LeishMANIAdb
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Gene product:
NADH-ubiquinone oxidoreductase complex I subunit - putative
Species:
Leishmania infantum
UniProt:
A4IAK3_LEIIN
TriTrypDb:
LINF_340051000
Length:
112

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
GO:0005747 mitochondrial respiratory chain complex I 4 1
GO:0030964 NADH dehydrogenase complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0045271 respiratory chain complex I 4 1
GO:0098796 membrane protein complex 2 1
GO:0098798 mitochondrial protein-containing complex 2 1
GO:0098800 inner mitochondrial membrane protein complex 3 1
GO:0098803 respiratory chain complex 3 1
GO:1902494 catalytic complex 2 1
GO:1902495 transmembrane transporter complex 3 1
GO:1990204 oxidoreductase complex 3 1
GO:1990351 transporter complex 2 1

Expansion

Sequence features

A4IAK3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAK3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 14 16 PF00675 0.590
CLV_NRD_NRD_1 19 21 PF00675 0.607
CLV_NRD_NRD_1 84 86 PF00675 0.278
CLV_NRD_NRD_1 89 91 PF00675 0.272
CLV_PCSK_FUR_1 87 91 PF00082 0.288
CLV_PCSK_KEX2_1 14 16 PF00082 0.589
CLV_PCSK_KEX2_1 19 21 PF00082 0.609
CLV_PCSK_KEX2_1 84 86 PF00082 0.278
CLV_PCSK_KEX2_1 89 91 PF00082 0.273
CLV_PCSK_PC7_1 15 21 PF00082 0.615
CLV_PCSK_PC7_1 85 91 PF00082 0.275
CLV_PCSK_SKI1_1 7 11 PF00082 0.595
DEG_SCF_FBW7_1 30 36 PF00400 0.422
DOC_CKS1_1 30 35 PF01111 0.426
DOC_MAPK_gen_1 87 97 PF00069 0.488
DOC_MAPK_MEF2A_6 49 57 PF00069 0.343
DOC_PP1_RVXF_1 17 24 PF00149 0.423
DOC_WW_Pin1_4 29 34 PF00397 0.431
LIG_14-3-3_CanoR_1 34 38 PF00244 0.303
LIG_Clathr_ClatBox_1 95 99 PF01394 0.488
LIG_deltaCOP1_diTrp_1 42 51 PF00928 0.290
LIG_LIR_Nem_3 16 21 PF02991 0.417
LIG_NRP_CendR_1 111 112 PF00754 0.406
LIG_Pex14_2 37 41 PF04695 0.290
LIG_SH2_CRK 68 72 PF00017 0.507
LIG_SH2_STAT5 31 34 PF00017 0.433
LIG_SH3_3 27 33 PF00018 0.433
LIG_SUMO_SIM_anti_2 94 99 PF11976 0.488
LIG_TRAF2_1 78 81 PF00917 0.490
MOD_CDK_SPK_2 29 34 PF00069 0.448
MOD_CMANNOS 41 44 PF00535 0.490
MOD_GSK3_1 29 36 PF00069 0.422
MOD_GSK3_1 66 73 PF00069 0.348
MOD_NEK2_1 13 18 PF00069 0.412
MOD_NEK2_2 33 38 PF00069 0.290
MOD_PKA_2 13 19 PF00069 0.410
MOD_PKA_2 33 39 PF00069 0.307
MOD_ProDKin_1 29 35 PF00069 0.425
TRG_DiLeu_BaEn_1 91 96 PF01217 0.488
TRG_ENDOCYTIC_2 68 71 PF00928 0.507
TRG_ER_diArg_1 13 15 PF00400 0.396
TRG_ER_diArg_1 18 20 PF00400 0.405
TRG_ER_diArg_1 83 85 PF00400 0.479
TRG_ER_diArg_1 86 89 PF00400 0.475

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2D2 Leptomonas seymouri 94% 100%
A0A0S4IKM0 Bodo saltans 79% 100%
A0A1X0PB38 Trypanosomatidae 89% 100%
A0A3Q8IFX1 Leishmania donovani 100% 100%
A4HBF4 Leishmania braziliensis 99% 100%
C9ZLN8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 88% 100%
E9B5M7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4Q291 Leishmania major 98% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS