LeishMANIAdb
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Coiled-coil domain-containing protein 40

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Coiled-coil domain-containing protein 40
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IB18_LEIIN
TriTrypDb:
LINF_350017300
Length:
847

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IB18
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IB18

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 149 153 PF00656 0.606
CLV_C14_Caspase3-7 222 226 PF00656 0.489
CLV_NRD_NRD_1 133 135 PF00675 0.567
CLV_NRD_NRD_1 177 179 PF00675 0.428
CLV_NRD_NRD_1 244 246 PF00675 0.492
CLV_NRD_NRD_1 302 304 PF00675 0.554
CLV_NRD_NRD_1 316 318 PF00675 0.436
CLV_NRD_NRD_1 339 341 PF00675 0.512
CLV_NRD_NRD_1 401 403 PF00675 0.522
CLV_NRD_NRD_1 505 507 PF00675 0.545
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HX59 Leptomonas seymouri 52% 99%
A0A1X0NHD9 Trypanosomatidae 25% 100%
A0A3R7K5V9 Trypanosoma rangeli 27% 100%
A0A3S5H7Y8 Leishmania donovani 100% 100%
A4HME6 Leishmania braziliensis 78% 100%
C9ZNP9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 98%
E9AEU7 Leishmania major 93% 100%
E9B603 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS