Dynein light chain roadblock

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IAJ4_LEIIN

TriTrypDb:

LINF_340050100

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

A4IAJ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAJ4


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	77	81	PF00656	0.537
CLV_PCSK_KEX2_1	62	64	PF00082	0.415
CLV_PCSK_KEX2_1	90	92	PF00082	0.416
CLV_PCSK_PC1ET2_1	62	64	PF00082	0.434
CLV_PCSK_PC1ET2_1	90	92	PF00082	0.416
CLV_PCSK_SKI1_1	40	44	PF00082	0.397
CLV_PCSK_SKI1_1	62	66	PF00082	0.448
DEG_SPOP_SBC_1	21	25	PF00917	0.463
DOC_MAPK_gen_1	62	68	PF00069	0.405
LIG_14-3-3_CanoR_1	63	67	PF00244	0.402
LIG_BIR_II_1	1	5	PF00653	0.471
LIG_BRCT_BRCA1_1	31	35	PF00533	0.383
LIG_BRCT_BRCA1_1	51	55	PF00533	0.537
LIG_BRCT_BRCA1_2	51	57	PF00533	0.390
LIG_FHA_2	75	81	PF00498	0.444
LIG_LIR_Gen_1	65	75	PF02991	0.396
LIG_LIR_Nem_3	65	71	PF02991	0.416
LIG_SH2_CRK	45	49	PF00017	0.448
LIG_SH2_CRK	85	89	PF00017	0.481
LIG_SH2_NCK_1	45	49	PF00017	0.359
LIG_SH2_SRC	45	48	PF00017	0.389
LIG_SH2_STAT5	73	76	PF00017	0.345
LIG_SUMO_SIM_anti_2	2	9	PF11976	0.518
LIG_TYR_ITIM	43	48	PF00017	0.444
MOD_CK1_1	2	8	PF00069	0.447
MOD_GlcNHglycan	24	27	PF01048	0.434
MOD_GlcNHglycan	30	34	PF01048	0.367
MOD_GlcNHglycan	51	54	PF01048	0.443
MOD_GlcNHglycan	80	83	PF01048	0.520
MOD_GSK3_1	74	81	PF00069	0.414
MOD_GSK3_1	90	97	PF00069	0.615
MOD_NEK2_1	22	27	PF00069	0.514
MOD_PKA_1	62	68	PF00069	0.410
MOD_PKA_1	90	96	PF00069	0.599
MOD_PKA_2	62	68	PF00069	0.410
MOD_PKA_2	90	96	PF00069	0.599
MOD_Plk_4	2	8	PF00069	0.447
MOD_SUMO_for_1	56	59	PF00179	0.602
TRG_ENDOCYTIC_2	45	48	PF00928	0.412
TRG_ENDOCYTIC_2	85	88	PF00928	0.475


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE77	Leptomonas seymouri	82%	100%
A0A0S4KJ18	Bodo saltans	47%	100%
A0A1X0PB28	Trypanosomatidae	52%	98%
A0A3R7MX32	Trypanosoma rangeli	57%	98%
A0A3S7X8J4	Leishmania donovani	100%	100%
A4HBE6	Leishmania braziliensis	90%	100%
C9ZLP6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	68%