LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4IAN5_LEIIN
TriTrypDb:
LINF_340038400
Length:
425

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 7
GO:0110165 cellular anatomical entity 1 7
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Expansion

Sequence features

A4IAN5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAN5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 365 369 PF00656 0.452
CLV_NRD_NRD_1 12 14 PF00675 0.723
CLV_NRD_NRD_1 304 306 PF00675 0.740
CLV_PCSK_KEX2_1 12 14 PF00082 0.703
CLV_PCSK_KEX2_1 145 147 PF00082 0.726
CLV_PCSK_KEX2_1 306 308 PF00082 0.697
CLV_PCSK_PC1ET2_1 145 147 PF00082 0.726
CLV_PCSK_PC1ET2_1 306 308 PF00082 0.565
CLV_PCSK_SKI1_1 168 172 PF00082 0.720
CLV_PCSK_SKI1_1 226 230 PF00082 0.645
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IHK0 Leptomonas seymouri 47% 96%
A0A3R7MRN0 Trypanosoma rangeli 21% 100%
A0A3S7X898 Leishmania donovani 99% 100%
A4HB34 Leishmania braziliensis 70% 100%
E9B5A4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4Q2M9 Leishmania major 86% 100%
V5BQG2 Trypanosoma cruzi 23% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS