LeishMANIAdb
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WD_REPEATS_REGION domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
WD_REPEATS_REGION domain-containing protein
Gene product:
WD domain - G-beta repeat - putative
Species:
Leishmania infantum
UniProt:
A4IAL0_LEIIN
TriTrypDb:
LINF_340052000
Length:
325

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 14
NetGPI no yes: 0, no: 14
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IAL0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAL0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 303 307 PF00656 0.342
CLV_NRD_NRD_1 101 103 PF00675 0.414
CLV_PCSK_KEX2_1 101 103 PF00082 0.548
CLV_PCSK_SKI1_1 123 127 PF00082 0.380
CLV_PCSK_SKI1_1 169 173 PF00082 0.424
CLV_PCSK_SKI1_1 292 296 PF00082 0.376
CLV_PCSK_SKI1_1 56 60 PF00082 0.531
DOC_CKS1_1 213 218 PF01111 0.513
DOC_MAPK_gen_1 194 202 PF00069 0.381
DOC_MAPK_HePTP_8 311 323 PF00069 0.455
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IGS3 Leptomonas seymouri 57% 100%
A0A0S4IHW1 Bodo saltans 27% 84%
A0A0S4IPM9 Bodo saltans 36% 96%
A0A0S4IXK3 Bodo saltans 28% 87%
A0A0S4JA66 Bodo saltans 25% 99%
A0A1X0PB94 Trypanosomatidae 37% 96%
A0A3R7RJK1 Trypanosoma rangeli 37% 97%
A0A3S7X8N9 Leishmania donovani 99% 100%
A4HBG4 Leishmania braziliensis 74% 100%
C9ZLN0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS