LeishMANIAdb
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Peptidase_S9 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Peptidase_S9 domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IAS9_LEIIN
TriTrypDb:
LINF_350007900
Length:
135

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IAS9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAS9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 46 48 PF00082 0.538
CLV_PCSK_PC1ET2_1 46 48 PF00082 0.538
CLV_PCSK_SKI1_1 128 132 PF00082 0.544
CLV_PCSK_SKI1_1 77 81 PF00082 0.555
DEG_Nend_UBRbox_1 1 4 PF02207 0.688
DOC_CKS1_1 90 95 PF01111 0.555
DOC_MAPK_DCC_7 50 60 PF00069 0.542
DOC_MAPK_gen_1 109 118 PF00069 0.530
DOC_MAPK_gen_1 46 57 PF00069 0.546
DOC_MAPK_MEF2A_6 46 55 PF00069 0.625
DOC_PP2B_LxvP_1 24 27 PF13499 0.588
DOC_USP7_MATH_1 15 19 PF00917 0.543
DOC_USP7_MATH_1 61 65 PF00917 0.604
DOC_WW_Pin1_4 89 94 PF00397 0.552
LIG_Actin_WH2_2 115 133 PF00022 0.528
LIG_FHA_1 117 123 PF00498 0.520
LIG_LIR_Gen_1 113 123 PF02991 0.515
LIG_LIR_LC3C_4 22 26 PF02991 0.592
LIG_LIR_Nem_3 113 118 PF02991 0.510
LIG_NRBOX 6 12 PF00104 0.587
LIG_PDZ_Class_1 130 135 PF00595 0.589
LIG_Pex14_2 114 118 PF04695 0.512
LIG_SH2_STAT5 117 120 PF00017 0.516
LIG_SH2_STAT5 31 34 PF00017 0.496
LIG_SH3_3 50 56 PF00018 0.488
LIG_SH3_3 87 93 PF00018 0.542
MOD_GlcNHglycan 6 10 PF01048 0.555
MOD_GlcNHglycan 94 97 PF01048 0.575
MOD_GSK3_1 61 68 PF00069 0.628
MOD_GSK3_1 92 99 PF00069 0.569
MOD_N-GLC_1 15 20 PF02516 0.618
MOD_NEK2_1 130 135 PF00069 0.589
MOD_Plk_1 5 11 PF00069 0.556
MOD_Plk_4 34 40 PF00069 0.518
MOD_ProDKin_1 89 95 PF00069 0.552
TRG_DiLeu_BaEn_1 6 11 PF01217 0.632
TRG_ENDOCYTIC_2 117 120 PF00928 0.516
TRG_ER_diArg_1 108 111 PF00400 0.567
TRG_Pf-PMV_PEXEL_1 128 132 PF00026 0.544

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X8R6 Leishmania donovani 99% 100%
E9AEK5 Leishmania major 78% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS