Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IAS8_LEIIN

TriTrypDb:

LINF_350007800

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

A4IAS8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAS8


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_Nbox_1	1	3	PF02207	0.652
DOC_USP7_MATH_1	45	49	PF00917	0.501
DOC_USP7_MATH_1	68	72	PF00917	0.622
LIG_Actin_WH2_2	49	67	PF00022	0.430
LIG_FHA_1	17	23	PF00498	0.355
LIG_HP1_1	53	57	PF01393	0.287
LIG_LIR_Gen_1	19	28	PF02991	0.546
LIG_LIR_Nem_3	19	23	PF02991	0.355
LIG_LIR_Nem_3	4	10	PF02991	0.556
LIG_Pex14_2	7	11	PF04695	0.410
LIG_SUMO_SIM_par_1	13	19	PF11976	0.390
LIG_SUMO_SIM_par_1	27	33	PF11976	0.378
LIG_WRC_WIRS_1	17	22	PF05994	0.376
MOD_CK1_1	16	22	PF00069	0.430
MOD_GlcNHglycan	47	50	PF01048	0.501
MOD_GlcNHglycan	72	75	PF01048	0.471
MOD_GSK3_1	68	75	PF00069	0.628
MOD_NEK2_1	1	6	PF00069	0.675
MOD_NEK2_1	13	18	PF00069	0.430
MOD_Plk_4	13	19	PF00069	0.379


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P608	Leptomonas seymouri	64%	100%
A0A3Q8IIN9	Leishmania donovani	100%	100%
A4HM66	Leishmania braziliensis	79%	100%
D0A2D0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	97%
E9AEK4	Leishmania major	90%	100%
E9B5R5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%