Putative actin-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

actin-like protein - putative

Species:

Leishmania infantum

UniProt:

A4IAX6_LEIIN

TriTrypDb:

LINF_350012600

Length:

519

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0043226	organelle	2	10
GO:0110165	cellular anatomical entity	1	10
GO:0000123	histone acetyltransferase complex	4	1
GO:0016514	SWI/SNF complex	4	1
GO:0031248	protein acetyltransferase complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0035267	NuA4 histone acetyltransferase complex	7	1
GO:0043189	H4/H2A histone acetyltransferase complex	6	1
GO:0070603	SWI/SNF superfamily-type complex	3	1
GO:0140513	nuclear protein-containing complex	2	1
GO:0140535	intracellular protein-containing complex	2	1
GO:1902493	acetyltransferase complex	4	1
GO:1902494	catalytic complex	2	1
GO:1902562	H4 histone acetyltransferase complex	5	1
GO:1904949	ATPase complex	3	1
GO:1990234	transferase complex	3	1

Expansion

Sequence features

A4IAX6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAX6

Function

Biological processes
Term	Name	Level	Count
GO:0006355	regulation of DNA-templated transcription	6	1
GO:0006357	regulation of transcription by RNA polymerase II	7	1
GO:0006473	protein acetylation	6	1
GO:0006475	internal protein amino acid acetylation	7	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0016570	histone modification	5	1
GO:0016573	histone acetylation	6	1
GO:0018193	peptidyl-amino acid modification	5	1
GO:0018205	peptidyl-lysine modification	6	1
GO:0018393	internal peptidyl-lysine acetylation	8	1
GO:0018394	peptidyl-lysine acetylation	7	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0019538	protein metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0036211	protein modification process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043412	macromolecule modification	4	1
GO:0043543	protein acylation	5	1
GO:0043967	histone H4 acetylation	7	1
GO:0044238	primary metabolic process	2	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1903506	regulation of nucleic acid-templated transcription	7	1
GO:2001141	regulation of RNA biosynthetic process	6	1

Molecular functions
Term	Name	Level	Count
GO:0003682	chromatin binding	2	1
GO:0005488	binding	1	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	214	218	PF00656	0.514
CLV_C14_Caspase3-7	372	376	PF00656	0.538
CLV_NRD_NRD_1	271	273	PF00675	0.309
CLV_NRD_NRD_1	515	517	PF00675	0.310
CLV_NRD_NRD_1	91	93	PF00675	0.277
CLV_PCSK_KEX2_1	271	273	PF00082	0.309
CLV_PCSK_KEX2_1	515	517	PF00082	0.275
CLV_PCSK_KEX2_1	91	93	PF00082	0.277
CLV_PCSK_SKI1_1	36	40	PF00082	0.317
CLV_PCSK_SKI1_1	515	519	PF00082	0.438
CLV_PCSK_SKI1_1	62	66	PF00082	0.232
CLV_PCSK_SKI1_1	92	96	PF00082	0.271
DEG_APCC_DBOX_1	158	166	PF00400	0.532
DEG_Nend_UBRbox_3	1	3	PF02207	0.736
DEG_SCF_FBW7_1	311	318	PF00400	0.565
DEG_SCF_FBW7_1	330	337	PF00400	0.412
DOC_CKS1_1	331	336	PF01111	0.412
DOC_CKS1_1	55	60	PF01111	0.532
DOC_CYCLIN_RxL_1	59	69	PF00134	0.435
DOC_CYCLIN_yCln2_LP_2	393	399	PF00134	0.492
DOC_CYCLIN_yCln2_LP_2	97	103	PF00134	0.492
DOC_MAPK_gen_1	159	167	PF00069	0.463
DOC_MAPK_gen_1	91	97	PF00069	0.477
DOC_MAPK_MEF2A_6	404	411	PF00069	0.540
DOC_PP4_FxxP_1	167	170	PF00568	0.541
DOC_PP4_FxxP_1	371	374	PF00568	0.572
DOC_USP7_MATH_1	128	132	PF00917	0.529
DOC_USP7_MATH_1	134	138	PF00917	0.500
DOC_USP7_MATH_1	152	156	PF00917	0.433
DOC_USP7_MATH_1	174	178	PF00917	0.742
DOC_USP7_MATH_1	21	25	PF00917	0.644
DOC_USP7_MATH_1	246	250	PF00917	0.540
DOC_USP7_MATH_1	307	311	PF00917	0.525
DOC_USP7_MATH_1	326	330	PF00917	0.555
DOC_USP7_MATH_1	332	336	PF00917	0.533
DOC_USP7_MATH_1	355	359	PF00917	0.534
DOC_USP7_MATH_1	361	365	PF00917	0.540
DOC_USP7_MATH_1	374	378	PF00917	0.363
DOC_USP7_MATH_1	387	391	PF00917	0.438
DOC_USP7_MATH_1	435	439	PF00917	0.573
DOC_USP7_MATH_1	67	71	PF00917	0.530
DOC_WW_Pin1_4	12	17	PF00397	0.699
DOC_WW_Pin1_4	148	153	PF00397	0.541
DOC_WW_Pin1_4	23	28	PF00397	0.301
DOC_WW_Pin1_4	311	316	PF00397	0.482
DOC_WW_Pin1_4	330	335	PF00397	0.541
DOC_WW_Pin1_4	362	367	PF00397	0.484
DOC_WW_Pin1_4	44	49	PF00397	0.520
DOC_WW_Pin1_4	54	59	PF00397	0.481
LIG_14-3-3_CanoR_1	135	139	PF00244	0.551
LIG_14-3-3_CanoR_1	20	30	PF00244	0.405
LIG_14-3-3_CanoR_1	271	275	PF00244	0.509
LIG_14-3-3_CanoR_1	468	474	PF00244	0.494
LIG_14-3-3_CterR_2	515	519	PF00244	0.612
LIG_Actin_WH2_2	104	120	PF00022	0.509
LIG_BRCT_BRCA1_1	367	371	PF00533	0.551
LIG_BRCT_BRCA1_1	437	441	PF00533	0.546
LIG_BRCT_BRCA1_1	67	71	PF00533	0.482
LIG_FHA_1	206	212	PF00498	0.467
LIG_FHA_1	24	30	PF00498	0.356
LIG_FHA_1	246	252	PF00498	0.458
LIG_FHA_1	281	287	PF00498	0.567
LIG_FHA_1	331	337	PF00498	0.541
LIG_FHA_1	45	51	PF00498	0.535
LIG_FHA_2	292	298	PF00498	0.538
LIG_FHA_2	370	376	PF00498	0.537
LIG_LIR_Apic_2	164	170	PF02991	0.541
LIG_LIR_Apic_2	227	232	PF02991	0.541
LIG_LIR_Apic_2	368	374	PF02991	0.574
LIG_LIR_Gen_1	143	154	PF02991	0.526
LIG_LIR_Gen_1	375	386	PF02991	0.544
LIG_LIR_Nem_3	143	149	PF02991	0.502
LIG_LIR_Nem_3	375	381	PF02991	0.545
LIG_LIR_Nem_3	391	397	PF02991	0.519
LIG_LYPXL_S_1	394	398	PF13949	0.341
LIG_LYPXL_yS_3	395	398	PF13949	0.541
LIG_MYND_1	48	52	PF01753	0.541
LIG_NRBOX	161	167	PF00104	0.509
LIG_NRBOX	250	256	PF00104	0.492
LIG_Pex14_2	441	445	PF04695	0.492
LIG_SH2_NCK_1	146	150	PF00017	0.541
LIG_SH2_PTP2	229	232	PF00017	0.565
LIG_SH2_STAP1	479	483	PF00017	0.565
LIG_SH2_STAT3	487	490	PF00017	0.565
LIG_SH2_STAT5	229	232	PF00017	0.568
LIG_SH2_STAT5	250	253	PF00017	0.462
LIG_SH2_STAT5	487	490	PF00017	0.565
LIG_SH2_STAT5	8	11	PF00017	0.746
LIG_SH3_3	146	152	PF00018	0.475
LIG_SH3_3	257	263	PF00018	0.541
LIG_SH3_3	328	334	PF00018	0.412
LIG_SH3_3	468	474	PF00018	0.494
LIG_SH3_3	52	58	PF00018	0.522
LIG_SUMO_SIM_par_1	211	217	PF11976	0.475
LIG_SUMO_SIM_par_1	29	35	PF11976	0.493
LIG_TRAF2_1	137	140	PF00917	0.509
LIG_TRAF2_1	170	173	PF00917	0.568
LIG_TRAF2_1	294	297	PF00917	0.541
LIG_TRAF2_1	504	507	PF00917	0.532
LIG_TYR_ITIM	144	149	PF00017	0.541
LIG_TYR_ITIM	393	398	PF00017	0.521
LIG_WRC_WIRS_1	491	496	PF05994	0.541
MOD_CDK_SPK_2	54	59	PF00069	0.541
MOD_CK1_1	12	18	PF00069	0.692
MOD_CK1_1	120	126	PF00069	0.483
MOD_CK1_1	249	255	PF00069	0.541
MOD_CK1_1	273	279	PF00069	0.472
MOD_CK1_1	318	324	PF00069	0.515
MOD_CK1_1	364	370	PF00069	0.528
MOD_CK1_1	493	499	PF00069	0.490
MOD_CK1_1	75	81	PF00069	0.572
MOD_CK2_1	134	140	PF00069	0.533
MOD_CK2_1	144	150	PF00069	0.515
MOD_CK2_1	291	297	PF00069	0.514
MOD_CK2_1	332	338	PF00069	0.517
MOD_CK2_1	374	380	PF00069	0.558
MOD_CK2_1	469	475	PF00069	0.570
MOD_GlcNHglycan	122	125	PF01048	0.276
MOD_GlcNHglycan	178	181	PF01048	0.694
MOD_GlcNHglycan	257	260	PF01048	0.339
MOD_GlcNHglycan	272	275	PF01048	0.344
MOD_GlcNHglycan	280	283	PF01048	0.332
MOD_GlcNHglycan	287	290	PF01048	0.206
MOD_GlcNHglycan	311	314	PF01048	0.332
MOD_GlcNHglycan	340	343	PF01048	0.355
MOD_GlcNHglycan	352	355	PF01048	0.363
MOD_GlcNHglycan	357	360	PF01048	0.345
MOD_GlcNHglycan	39	42	PF01048	0.290
MOD_GlcNHglycan	437	440	PF01048	0.285
MOD_GlcNHglycan	455	458	PF01048	0.376
MOD_GlcNHglycan	471	474	PF01048	0.307
MOD_GSK3_1	144	151	PF00069	0.541
MOD_GSK3_1	202	209	PF00069	0.485
MOD_GSK3_1	245	252	PF00069	0.534
MOD_GSK3_1	270	277	PF00069	0.498
MOD_GSK3_1	280	287	PF00069	0.496
MOD_GSK3_1	307	314	PF00069	0.556
MOD_GSK3_1	315	322	PF00069	0.527
MOD_GSK3_1	326	333	PF00069	0.521
MOD_GSK3_1	334	341	PF00069	0.512
MOD_GSK3_1	361	368	PF00069	0.494
MOD_GSK3_1	37	44	PF00069	0.482
MOD_GSK3_1	429	436	PF00069	0.464
MOD_GSK3_1	453	460	PF00069	0.551
MOD_GSK3_1	489	496	PF00069	0.478
MOD_GSK3_1	6	13	PF00069	0.723
MOD_GSK3_1	67	74	PF00069	0.509
MOD_GSK3_1	83	90	PF00069	0.554
MOD_N-GLC_1	461	466	PF02516	0.348
MOD_N-GLC_1	71	76	PF02516	0.309
MOD_NEK2_1	117	122	PF00069	0.497
MOD_NEK2_1	202	207	PF00069	0.492
MOD_NEK2_1	255	260	PF00069	0.541
MOD_NEK2_1	270	275	PF00069	0.541
MOD_NEK2_1	278	283	PF00069	0.508
MOD_NEK2_1	316	321	PF00069	0.528
MOD_NEK2_1	483	488	PF00069	0.487
MOD_NEK2_1	494	499	PF00069	0.463
MOD_NEK2_1	65	70	PF00069	0.483
MOD_NEK2_1	71	76	PF00069	0.495
MOD_NEK2_1	95	100	PF00069	0.509
MOD_NEK2_2	34	39	PF00069	0.475
MOD_PIKK_1	291	297	PF00454	0.565
MOD_PIKK_1	347	353	PF00454	0.537
MOD_PKA_2	117	123	PF00069	0.532
MOD_PKA_2	134	140	PF00069	0.551
MOD_PKA_2	270	276	PF00069	0.509
MOD_PKA_2	284	290	PF00069	0.412
MOD_PKA_2	453	459	PF00069	0.551
MOD_PKA_2	95	101	PF00069	0.546
MOD_Plk_1	326	332	PF00069	0.412
MOD_Plk_4	144	150	PF00069	0.509
MOD_Plk_4	246	252	PF00069	0.516
MOD_Plk_4	274	280	PF00069	0.544
MOD_Plk_4	326	332	PF00069	0.412
MOD_Plk_4	374	380	PF00069	0.509
MOD_Plk_4	483	489	PF00069	0.480
MOD_Plk_4	494	500	PF00069	0.466
MOD_ProDKin_1	12	18	PF00069	0.698
MOD_ProDKin_1	148	154	PF00069	0.541
MOD_ProDKin_1	23	29	PF00069	0.301
MOD_ProDKin_1	311	317	PF00069	0.482
MOD_ProDKin_1	330	336	PF00069	0.541
MOD_ProDKin_1	362	368	PF00069	0.484
MOD_ProDKin_1	44	50	PF00069	0.520
MOD_ProDKin_1	54	60	PF00069	0.481
TRG_DiLeu_BaLyEn_6	112	117	PF01217	0.509
TRG_DiLeu_BaLyEn_6	195	200	PF01217	0.475
TRG_DiLeu_BaLyEn_6	250	255	PF01217	0.475
TRG_ENDOCYTIC_2	146	149	PF00928	0.528
TRG_ENDOCYTIC_2	395	398	PF00928	0.504
TRG_ENDOCYTIC_2	443	446	PF00928	0.509
TRG_ER_diArg_1	159	162	PF00400	0.475
TRG_ER_diArg_1	270	272	PF00400	0.548
TRG_ER_diArg_1	515	517	PF00400	0.500
TRG_Pf-PMV_PEXEL_1	253	257	PF00026	0.292
TRG_Pf-PMV_PEXEL_1	62	66	PF00026	0.365

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2F8	Leptomonas seymouri	24%	100%
A0A0N0P696	Leptomonas seymouri	28%	100%
A0A0N0P8M2	Leptomonas seymouri	28%	100%
A0A0N1I0W8	Leptomonas seymouri	25%	100%
A0A0N1I659	Leptomonas seymouri	57%	100%
A0A0N1IM09	Leptomonas seymouri	28%	100%
A0A0S4IP23	Bodo saltans	23%	100%
A0A0S4ISP2	Bodo saltans	23%	100%
A0A0S4JB16	Bodo saltans	26%	100%
A0A0S4JGK8	Bodo saltans	24%	100%
A0A0S4JN99	Bodo saltans	26%	100%
A0A0S4JSR2	Bodo saltans	24%	100%
A0A1X0NIU0	Trypanosomatidae	26%	100%
A0A1X0NJ12	Trypanosomatidae	36%	100%
A0A1X0NKR1	Trypanosomatidae	25%	100%
A0A1X0NPN8	Trypanosomatidae	24%	100%
A0A1X0NRG7	Trypanosomatidae	25%	100%
A0A3Q8I9L1	Leishmania donovani	26%	100%
A0A3Q8IEK0	Leishmania donovani	28%	100%
A0A3Q8IJ53	Leishmania donovani	100%	100%
A0A3R7JX14	Trypanosoma rangeli	27%	100%
A0A3R7M5N2	Trypanosoma rangeli	25%	100%
A0A3S7WTM5	Leishmania donovani	26%	100%
A0A422MY22	Trypanosoma rangeli	24%	100%
A0A422NI92	Trypanosoma rangeli	39%	100%
A2BDB0	Xenopus laevis	25%	100%
A2XLF2	Oryza sativa subsp. indica	25%	100%
A2XNS1	Oryza sativa subsp. indica	25%	100%
A2YR10	Oryza sativa subsp. indica	22%	100%
A2YUL5	Oryza sativa subsp. indica	24%	100%
A3C6D7	Oryza sativa subsp. japonica	25%	100%
A4H783	Leishmania braziliensis	26%	92%
A4HA61	Leishmania braziliensis	26%	100%
A4HMB0	Leishmania braziliensis	80%	98%
A4HSC2	Leishmania infantum	24%	79%
A4HVM3	Leishmania infantum	26%	93%
A4HWL8	Leishmania infantum	26%	100%
A4HYD8	Leishmania infantum	28%	100%
A4IFE3	Bos taurus	27%	100%
A5DQP9	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	24%	100%
A7MB62	Bos taurus	24%	100%
C6KJC7	Leishmania donovani	24%	100%
C9ZYB5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
C9ZYB6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0A0S3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0LWX4	Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)	26%	100%
E9AKA4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	77%
E9APB9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	91%
E9AQC5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AS71	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ATB0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B5V9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
O00937	Sterkiella cavicola	23%	100%
O13419	Botryotinia fuckeliana	25%	100%
O15998	Ciona savignyi	25%	100%
O16808	Mayetiola destructor	25%	100%
O17320	Crassostrea gigas	24%	100%
O17502	Branchiostoma lanceolatum	25%	100%
O17503	Branchiostoma lanceolatum	25%	100%
O18499	Saccoglossus kowalevskii	25%	100%
O18500	Saccoglossus kowalevskii	24%	100%
O18840	Canis lupus familiaris	25%	100%
O42161	Salmo salar	25%	100%
O65314	Scherffelia dubia	25%	100%
O65315	Coleochaete scutata	25%	100%
O65316	Mesostigma viride	25%	100%
O74258	Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1)	25%	100%
O81221	Gossypium hirsutum	24%	100%
O93400	Xenopus laevis	25%	100%
O94630	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
O94805	Homo sapiens	24%	100%
O96621	Dictyostelium discoideum	23%	100%
P02572	Drosophila melanogaster	25%	100%
P02574	Drosophila melanogaster	25%	100%
P02576	Physarum polycephalum	25%	100%
P02578	Acanthamoeba castellanii	25%	100%
P02580	Glycine max	23%	100%
P02582	Zea mays	24%	100%
P02583	Oxytricha fallax	21%	100%
P04751	Xenopus laevis	25%	100%
P04752	Xenopus laevis	25%	100%
P04829	Bombyx mori	25%	100%
P07828	Dictyostelium discoideum	24%	100%
P07829	Dictyostelium discoideum	25%	100%
P07830	Dictyostelium discoideum	24%	100%
P07836	Bombyx mori	25%	100%
P07837	Bombyx mori	25%	100%
P08023	Gallus gallus	25%	100%
P0C539	Oryza sativa subsp. indica	25%	100%
P0C540	Oryza sativa subsp. japonica	25%	100%
P0C542	Oryza sativa subsp. indica	25%	100%
P0CJ46	Arabidopsis thaliana	24%	100%
P0CJ47	Arabidopsis thaliana	24%	100%
P0DM41	Caenorhabditis elegans	25%	100%
P0DM42	Caenorhabditis elegans	25%	100%
P10365	Thermomyces lanuginosus	25%	100%
P10981	Drosophila melanogaster	25%	100%
P10984	Caenorhabditis elegans	25%	100%
P10986	Caenorhabditis elegans	25%	100%
P10987	Drosophila melanogaster	25%	100%
P10988	Plasmodium falciparum (isolate NF54)	24%	100%
P10989	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
P10990	Mesocentrotus franciscanus	25%	100%
P10992	Tetrahymena thermophila	25%	100%
P10993	Tetrahymena pyriformis	25%	100%
P10995	Xenopus laevis	25%	100%
P11426	Entamoeba histolytica	26%	100%
P12431	Strongylocentrotus purpuratus	24%	100%
P12432	Trypanosoma brucei brucei	26%	100%
P12433	Trypanosoma brucei brucei	26%	100%
P12715	Sterkiella nova	23%	100%
P12716	Pisaster ochraceus	24%	100%
P12717	Pisaster ochraceus	24%	100%
P13363	Phytophthora megasperma	24%	100%
P14235	Candida albicans	24%	100%
P14883	Plasmodium falciparum (isolate NF54)	25%	100%
P15475	Xenopus borealis	25%	100%
P17126	Hydra vulgaris	24%	100%
P17128	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	100%
P17304	Aplysia californica	25%	100%
P18499	Strongylocentrotus purpuratus	24%	100%
P18600	Artemia sp.	26%	100%
P18601	Artemia sp.	25%	100%
P18603	Artemia sp.	25%	100%
P20359	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	25%	100%
P20360	Euplotes crassus	25%	100%
P20399	Xenopus tropicalis	25%	100%
P20904	Volvox carteri	25%	100%
P22131	Phytophthora infestans	25%	100%
P22132	Phytophthora infestans	25%	100%
P23343	Daucus carota	23%	100%
P24263	Physarum polycephalum	23%	100%
P26182	Achlya bisexualis	25%	100%
P26183	Cryptosporidium parvum	25%	100%
P26197	Absidia glauca	25%	100%
P26198	Styela clava	25%	100%
P27130	Halocynthia roretzi	25%	100%
P27131	Naegleria fowleri	25%	100%
P29751	Oryctolagus cuniculus	25%	100%
P30162	Onchocerca volvulus	25%	100%
P30163	Onchocerca volvulus	25%	100%
P30164	Pisum sativum	24%	100%
P30165	Pisum sativum	24%	100%
P30167	Solanum tuberosum	25%	100%
P30168	Solanum tuberosum	24%	100%
P30169	Solanum tuberosum	22%	100%
P30171	Solanum tuberosum	24%	100%
P30172	Solanum tuberosum	24%	100%
P30173	Solanum tuberosum	24%	100%
P32381	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P32390	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
P32392	Drosophila melanogaster	22%	100%
P35432	Echinococcus granulosus	25%	100%
P38673	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	27%	100%
P38696	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P41112	Podocoryna carnea	24%	100%
P41113	Podocoryna carnea	24%	100%
P41339	Limulus polyphemus	25%	100%
P41340	Limulus polyphemus	25%	100%
P41341	Limulus polyphemus	25%	100%
P42023	Pneumocystis carinii	28%	100%
P42025	Homo sapiens	28%	100%
P43239	Pneumocystis carinii	25%	100%
P45520	Leishmania major	23%	100%
P45885	Bactrocera dorsalis	25%	100%
P45886	Bactrocera dorsalis	25%	100%
P45887	Bactrocera dorsalis	25%	100%
P45888	Drosophila melanogaster	22%	100%
P45889	Drosophila melanogaster	26%	100%
P45891	Drosophila melanogaster	25%	100%
P46258	Pisum sativum	24%	100%
P48465	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	25%	100%
P48975	Cricetulus griseus	25%	100%
P49055	Carassius auratus	25%	100%
P49128	Aedes aegypti	26%	100%
P49871	Manduca sexta	25%	100%
P50138	Puccinia graminis	24%	100%
P51775	Giardia intestinalis	24%	100%
P53455	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	25%	100%
P53456	Dibothriocephalus dendriticus	25%	100%
P53457	Dibothriocephalus dendriticus	25%	100%
P53458	Dibothriocephalus dendriticus	25%	100%
P53459	Dibothriocephalus dendriticus	24%	100%
P53460	Halocynthia roretzi	25%	100%
P53461	Halocynthia roretzi	25%	100%
P53463	Heliocidaris erythrogramma	25%	100%
P53464	Heliocidaris tuberculata	25%	100%
P53465	Lytechinus pictus	25%	100%
P53466	Lytechinus pictus	24%	100%
P53467	Molgula oculata	25%	100%
P53468	Oxytricha trifallax	23%	100%
P53469	Oxytricha trifallax	24%	100%
P53470	Schistosoma mansoni	25%	100%
P53471	Schistosoma mansoni	25%	100%
P53472	Strongylocentrotus purpuratus	24%	100%
P53473	Strongylocentrotus purpuratus	24%	100%
P53474	Strongylocentrotus purpuratus	25%	100%
P53475	Styela clava	25%	100%
P53476	Toxoplasma gondii	26%	100%
P53477	Trypanosoma cruzi	25%	100%
P53478	Gallus gallus	25%	100%
P53479	Cyprinus carpio	25%	100%
P53480	Takifugu rubripes	25%	100%
P53482	Takifugu rubripes	25%	100%
P53483	Takifugu rubripes	24%	100%
P53485	Takifugu rubripes	25%	100%
P53486	Takifugu rubripes	25%	100%
P53487	Acanthamoeba castellanii	23%	100%
P53488	Gallus gallus	24%	100%
P53489	Caenorhabditis elegans	22%	100%
P53491	Acetabularia peniculus	24%	100%
P53492	Arabidopsis thaliana	24%	100%
P53494	Arabidopsis thaliana	25%	100%
P53496	Arabidopsis thaliana	25%	100%
P53497	Arabidopsis thaliana	25%	100%
P53498	Chlamydomonas reinhardtii	25%	100%
P53499	Chondrus crispus	25%	100%
P53500	Cyanidioschyzon merolae (strain NIES-3377 / 10D)	27%	100%
P53501	Drosophila melanogaster	25%	100%
P53502	Fucus distichus	26%	100%
P53503	Oxytricha fallax	21%	100%
P53504	Sorghum bicolor	24%	100%
P53505	Xenopus laevis	25%	100%
P53506	Xenopus laevis	25%	100%
P53689	Phaffia rhodozyma	25%	100%
P55805	Sterkiella nova	23%	100%
P60009	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	24%	100%
P60010	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P60011	Saccharomyces bayanus	24%	100%
P60706	Gallus gallus	25%	100%
P60707	Trichosurus vulpecula	25%	100%
P60708	Equus caballus	25%	100%
P60709	Homo sapiens	25%	100%
P60710	Mus musculus	25%	100%
P60711	Rattus norvegicus	25%	100%
P60712	Bos taurus	25%	100%
P60713	Ovis aries	25%	100%
P61160	Homo sapiens	24%	100%
P61161	Mus musculus	24%	100%
P61162	Canis lupus familiaris	26%	100%
P61163	Homo sapiens	26%	100%
P61164	Mus musculus	26%	100%
P62736	Homo sapiens	25%	100%
P62737	Mus musculus	25%	100%
P62738	Rattus norvegicus	25%	100%
P62739	Bos taurus	25%	100%
P62740	Oryctolagus cuniculus	25%	100%
P63256	Anser anser anser	25%	100%
P63257	Trichosurus vulpecula	25%	100%
P63258	Bos taurus	25%	100%
P63259	Rattus norvegicus	25%	100%
P63260	Mus musculus	25%	100%
P63261	Homo sapiens	25%	100%
P63267	Homo sapiens	25%	100%
P63268	Mus musculus	25%	100%
P63269	Rattus norvegicus	25%	100%
P63270	Gallus gallus	25%	100%
P68032	Homo sapiens	25%	100%
P68033	Mus musculus	25%	100%
P68034	Gallus gallus	25%	100%
P68035	Rattus norvegicus	25%	100%
P68133	Homo sapiens	25%	100%
P68134	Mus musculus	25%	100%
P68135	Oryctolagus cuniculus	25%	100%
P68136	Rattus norvegicus	25%	100%
P68137	Sus scrofa	25%	100%
P68138	Bos taurus	25%	100%
P68139	Gallus gallus	25%	100%
P68140	Takifugu rubripes	25%	100%
P68142	Takifugu rubripes	25%	100%
P68143	Oreochromis mossambicus	25%	100%
P68264	Oreochromis mossambicus	25%	100%
P68555	Taenia solium	25%	100%
P68556	Dibothriocephalus dendriticus	25%	100%
P69002	Heliocidaris erythrogramma	25%	100%
P69003	Heliocidaris tuberculata	25%	100%
P69004	Mesocentrotus franciscanus	25%	100%
P69005	Strongylocentrotus purpuratus	25%	100%
P78711	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	25%	100%
P79818	Oryzias latipes	25%	100%
P83750	Cyprinus carpio	25%	100%
P83751	Ctenopharyngodon idella	25%	100%
P83967	Drosophila melanogaster	25%	100%
P83968	Drosophila simulans	25%	100%
P83969	Bactrocera dorsalis	25%	100%
P84183	Bombyx mori	25%	100%
P84184	Helicoverpa armigera	25%	100%
P84185	Anopheles gambiae	25%	100%
P84336	Camelus dromedarius	24%	100%
P84856	Chlorocebus pygerythrus	24%	100%
P85515	Rattus norvegicus	26%	100%
P86287	Plasmodium falciparum (isolate HB3)	24%	100%
P86288	Plasmodium falciparum (isolate HB3)	26%	100%
P90689	Brugia malayi	25%	100%
P91754	Lumbricus rubellus	25%	100%
P92176	Lumbricus terrestris	24%	100%
P92179	Biomphalaria glabrata	24%	100%
P92182	Lumbricus terrestris	25%	100%
P93738	Arabidopsis thaliana	22%	100%
Q00214	Styela plicata	25%	100%
Q00215	Styela plicata	25%	100%
Q03341	Echinococcus granulosus	25%	100%
Q05214	Nicotiana tabacum	23%	100%
Q07903	Strongylocentrotus purpuratus	25%	100%
Q0PGG4	Bos mutus grunniens	25%	100%
Q10AZ4	Oryza sativa subsp. japonica	25%	100%
Q10DV7	Oryza sativa subsp. japonica	25%	100%
Q25010	Helicoverpa armigera	25%	100%
Q25472	Molgula oculata	25%	100%
Q26065	Placopecten magellanicus	25%	100%
Q2T9W4	Bos taurus	25%	100%
Q2TA43	Bos taurus	27%	100%
Q2U7A3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	25%	100%
Q32KZ2	Bos taurus	24%	100%
Q32L91	Bos taurus	24%	100%
Q39758	Fucus vesiculosus	25%	100%
Q3ZC07	Bos taurus	25%	100%
Q4FX37	Leishmania major	94%	100%
Q4L0Y2	Spermophilus citellus	25%	100%
Q4P2E8	Ustilago maydis (strain 521 / FGSC 9021)	21%	97%
Q4Q187	Leishmania major	26%	100%
Q4QD95	Leishmania major	27%	100%
Q4QF49	Leishmania major	26%	100%
Q4QG59	Leishmania major	26%	93%
Q4QR76	Rattus norvegicus	23%	100%
Q4R317	Macaca fascicularis	26%	100%
Q4R561	Macaca fascicularis	25%	100%
Q4R6J9	Macaca fascicularis	26%	100%
Q4R6Q3	Macaca fascicularis	24%	100%
Q4R821	Macaca fascicularis	24%	100%
Q4WHA3	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	23%	100%
Q4YU79	Plasmodium berghei (strain Anka)	26%	100%
Q4Z1L3	Plasmodium berghei (strain Anka)	24%	100%
Q54GX7	Dictyostelium discoideum	24%	100%
Q54HE7	Dictyostelium discoideum	24%	100%
Q54HE9	Dictyostelium discoideum	23%	100%
Q54HF0	Dictyostelium discoideum	24%	100%
Q54HF1	Dictyostelium discoideum	23%	100%
Q54I79	Dictyostelium discoideum	27%	100%
Q54L54	Dictyostelium discoideum	21%	100%
Q553U6	Dictyostelium discoideum	24%	100%
Q55CU2	Dictyostelium discoideum	21%	100%
Q55EU6	Dictyostelium discoideum	24%	100%
Q562R1	Homo sapiens	24%	100%
Q56A35	Danio rerio	24%	100%
Q5AW89	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	24%	100%
Q5BL41	Xenopus tropicalis	24%	100%
Q5E9B5	Bos taurus	25%	100%
Q5JAK2	Pelophylax lessonae	25%	100%
Q5M7U6	Rattus norvegicus	24%	100%
Q5R1X3	Pan troglodytes	25%	100%
Q5R4K0	Pongo abelii	23%	100%
Q5R6G0	Pongo abelii	25%	100%
Q5R9Q5	Pongo abelii	25%	100%
Q5XIK1	Rattus norvegicus	24%	100%
Q5ZMQ2	Gallus gallus	25%	100%
Q61JZ2	Caenorhabditis briggsae	21%	100%
Q641W9	Rattus norvegicus	24%	100%
Q6NVA9	Xenopus tropicalis	25%	100%
Q6P378	Xenopus tropicalis	25%	100%
Q6P640	Xenopus tropicalis	25%	100%
Q6P8G3	Xenopus tropicalis	25%	100%
Q6QAQ1	Sus scrofa	25%	100%
Q6TCF2	Gaeumannomyces avenae	25%	100%
Q6Z256	Oryza sativa subsp. japonica	24%	100%
Q6ZJW9	Oryza sativa subsp. japonica	22%	100%
Q711N9	Mesocricetus auratus	25%	100%
Q71FK5	Cavia porcellus	25%	100%
Q75D00	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	24%	100%
Q76N69	Chlorocebus aethiops	25%	100%
Q7RME1	Plasmodium yoelii yoelii	24%	100%
Q7RPB4	Plasmodium yoelii yoelii	26%	100%
Q7SXW6	Danio rerio	23%	100%
Q7ZTP2	Xenopus laevis	24%	100%
Q7ZVF9	Danio rerio	25%	100%
Q7ZVI7	Danio rerio	25%	100%
Q7ZXV3	Xenopus laevis	24%	100%
Q84M92	Arabidopsis thaliana	22%	100%
Q8BFZ3	Mus musculus	25%	100%
Q8BXF8	Mus musculus	23%	100%
Q8CG27	Mus musculus	24%	100%
Q8I4X0	Plasmodium falciparum (isolate 3D7)	24%	100%
Q8ILW9	Plasmodium falciparum (isolate 3D7)	26%	100%
Q8JJB8	Triakis scyllium	25%	100%
Q8R5C5	Mus musculus	27%	100%
Q8RYC2	Arabidopsis thaliana	26%	100%
Q8SWN8	Encephalitozoon cuniculi (strain GB-M1)	25%	100%
Q8TC94	Homo sapiens	23%	100%
Q8TDG2	Homo sapiens	24%	100%
Q8TDY3	Homo sapiens	25%	100%
Q8X119	Exophiala dermatitidis	25%	100%
Q90X97	Atractaspis microlepidota microlepidota	25%	100%
Q91ZK5	Sigmodon hispidus	25%	100%
Q93129	Branchiostoma belcheri	25%	100%
Q93130	Branchiostoma belcheri	25%	100%
Q93131	Branchiostoma floridae	25%	100%
Q93132	Branchiostoma floridae	26%	100%
Q95JK8	Macaca fascicularis	23%	100%
Q96292	Arabidopsis thaliana	24%	100%
Q96293	Arabidopsis thaliana	24%	100%
Q964D9	Planorbella trivolvis	24%	100%
Q964E0	Biomphalaria tenagophila	24%	100%
Q964E1	Biomphalaria obstructa	24%	100%
Q964E2	Biomphalaria pfeifferi	24%	100%
Q964E3	Biomphalaria alexandrina	24%	100%
Q98972	Oryzias latipes	25%	100%
Q99023	Hypocrea jecorina	23%	100%
Q9BYD9	Homo sapiens	21%	100%
Q9BYX7	Homo sapiens	24%	100%
Q9D9L5	Mus musculus	26%	100%
Q9LSD6	Arabidopsis thaliana	23%	100%
Q9NJV4	Naegleria pringsheimi	26%	100%
Q9P4D1	Komagataella phaffii (strain GS115 / ATCC 20864)	25%	100%
Q9P7X7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
Q9QY83	Mus musculus	23%	100%
Q9QY84	Mus musculus	25%	100%
Q9U1E8	Leishmania major	24%	79%
Q9URS0	Penicillium chrysogenum	25%	100%
Q9UUJ1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
Q9UVF3	Yarrowia lipolytica (strain CLIB 122 / E 150)	24%	100%
Q9UVW9	Acremonium chrysogenum	25%	100%
Q9UVX4	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	25%	100%
Q9UVZ8	Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)	24%	100%
Q9Y614	Homo sapiens	23%	100%
Q9Y615	Homo sapiens	25%	100%
Q9Y701	Suillus bovinus	25%	100%
Q9Y702	Schizophyllum commune	25%	100%
Q9Y707	Suillus bovinus	25%	100%
Q9Y896	Schizophyllum commune	26%	100%
V5AW65	Trypanosoma cruzi	26%	100%
V5AZ19	Trypanosoma cruzi	22%	100%
V5BDL0	Trypanosoma cruzi	25%	100%
V5BWS6	Trypanosoma cruzi	25%	100%
V5C0Q2	Trypanosoma cruzi	26%	100%
V5DJL3	Trypanosoma cruzi	36%	100%