LATS_1	47	53	PF00433	0.569
MOD_N-GLC_1	369	374	PF02516	0.493
MOD_N-GLC_2	393	395	PF02516	0.376
MOD_NEK2_1	1	6	PF00069	0.514
MOD_NEK2_1	185	190	PF00069	0.609
MOD_NEK2_1	37	42	PF00069	0.620
MOD_PIKK_1	202	208	PF00454	0.669
MOD_PIKK_1	211	217	PF00454	0.518
MOD_PIKK_1	261	267	PF00454	0.677
MOD_PK_1	19	25	PF00069	0.424
MOD_PKA_2	18	24	PF00069	0.454
MOD_PKA_2	318	324	PF00069	0.639
MOD_PKA_2	364	370	PF00069	0.601
MOD_PKA_2	43	49	PF00069	0.600
MOD_Plk_4	1	7	PF00069	0.473
MOD_Plk_4	175	181	PF00069	0.467
MOD_Plk_4	206	212	PF00069	0.568
MOD_Plk_4	226	232	PF00069	0.532
MOD_Plk_4	238	244	PF00069	0.438
MOD_Plk_4	336	342	PF00069	0.571
MOD_Plk_4	352	358	PF00069	0.517
MOD_Plk_4	437	443	PF00069	0.474
MOD_ProDKin_1	112	118	PF00069	0.675
MOD_ProDKin_1	244	250	PF00069	0.506
MOD_ProDKin_1	257	263	PF00069	0.639
MOD_ProDKin_1	272	278	PF00069	0.562
MOD_ProDKin_1	298	304	PF00069	0.600
MOD_ProDKin_1	360	366	PF00069	0.642
MOD_ProDKin_1	82	88	PF00069	0.564
MOD_SUMO_rev_2	381	391	PF00179	0.460
TRG_DiLeu_BaEn_3	377	383	PF01217	0.462
TRG_ENDOCYTIC_2	179	182	PF00928	0.539
TRG_ER_diArg_1	388	391	PF00400	0.497
TRG_ER_diArg_1	397	399	PF00400	0.442
TRG_NLS_Bipartite_1	428	448	PF00514	0.475
TRG_NLS_MonoCore_2	443	448	PF00514	0.518
TRG_NLS_MonoExtC_3	297	302	PF00514	0.607
TRG_NLS_MonoExtC_3	388	394	PF00514	0.442
TRG_NLS_MonoExtC_3	395	400	PF00514	0.404
TRG_NLS_MonoExtC_3	443	448	PF00514	0.518
TRG_NLS_MonoExtN_4	296	302	PF00514	0.609
TRG_NLS_MonoExtN_4	388	393	PF00514	0.447
TRG_Pf-PMV_PEXEL_1	397	401	PF00026	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5V5	Leptomonas seymouri	36%	88%
A0A3Q8IV47	Leishmania donovani	99%	100%
A4HMF8	Leishmania braziliensis	56%	100%
E9AEV9	Leishmania major	89%	100%
E9B615	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%