Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4IAE3_LEIIN

TriTrypDb:

LINF_340045100

Length:

517

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4IAE3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4IAE3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	424	428	PF00656	0.729
CLV_C14_Caspase3-7	49	53	PF00656	0.608
CLV_NRD_NRD_1	287	289	PF00675	0.622
CLV_NRD_NRD_1	334	336	PF00675	0.671
CLV_NRD_NRD_1	35	37	PF00675	0.662
CLV_NRD_NRD_1	363	365	PF00675	0.737
CLV_NRD_NRD_1	402	404	PF00675	0.721
CLV_NRD_NRD_1	509	511	PF00675	0.458
CLV_PCSK_KEX2_1	149	151	PF00082	0.643
CLV_PCSK_KEX2_1	162	164	PF00082	0.478

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5K2	Leptomonas seymouri	37%	89%
A0A3Q8INS4	Leishmania donovani	98%	100%
A4HB95	Leishmania braziliensis	59%	100%
E9B5G7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4Q2G8	Leishmania major	84%	100%

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