Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IAJ1_LEIIN

TriTrypDb:

LINF_340049800

Length:

221

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IAJ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAJ1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.586
CLV_NRD_NRD_1	71	73	PF00675	0.524
CLV_PCSK_KEX2_1	71	73	PF00082	0.626
CLV_PCSK_SKI1_1	115	119	PF00082	0.476
CLV_PCSK_SKI1_1	193	197	PF00082	0.571
DEG_APCC_DBOX_1	113	121	PF00400	0.579
DEG_SCF_FBW7_1	211	217	PF00400	0.647
DOC_CKS1_1	211	216	PF01111	0.640
DOC_CYCLIN_RxL_1	111	122	PF00134	0.577
DOC_MAPK_gen_1	191	200	PF00069	0.587
DOC_MAPK_gen_1	26	34	PF00069	0.454
DOC_MAPK_MEF2A_6	193	202	PF00069	0.590
DOC_PP1_RVXF_1	113	120	PF00149	0.582
DOC_USP7_MATH_1	138	142	PF00917	0.586
DOC_USP7_MATH_1	214	218	PF00917	0.751
DOC_USP7_MATH_1	35	39	PF00917	0.614
DOC_USP7_MATH_1	99	103	PF00917	0.563
DOC_USP7_MATH_2	164	170	PF00917	0.554
DOC_WW_Pin1_4	127	132	PF00397	0.473
DOC_WW_Pin1_4	160	165	PF00397	0.525
DOC_WW_Pin1_4	207	212	PF00397	0.687
LIG_14-3-3_CanoR_1	177	187	PF00244	0.518
LIG_14-3-3_CanoR_1	193	202	PF00244	0.477
LIG_deltaCOP1_diTrp_1	149	154	PF00928	0.586
LIG_FHA_2	183	189	PF00498	0.636
LIG_LIR_Gen_1	165	176	PF02991	0.591
LIG_LIR_Nem_3	122	127	PF02991	0.551
LIG_LIR_Nem_3	165	171	PF02991	0.581
LIG_PDZ_Class_2	216	221	PF00595	0.677
LIG_Pex14_1	150	154	PF04695	0.589
LIG_Pex14_2	146	150	PF04695	0.536
LIG_Pex14_2	154	158	PF04695	0.596
LIG_Pex14_2	40	44	PF04695	0.613
LIG_PTB_Apo_2	7	14	PF02174	0.510
LIG_SH2_CRK	136	140	PF00017	0.582
LIG_SH2_STAT5	116	119	PF00017	0.577
LIG_SH2_STAT5	124	127	PF00017	0.442
LIG_SH2_STAT5	57	60	PF00017	0.523
LIG_SH3_2	21	26	PF14604	0.467
LIG_SH3_3	128	134	PF00018	0.481
LIG_SH3_3	18	24	PF00018	0.593
LIG_SH3_3	208	214	PF00018	0.697
MOD_CK1_1	210	216	PF00069	0.632
MOD_CK2_1	1	7	PF00069	0.591
MOD_CK2_1	160	166	PF00069	0.525
MOD_GlcNHglycan	101	104	PF01048	0.554
MOD_GSK3_1	166	173	PF00069	0.577
MOD_GSK3_1	178	185	PF00069	0.500
MOD_GSK3_1	210	217	PF00069	0.609
MOD_N-GLC_2	98	100	PF02516	0.366
MOD_NEK2_1	139	144	PF00069	0.591
MOD_NEK2_1	47	52	PF00069	0.506
MOD_NEK2_2	35	40	PF00069	0.555
MOD_PIKK_1	214	220	PF00454	0.618
MOD_PKA_2	27	33	PF00069	0.567
MOD_PKA_2	58	64	PF00069	0.618
MOD_Plk_1	47	53	PF00069	0.517
MOD_Plk_2-3	63	69	PF00069	0.633
MOD_Plk_4	35	41	PF00069	0.632
MOD_ProDKin_1	127	133	PF00069	0.470
MOD_ProDKin_1	160	166	PF00069	0.525
MOD_ProDKin_1	207	213	PF00069	0.684
MOD_SUMO_rev_2	188	192	PF00179	0.667
TRG_ENDOCYTIC_2	136	139	PF00928	0.577
TRG_NES_CRM1_1	137	149	PF08389	0.512

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4KLZ9	Bodo saltans	28%	94%
A0A3S7X8J2	Leishmania donovani	100%	100%
A4HBE3	Leishmania braziliensis	76%	100%
E9B5L5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q2C1	Leishmania major	91%	100%