Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4IAH9_LEIIN

TriTrypDb:

LINF_340048600

Length:

266

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

Expansion

Sequence features

A4IAH9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAH9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	107	109	PF00675	0.408
CLV_NRD_NRD_1	218	220	PF00675	0.612
CLV_NRD_NRD_1	3	5	PF00675	0.411
CLV_PCSK_KEX2_1	107	109	PF00082	0.408
CLV_PCSK_KEX2_1	211	213	PF00082	0.551
CLV_PCSK_KEX2_1	218	220	PF00082	0.552
CLV_PCSK_KEX2_1	3	5	PF00082	0.411
CLV_PCSK_KEX2_1	49	51	PF00082	0.291
CLV_PCSK_PC1ET2_1	211	213	PF00082	0.558
CLV_PCSK_PC1ET2_1	218	220	PF00082	0.546
CLV_PCSK_PC1ET2_1	49	51	PF00082	0.291
CLV_PCSK_SKI1_1	211	215	PF00082	0.628
CLV_PCSK_SKI1_1	45	49	PF00082	0.378
CLV_PCSK_SKI1_1	53	57	PF00082	0.372
CLV_PCSK_SKI1_1	93	97	PF00082	0.449
DEG_Nend_Nbox_1	1	3	PF02207	0.703
DEG_SCF_FBW7_1	224	231	PF00400	0.442
DOC_CKS1_1	225	230	PF01111	0.401
DOC_CYCLIN_yCln2_LP_2	186	192	PF00134	0.394
DOC_MAPK_gen_1	197	205	PF00069	0.418
DOC_MAPK_gen_1	3	9	PF00069	0.666
DOC_MAPK_gen_1	48	58	PF00069	0.509
DOC_MAPK_MEF2A_6	49	58	PF00069	0.564
DOC_USP7_MATH_1	228	232	PF00917	0.418
DOC_USP7_MATH_1	251	255	PF00917	0.465
DOC_USP7_UBL2_3	44	48	PF12436	0.524
DOC_USP7_UBL2_3	49	53	PF12436	0.517
DOC_WW_Pin1_4	224	229	PF00397	0.461
DOC_WW_Pin1_4	254	259	PF00397	0.386
LIG_14-3-3_CanoR_1	120	126	PF00244	0.642
LIG_14-3-3_CanoR_1	163	169	PF00244	0.399
LIG_BIR_III_2	221	225	PF00653	0.326
LIG_CSL_BTD_1	186	189	PF09270	0.394
LIG_deltaCOP1_diTrp_1	184	190	PF00928	0.477
LIG_FHA_1	113	119	PF00498	0.610
LIG_FHA_1	259	265	PF00498	0.383
LIG_FHA_2	41	47	PF00498	0.555
LIG_LIR_Gen_1	135	143	PF02991	0.313
LIG_LIR_Gen_1	66	75	PF02991	0.506
LIG_LIR_Nem_3	135	139	PF02991	0.325
LIG_LIR_Nem_3	66	72	PF02991	0.532
LIG_PDZ_Class_2	261	266	PF00595	0.359
LIG_SH2_CRK	111	115	PF00017	0.631
LIG_SH2_GRB2like	111	114	PF00017	0.615
LIG_SH2_STAP1	155	159	PF00017	0.355
LIG_SH2_STAP1	168	172	PF00017	0.441
LIG_SH2_STAT5	150	153	PF00017	0.394
LIG_SH2_STAT5	155	158	PF00017	0.314
LIG_SH2_STAT5	226	229	PF00017	0.427
LIG_SH3_3	222	228	PF00018	0.388
LIG_SH3_3	242	248	PF00018	0.374
LIG_SUMO_SIM_anti_2	201	207	PF11976	0.419
LIG_WW_1	223	226	PF00397	0.478
MOD_CK1_1	164	170	PF00069	0.369
MOD_CK1_1	254	260	PF00069	0.487
MOD_CK2_1	164	170	PF00069	0.370
MOD_CMANNOS	187	190	PF00535	0.583
MOD_GlcNHglycan	18	21	PF01048	0.445
MOD_GlcNHglycan	230	233	PF01048	0.647
MOD_GlcNHglycan	253	256	PF01048	0.705
MOD_GlcNHglycan	4	7	PF01048	0.469
MOD_GSK3_1	224	231	PF00069	0.459
MOD_GSK3_1	253	260	PF00069	0.389
MOD_N-GLC_1	112	117	PF02516	0.408
MOD_NEK2_1	114	119	PF00069	0.609
MOD_NEK2_1	2	7	PF00069	0.641
MOD_NEK2_1	206	211	PF00069	0.332
MOD_NEK2_1	78	83	PF00069	0.586
MOD_PKA_2	119	125	PF00069	0.613
MOD_PKA_2	164	170	PF00069	0.356
MOD_PKA_2	2	8	PF00069	0.626
MOD_Plk_4	29	35	PF00069	0.518
MOD_ProDKin_1	224	230	PF00069	0.460
MOD_ProDKin_1	254	260	PF00069	0.385
MOD_SUMO_for_1	95	98	PF00179	0.658
TRG_DiLeu_BaEn_1	74	79	PF01217	0.509
TRG_ENDOCYTIC_2	11	14	PF00928	0.601
TRG_ENDOCYTIC_2	111	114	PF00928	0.589
TRG_ER_diArg_1	106	108	PF00400	0.611
TRG_ER_diArg_1	162	165	PF00400	0.365
TRG_ER_diArg_1	2	4	PF00400	0.615
TRG_NLS_MonoExtN_4	45	52	PF00514	0.552

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILG9	Leptomonas seymouri	73%	100%
A0A0S4KRJ1	Bodo saltans	43%	100%
A0A1X0PA98	Trypanosomatidae	54%	100%
A0A3S7X8J5	Leishmania donovani	100%	100%
A0A422NVC0	Trypanosoma rangeli	54%	100%
A4HBD1	Leishmania braziliensis	84%	100%
C9ZLR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
E9B5K3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q2D3	Leishmania major	93%	100%