LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Phosphorylation Abundance Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
cell cycle sequence binding phosphoprotein (RBP33) - putative
Species:
Leishmania infantum
UniProt:
A4IAZ2_LEIIN
TriTrypDb:
LINF_350014200
Length:
413

Annotations

Annotations by Jardim et al.

Cell Cycle, cell cycle sequence binding phospho (RBP33 Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1
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Phosphorylation

Amastigote: 159
Promastigote: 128
Promastigote/Amastigote: 22

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4IAZ2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAZ2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 149 153 PF00656 0.712
CLV_C14_Caspase3-7 159 163 PF00656 0.639
CLV_C14_Caspase3-7 180 184 PF00656 0.737
CLV_C14_Caspase3-7 379 383 PF00656 0.694
CLV_NRD_NRD_1 226 228 PF00675 0.409
CLV_NRD_NRD_1 259 261 PF00675 0.448
CLV_PCSK_KEX2_1 222 224 PF00082 0.448
CLV_PCSK_PC1ET2_1 222 224 PF00082 0.448
CLV_PCSK_SKI1_1 42 46 PF00082 0.620
DEG_COP1_1 119 129 PF00400 0.680
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I362 Leptomonas seymouri 68% 100%
A0A3Q8IEY4 Leishmania donovani 100% 100%
A4HMC6 Leishmania braziliensis 87% 99%
E9AES0 Leishmania major 98% 100%
E9B5X5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS