LeishMANIAdb
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60S ribosomal protein L30

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
60S ribosomal protein L30
Gene product:
60S ribosomal protein L30
Species:
Leishmania infantum
UniProt:
A4IAS5_LEIIN
TriTrypDb:
LINF_350007500
Length:
104

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S ribosomal L30

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 25
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 24
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 5
GO:0032991 protein-containing complex 1 12
GO:0043226 organelle 2 5
GO:0043228 non-membrane-bounded organelle 3 5
GO:0043229 intracellular organelle 3 5
GO:0043232 intracellular non-membrane-bounded organelle 4 5
GO:0110165 cellular anatomical entity 1 5
GO:1990904 ribonucleoprotein complex 2 12
GO:0015934 large ribosomal subunit 4 7
GO:0022625 cytosolic large ribosomal subunit 5 7
GO:0044391 ribosomal subunit 3 7

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4IAS5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAS5

PDB structure(s): 6az3_d

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 12
GO:0003723 RNA binding 4 12
GO:0005488 binding 1 12
GO:0097159 organic cyclic compound binding 2 12
GO:1901363 heterocyclic compound binding 2 12
GO:0003735 structural constituent of ribosome 2 7
GO:0005198 structural molecule activity 1 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 54 56 PF00675 0.193
CLV_PCSK_KEX2_1 54 56 PF00082 0.293
CLV_PCSK_SKI1_1 24 28 PF00082 0.190
DEG_APCC_DBOX_1 39 47 PF00400 0.390
DOC_MAPK_gen_1 37 46 PF00069 0.390
DOC_MAPK_gen_1 85 94 PF00069 0.390
DOC_USP7_UBL2_3 4 8 PF12436 0.430
DOC_WW_Pin1_4 64 69 PF00397 0.397
LIG_BIR_II_1 1 5 PF00653 0.470
LIG_FHA_1 87 93 PF00498 0.457
LIG_LIR_Gen_1 59 69 PF02991 0.390
LIG_LIR_Nem_3 59 64 PF02991 0.390
LIG_PDZ_Class_2 99 104 PF00595 0.493
LIG_SH2_CRK 61 65 PF00017 0.390
LIG_SH2_STAT5 25 28 PF00017 0.390
LIG_SH2_STAT5 61 64 PF00017 0.403
LIG_SUMO_SIM_anti_2 41 47 PF11976 0.390
LIG_SUMO_SIM_par_1 41 47 PF11976 0.394
LIG_SUMO_SIM_par_1 89 95 PF11976 0.391
MOD_GlcNHglycan 21 24 PF01048 0.190
MOD_GlcNHglycan 72 75 PF01048 0.235
MOD_GSK3_1 4 11 PF00069 0.411
MOD_GSK3_1 60 67 PF00069 0.425
MOD_GSK3_1 86 93 PF00069 0.443
MOD_N-GLC_2 48 50 PF02516 0.257
MOD_NEK2_1 92 97 PF00069 0.510
MOD_NEK2_2 32 37 PF00069 0.434
MOD_OFUCOSY 83 90 PF10250 0.233
MOD_PIKK_1 26 32 PF00454 0.433
MOD_ProDKin_1 64 70 PF00069 0.397
TRG_ENDOCYTIC_2 61 64 PF00928 0.391
TRG_ER_diArg_1 53 55 PF00400 0.493

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PD37 Leptomonas seymouri 94% 100%
A0A0S4J4N7 Bodo saltans 82% 99%
A0A1D8PM75 Candida albicans (strain SC5314 / ATCC MYA-2876) 49% 98%
A0A1X0NJL1 Trypanosomatidae 81% 99%
A0A3Q8IET6 Leishmania donovani 100% 100%
A0A3R7NIB1 Trypanosoma rangeli 83% 99%
A0B560 Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) 34% 100%
A1RSE6 Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) 30% 100%
A3MXZ2 Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) 32% 100%
A4FWF4 Methanococcus maripaludis (strain C5 / ATCC BAA-1333) 32% 98%
A4HM63 Leishmania braziliensis 94% 100%
A5ULN4 Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS) 32% 100%
A6VGV1 Methanococcus maripaludis (strain C7 / ATCC BAA-1331) 34% 98%
A7I9N4 Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8) 34% 100%
A8MB78 Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167) 32% 100%
A9A9U8 Methanococcus maripaludis (strain C6 / ATCC BAA-1332) 34% 98%
B1YC27 Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta) 29% 100%
B8GDW0 Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) 33% 100%
C5A206 Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) 30% 100%
C6A1G2 Thermococcus sibiricus (strain DSM 12597 / MM 739) 31% 100%
D0A2D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 86% 99%
D0A2D3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 86% 91%
E9AEK1 Leishmania major 98% 100%
E9B5R2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 100% 100%
O27127 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 32% 100%
O28389 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) 32% 100%
O48558 Zea mays 63% 93%
O49884 Lupinus luteus 59% 93%
O74018 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 31% 100%
P0DJ59 Tetrahymena thermophila (strain SB210) 49% 100%
P11522 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) 32% 100%
P14025 Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) 35% 99%
P14120 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 54% 99%
P29160 Thermococcus celer 31% 100%
P38664 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 52% 99%
P39095 Leishmania major 96% 100%
P49153 Trypanosoma brucei brucei 86% 99%
P52808 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 64% 95%
P54061 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 32% 95%
P58372 Ictalurus punctatus 60% 90%
P58374 Branchiostoma belcheri 60% 91%
P58375 Spodoptera frugiperda 60% 92%
P58376 Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) 26% 98%
P62888 Homo sapiens 60% 90%
P62889 Mus musculus 60% 90%
P62890 Rattus norvegicus 60% 90%
P67883 Gallus gallus 60% 90%
P67884 Ophiophagus hannah 60% 90%
Q2FPJ8 Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) 35% 100%
Q2NEK6 Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) 32% 100%
Q3T0D5 Bos taurus 60% 90%
Q55BS9 Dictyostelium discoideum 59% 93%
Q5I7K9 Triticum aestivum 56% 93%
Q5JE35 Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) 31% 100%
Q6C4U7 Yarrowia lipolytica (strain CLIB 122 / E 150) 48% 95%
Q6FXZ0 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 54% 99%
Q6LXI6 Methanococcus maripaludis (strain S2 / LL) 34% 100%
Q752U5 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 53% 99%
Q76KA2 Macaca fascicularis 60% 90%
Q7S7F1 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 56% 95%
Q8PUR3 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) 29% 100%
Q8TRB9 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) 29% 100%
Q8TXJ0 Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) 33% 95%
Q8U0M6 Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) 33% 100%
Q8VZ19 Arabidopsis thaliana 60% 93%
Q8ZYQ6 Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) 33% 100%
Q980R3 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) 28% 96%
Q9C8F7 Arabidopsis thaliana 59% 93%
Q9LSA3 Arabidopsis thaliana 58% 93%
Q9M5M6 Euphorbia esula 59% 93%
Q9SDG6 Oryza sativa subsp. japonica 63% 94%
Q9UTP0 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 62% 89%
Q9V112 Pyrococcus abyssi (strain GE5 / Orsay) 31% 100%
Q9YAU3 Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) 36% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS